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Margot W. Beukers

Division of Medicinal Chemistry

Leiden/Amsterdam Center for Drug Research

Einsteinweg 55

2300 RA Leiden

Netherlands

[email]@*.leidenuniv.nl

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Einsteinweg 55, 2300 RA Leiden, Netherlands. 1999 - 2006
  • Division of Medicinal Chemistry, LACDR, Gorlaeus Laboratories, Leiden, Netherlands. 2004

References

  1. Structure-affinity relationships of adenosine A2B receptor ligands. Beukers, M.W., Meurs, I., Ijzerman, A.P. Med. Res. Rev (2006) [Pubmed]
  2. Techniques: how to boost GPCR mutagenesis studies using yeast. Beukers, M.W., Ijzerman, A.P. Trends Pharmacol. Sci. (2005) [Pubmed]
  3. Random mutagenesis of the human adenosine A2B receptor followed by growth selection in yeast. Identification of constitutively active and gain of function mutations. Beukers, M.W., van Oppenraaij, J., van der Hoorn, P.P., Blad, C.C., den Dulk, H., Brouwer, J., IJzerman, A.P. Mol. Pharmacol. (2004) [Pubmed]
  4. New, non-adenosine, high-potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine. Beukers, M.W., Chang, L.C., von Frijtag Drabbe Künzel, J.K., Mulder-Krieger, T., Spanjersberg, R.F., Brussee, J., IJzerman, A.P. J. Med. Chem. (2004) [Pubmed]
  5. N6-cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a very selective agonist with high affinity for the human adenosine A1 receptor. Beukers, M.W., Wanner, M.J., Von Frijtag Drabbe Künzel, J.K., Klaasse, E.C., IJzerman, A.P., Koomen, G.J. J. Med. Chem. (2003) [Pubmed]
  6. TinyGRAP database: a bioinformatics tool to mine G-protein-coupled receptor mutant data. Beukers, M.W., Kristiansen, I., IJzerman, A.P., Edvardsen, I. Trends Pharmacol. Sci. (1999) [Pubmed]
 
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