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Yukihito Higashi

Department of Cardiovascular Regeneration and Medicine

Research Institute for Radiation Biology and Medicine

Hiroshima University

1-2-3 Kasumi

Japan

[email]@hiroshima-u.ac.jp

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Japan. 2012
  • Department of Cardiovascular Physiology and Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. 2002 - 2010
  • Departments of Cardiovascular Physiology, Hiroshima University, Hiroshima, Japan. 2010
  • Hiroshima University, Graduate School of Biomedical Sciences, Department of Cardiovascular Physiology and Medicine, 1-2-3 Kasumi, Japan. 2009
  • First Department of Internal Medicine, Hiroshima University School of Medicine, Japan. 2001 - 2006

References

  1. Hyperbilirubinemia, augmentation of endothelial function, and decrease in oxidative stress in gilbert syndrome. Maruhashi, T., Soga, J., Fujimura, N., Idei, N., Mikami, S., Iwamoto, Y., Kajikawa, M., Matsumoto, T., Kihara, Y., Chayama, K., Noma, K., Nakashima, A., Tomiyama, H., Takase, B., Yamashina, A., Higashi, Y. Circulation (2012) [Pubmed]
  2. Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells. Higashi, Y., Matsuoka, H., Umei, H., Sugano, R., Fujii, Y., Soga, J., Kihara, Y., Chayama, K., Imaizumi, T. Am. J. Physiol. Endocrinol. Metab. (2010) [Pubmed]
  3. Sarpogrelate hydrochloride, a selective 5-hydroxytryptamine(2A) antagonist, augments autologous bone marrow mononuclear cell implantation-induced improvement in endothelium-dependent vasodilation in patients with critical limb ischemia. Higashi, Y., Miyazaki, M., Goto, C., Sanada, H., Sueda, T., Chayama, K. J. Cardiovasc. Pharmacol. (2010) [Pubmed]
  4. Endothelial function and oxidative stress in cardiovascular diseases. Higashi, Y., Noma, K., Yoshizumi, M., Kihara, Y. Circ. J. (2009) [Pubmed]
  5. Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease. Higashi, Y., Goto, C., Hidaka, T., Soga, J., Nakamura, S., Fujii, Y., Hata, T., Idei, N., Fujimura, N., Chayama, K., Kihara, Y., Taguchi, A. Atherosclerosis (2009) [Pubmed]
  6. Edaravone for the treatment of acute cerebral infarction: role of endothelium-derived nitric oxide and oxidative stress. Higashi, Y. Expert. Opin. Pharmacother (2009) [Pubmed]
  7. Cigarette smoking abolishes ischemic preconditioning-induced augmentation of endothelium-dependent vasodilation. Nakamura, S., Kimura, M., Goto, C., Noma, K., Yoshizumi, M., Chayama, K., Kihara, Y., Higashi, Y. Hypertension (2009) [Pubmed]
  8. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients. Higashi, Y., Goto, C., Jitsuiki, D., Umemura, T., Nishioka, K., Hidaka, T., Takemoto, H., Nakamura, S., Soga, J., Chayama, K., Yoshizumi, M., Taguchi, A. Hypertension (2008) [Pubmed]
  9. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases. Higashi, Y., Jitsuiki, D., Chayama, K., Yoshizumi, M. Recent. Pat. Cardiovasc. Drug. Discov (2006) [Pubmed]
  10. Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production. Higashi, Y., Sasaki, S., Nakagawa, K., Kimura, M., Noma, K., Hara, K., Jitsuiki, D., Goto, C., Oshima, T., Chayama, K., Yoshizumi, M. Atherosclerosis (2006) [Pubmed]
  11. Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy. Higashi, Y., Nishioka, K., Umemura, T., Chayama, K., Yoshizumi, M. Curr. Pharm. Biotechnol (2006) [Pubmed]
  12. Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress. Higashi, Y., Chayama, K., Yoshizumi, M. Curr. Med. Chem. Cardiovasc. Hematol. Agents (2005) [Pubmed]
  13. Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia. Higashi, Y., Kimura, M., Hara, K., Noma, K., Jitsuiki, D., Nakagawa, K., Oshima, T., Chayama, K., Sueda, T., Goto, C., Matsubara, H., Murohara, T., Yoshizumi, M. Circulation (2004) [Pubmed]
  14. Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress. Higashi, Y., Sasaki, S., Nakagawa, K., Kimura, M., Noma, K., Sasaki, S., Hara, K., Matsuura, H., Goto, C., Oshima, T., Chayama, K., Yoshizumi, M. J. Am. Coll. Cardiol. (2003) [Pubmed]
  15. New methods to evaluate endothelial function: method for assessing endothelial function in humans using a strain-gauge plethysmography: nitric oxide-dependent and -independent vasodilation. Higashi, Y., Yoshizumi, M. J. Pharmacol. Sci. (2003) [Pubmed]
  16. Renal endothelial dysfunction and hypertension. Higashi, Y., Chayama, K. J. Diabetes Complicat. (2002) [Pubmed]
  17. Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma. Higashi, Y., Sasaki, S., Nakagawa, K., Kimura, M., Sasaki, S., Noma, K., Matsuura, H., Hara, K., Goto, C., Oshima, T., Chayama, K. Hypertension (2002) [Pubmed]
  18. Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition. Higashi, Y., Sasaki, S., Nakagawa, K., Kimura, M., Sasaki, S., Noma, K., Hara, K., Matsuura, H., Goto, C., Oshima, T., Chayama, K. J. Cardiovasc. Pharmacol. (2002) [Pubmed]
  19. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals. Higashi, Y., Sasaki, S., Nakagawa, K., Fukuda, Y., Matsuura, H., Oshima, T., Chayama, K. Am. J. Hypertens. (2002) [Pubmed]
  20. Endothelial function and oxidative stress in renovascular hypertension. Higashi, Y., Sasaki, S., Nakagawa, K., Matsuura, H., Oshima, T., Chayama, K. N. Engl. J. Med. (2002) [Pubmed]
  21. Circadian variation of blood pressure and endothelial function in patients with essential hypertension:a comparison of dippers and non-dippers. Higashi, Y., Nakagawa, K., Kimura, M., Noma, K., Hara, K., Sasaki, S., Goto, C., Oshima, T., Chayama, K., Yoshizumi, M. J. Am. Coll. Cardiol. (2002) [Pubmed]
  22. Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension. Higashi, Y., Sasaki, S., Nakagawa, K., Matsuura, H., Chayama, K., Oshima, T. Am. J. Hypertens. (2001) [Pubmed]
  23. Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension. Higashi, Y., Sasaki, S., Nakagawa, K., Kimura, M., Noma, K., Sasaki, S., Hara, K., Matsuura, H., Chayama, K., Oshima, T. Hypertens. Res. (2001) [Pubmed]
 
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