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Akira Tokumura

Department of Pharmaceutical Health Chemistry

Institute of Health Biosciences

Shomachi

Tokushima 770-8505

Japan

[email]@ph.tokushima-u.ac.jp

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Pharmaceutical Health Chemistry, Institute of Health Biosciences, Shomachi, Tokushima 770-8505, Japan. 2009
  • Laboratory of Health Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokushima, Shomachi, Japan. 2002 - 2007
  • Faculty of Pharmaceutical Sciences, University of Tokushima, Japan. 1997 - 2004

References

  1. Altered activity of lysophospholipase D, which produces bioactive lysophosphatidic acid and choline, in serum from women with pathological pregnancy. Tokumura, A., Kume, T., Taira, S., Yasuda, K., Kanzaki, H. Mol. Hum. Reprod. (2009) [Pubmed]
  2. Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity. Tokumura, A., Kume, T., Fukuzawa, K., Tahara, M., Tasaka, K., Aoki, J., Arai, H., Yasuda, K., Kanzaki, H. Life Sci. (2007) [Pubmed]
  3. Metabolic pathways and physiological and pathological significances of lysolipid phosphate mediators. Tokumura, A. J. Cell. Biochem. (2004) [Pubmed]
  4. Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits. Tokumura, A., Kanaya, Y., Kitahara, M., Miyake, M., Yoshioka, Y., Fukuzawa, K. J. Lipid Res. (2002) [Pubmed]
  5. Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids. Tokumura, A., Sinomiya, J., Kishimoto, S., Tanaka, T., Kogure, K., Sugiura, T., Satouchi, K., Waku, K., Fukuzawa, K. Biochem. J. (2002) [Pubmed]
  6. Physiological and pathophysiological roles of lysophosphatidic acids produced by secretory lysophospholipase D in body fluids. Tokumura, A. Biochim. Biophys. Acta (2002) [Pubmed]
  7. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase. Tokumura, A., Majima, E., Kariya, Y., Tominaga, K., Kogure, K., Yasuda, K., Fukuzawa, K. J. Biol. Chem. (2002) [Pubmed]
  8. Increased production of bioactive lysophosphatidic acid by serum lysophospholipase D in human pregnancy. Tokumura, A., Kanaya, Y., Miyake, M., Yamano, S., Irahara, M., Fukuzawa, K. Biol. Reprod. (2002) [Pubmed]
  9. Lysophosphatidic acids produced by lysophospholipase D in mammalian serum and body fluid. Tokumura, A., Yamano, S., Aono, T., Fukuzawa, K. Ann. N. Y. Acad. Sci. (2000) [Pubmed]
  10. Platelet-activating factor (PAF)-like oxidized phospholipids: relevance to atherosclerosis. Tokumura, A., Sumida, T., Toujima, M., Kogure, K., Fukuzawa, K. Biofactors (2000) [Pubmed]
  11. Substrate specificity of lysophospholipase D which produces bioactive lysophosphatidic acids in rat plasma. Tokumura, A., Nishioka, Y., Yoshimoto, O., Shinomiya, J., Fukuzawa, K. Biochim. Biophys. Acta (1999) [Pubmed]
  12. Production of lysophosphatidic acid by lysophospholipase D in incubated plasma of spontaneously hypertensive rats and Wistar Kyoto rats. Tokumura, A., Fujimoto, H., Yoshimoto, O., Nishioka, Y., Miyake, M., Fukuzawa, K. Life Sci. (1999) [Pubmed]
  13. Positive and negative controls by protein kinases of sodium-dependent Ca2+ efflux from cultured bovine adrenal chromaffin cells stimulated by lysophosphatidic acid. Tokumura, A., Okuno, M., Fukuzawa, K., Houchi, H., Tsuchiya, K., Oka, M. Biochim. Biophys. Acta (1998) [Pubmed]
  14. Metal-ion stimulation and inhibition of lysophospholipase D which generates bioactive lysophosphatidic acid in rat plasma. Tokumura, A., Miyake, M., Yoshimoto, O., Shimizu, M., Fukuzawa, K. Lipids (1998) [Pubmed]
  15. Exogenously added alkylmethylglycerophosphocholine and alkylmethylcarbamylglycerophosphocholine accumulate in plasma membranes more than in intracellular membranes of rabbit platelets. Tokumura, A., Tsutsumi, T., Nishioka, Y., Tsukatani, H. Chem. Phys. Lipids (1997) [Pubmed]
 
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