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Bernd Clement

Pharmazeutisches Institut

Christian-Albrechts-Universität zu Kiel

Gutenbergstrasse 76

D-24118 Kiel



Name/email consistency: high



  • Pharmazeutisches Institut, Christian-Albrechts-Universität zu Kiel, Gutenbergstrasse 76, D-24118 Kiel, Germany. 2000 - 2006
  • Institute of Pharmacy, Christian-Albrechts-University of Kiel, Germany. 2005
  • Pharmaceutical Institute, University of Kiel, Germany. 2002


  1. Reduction of Nomega-hydroxy-L-arginine to L-arginine by pig liver microsomes, mitochondria, and human liver microsomes. Clement, B., Kunze, T., Heberling, S. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  2. Diacetyldiamidoximeester of pentamidine, a prodrug for treatment of protozoal diseases: synthesis, in vitro and in vivo biotransformation. Clement, B., Bürenheide, A., Rieckert, W., Schwarz, J. ChemMedChem (2006) [Pubmed]
  3. A two-step synthesis of cytostatically active benzo[c]phenanthridine derivatives. Clement, B., Weide, M., Wolschendorf, U., Kock, I. Angew. Chem. Int. Ed. Engl. (2005) [Pubmed]
  4. Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid). Clement, B., Mau, S., Deters, S., Havemeyer, A. Drug Metab. Dispos. (2005) [Pubmed]
  5. Characterization of in vitro biotransformation of new, orally active, direct thrombin inhibitor ximelagatran, an amidoxime and ester prodrug. Clement, B., Lopian, K. Drug Metab. Dispos. (2003) [Pubmed]
  6. Reduction of N-hydroxylated compounds: amidoximes (N-hydroxyamidines) as pro-drugs of amidines. Clement, B. Drug Metab. Rev. (2002) [Pubmed]
  7. Reduction of amphetamine hydroxylamine and other aliphatic hydroxylamines by benzamidoxime reductase and human liver microsomes. Clement, B., Behrens, D., Möller, W., Cashman, J.R. Chem. Res. Toxicol. (2000) [Pubmed]
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