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Toshimitsu Niwa

Dept. Advanced Medicine for Uremia

Nagoya Univ. Graduate School of Medicine

65 Tsurumai-cho

Showa-ku

Japan

[email]@med.nagoya-u.ac.jp

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Affiliations

Dept. Advanced Medicine for Uremia, Nagoya Univ. Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Japan. 2001 - 2012
Nagoya University Hospital, Department of Clinical Preventive Medicine, Showa-ku, Nagoya 466-8560, Japan. 2007 - 2009
Nagoya University Daiko Medical Center, Japan. 1998 - 2001

References

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress. Muteliefu, G., Shimizu, H., Enomoto, A., Nishijima, F., Takahashi, M., Niwa, T. Am. J. Physiol., Cell Physiol. (2012) [Pubmed]
Indoxyl sulfate induces nephrovascular senescence. Niwa, T., Shimizu, H. J. Ren. Nutr (2012) [Pubmed]
Update of uremic toxin research by mass spectrometry. Niwa, T. Mass. Spectrom. Rev (2011) [Pubmed]
Role of indoxyl sulfate in the progression of chronic kidney disease and cardiovascular disease: experimental and clinical effects of oral sorbent AST-120. Niwa, T. Ther. Apher. Dial (2011) [Pubmed]
NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells. Shimizu, H., Bolati, D., Adijiang, A., Muteliefu, G., Enomoto, A., Nishijima, F., Dateki, M., Niwa, T. Am. J. Physiol., Cell Physiol. (2011) [Pubmed]
Uremic toxicity of indoxyl sulfate. Niwa, T. Nagoya. J. Med. Sci (2010) [Pubmed]
Indoxyl sulfate is a nephro-vascular toxin. Niwa, T. J. Ren. Nutr (2010) [Pubmed]
Recent progress in the analysis of uremic toxins by mass spectrometry. Niwa, T. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2009) [Pubmed]
Biomarker discovery for kidney diseases by mass spectrometry. Niwa, T. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2008) [Pubmed]
Protein glutathionylation and oxidative stress. Niwa, T. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2007) [Pubmed]
Mass spectrometry for the study of protein glycation in disease. Niwa, T. Mass. Spectrom. Rev (2006) [Pubmed]
3-deoxyglucosone and AGEs in uremic complications: inactivation of glutathione peroxidase by 3-deoxyglucosone. Niwa, T., Tsukushi, S. Kidney Int. Suppl. (2001) [Pubmed]
Dialysis-related amyloidosis: pathogenesis focusing on AGE modification. Niwa, T. Semin. Dial (2001) [Pubmed]
3-Deoxyglucosone: metabolism, analysis, biological activity, and clinical implication. Niwa, T. J. Chromatogr. B Biomed. Sci. Appl. (1999) [Pubmed]
RNA metabolism in uremic patients: accumulation of modified ribonucleosides in uremic serum. Technical note. Niwa, T., Takeda, N., Yoshizumi, H. Kidney Int. (1998) [Pubmed]