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Wei Tang

Department of Drug Metabolism and Pharmacokinetics

Merck Research Laboratories

Rahway

NJ 07065

USA

[email]@merck.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Drug Metabolism and Pharmacokinetics, Merck Research Laboratories, Rahway, NJ 07065, USA. 1999 - 2010
  • Merck Research Laboratories, Department of Drug Metabolism, Rahway, NJ 07065-0900, USA. 2007
  • Department of Drug Metabolism, Merck & Co., PO Box 2000, RY800-B211, USA. 2005

References

  1. Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective. Tang, W., Lu, A.Y. Drug Metab. Rev. (2010) [Pubmed]
  2. Drug metabolism and pharmacokinetics in support of drug design. Tang, W., Lu, A.Y. Curr. Pharm. Des. (2009) [Pubmed]
  3. Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: a case study with melanocortin-4 receptor agonists. Tang, W., Stearns, R.A., Wang, R.W., Miller, R.R., Chen, Q., Ngui, J., Bakshi, R.K., Nargund, R.P., Dean, D.C., Baillie, T.A. Xenobiotica (2008) [Pubmed]
  4. Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats. Tang, W., Stearns, R.A., Chen, Q., Bleasby, K., Teffera, Y., Colletti, A., Hafey, M., Evers, R., Dean, D.C., Magriotis, P.A., Lanza, T.J., Lin, L.S., Hagmann, W.K., Baillie, T.A. Xenobiotica (2008) [Pubmed]
  5. Drug metabolite profiling and elucidation of drug-induced hepatotoxicity. Tang, W. Expert. Opin. Drug. Metab. Toxicol (2007) [Pubmed]
  6. Utility of recombinant cytochrome p450 enzymes: a drug metabolism perspective. Tang, W., Wang, R.W., Lu, A.Y. Curr. Drug Metab. (2005) [Pubmed]
  7. The metabolism of diclofenac--enzymology and toxicology perspectives. Tang, W. Curr. Drug Metab. (2003) [Pubmed]
  8. Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate. Tang, W., Stearns, R.A., Miller, R.R., Ngui, J.S., Mathvink, R.J., Weber, A.E., Kwei, G.Y., Strauss, J.R., Keohane, C.A., Doss, G.A., Chiu, S.H., Baillie, T.A. Drug Metab. Dispos. (2002) [Pubmed]
  9. Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions. Tang, W., Stearns, R.A. Curr. Drug Metab. (2001) [Pubmed]
  10. Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites. Tang, W., Stearns, R.A., Bandiera, S.M., Zhang, Y., Raab, C., Braun, M.P., Dean, D.C., Pang, J., Leung, K.H., Doss, G.A., Strauss, J.R., Kwei, G.Y., Rushmore, T.H., Chiu, S.H., Baillie, T.A. Drug Metab. Dispos. (1999) [Pubmed]
  11. Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism. Tang, W., Stearns, R.A., Kwei, G.Y., Iliff, S.A., Miller, R.R., Egan, M.A., Yu, N.X., Dean, D.C., Kumar, S., Shou, M., Lin, J.H., Baillie, T.A. J. Pharmacol. Exp. Ther. (1999) [Pubmed]
 
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