Bernd Clement
Pharmazeutisches Institut
Christian-Albrechts-Universität zu Kiel
Gutenbergstrasse 76
D-24118 Kiel
Germany
Name/email consistency: high
- Reduction of Nomega-hydroxy-L-arginine to L-arginine by pig liver microsomes, mitochondria, and human liver microsomes. Clement, B., Kunze, T., Heberling, S. Biochem. Biophys. Res. Commun. (2006)
- Diacetyldiamidoximeester of pentamidine, a prodrug for treatment of protozoal diseases: synthesis, in vitro and in vivo biotransformation. Clement, B., Bürenheide, A., Rieckert, W., Schwarz, J. ChemMedChem (2006)
- A two-step synthesis of cytostatically active benzo[c]phenanthridine derivatives. Clement, B., Weide, M., Wolschendorf, U., Kock, I. Angew. Chem. Int. Ed. Engl. (2005)
- Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid). Clement, B., Mau, S., Deters, S., Havemeyer, A. Drug Metab. Dispos. (2005)
- Characterization of in vitro biotransformation of new, orally active, direct thrombin inhibitor ximelagatran, an amidoxime and ester prodrug. Clement, B., Lopian, K. Drug Metab. Dispos. (2003)
- Reduction of N-hydroxylated compounds: amidoximes (N-hydroxyamidines) as pro-drugs of amidines. Clement, B. Drug Metab. Rev. (2002)
- Reduction of amphetamine hydroxylamine and other aliphatic hydroxylamines by benzamidoxime reductase and human liver microsomes. Clement, B., Behrens, D., Möller, W., Cashman, J.R. Chem. Res. Toxicol. (2000)