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Yunsheng Hsieh

Department of Drug Metabolism and Pharmacokinetics and Department of Medicinal Chemistry; Schering-Plough Research Institute

Kenilworth

NJ 07033

USA

[email]@spcorp.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Drug Metabolism and Pharmacokinetics and Department of Medicinal Chemistry; Schering-Plough Research Institute, Kenilworth, NJ 07033, USA. 2002 - 2009
  • Schering-Plough Research Institute, 2015 Galloping Hill Road, K-15-3700, Kenilworth, USA. 2009
  • Schering-Plough Research Institute, Department of Drug Metabolism and Pharmacokinetics, 2015 Galloping Hill Road, K-15-3700, USA. 2008

References

  1. The role of exploratory drug metabolism and pharmacokinetics in new drug research: case study-selection of a thrombin receptor antagonist for development. Hsieh, Y., Cheng, K.C., Wang, Y., Chackalamannil, S., Xia, Y., Korfmacher, W.A., White, R.E. Curr. Pharm. Des. (2009) [Pubmed]
  2. Ultra-performance hydrophilic interaction liquid chromatography/tandem mass spectrometry for the determination of everolimus in mouse plasma. Hsieh, Y., Galviz, G., Long, B.J. Rapid Commun. Mass Spectrom. (2009) [Pubmed]
  3. Ultra-performance hydrophilic interaction LC-MS/MS for the determination of metformin in mouse plasma. Hsieh, Y., Galviz, G., Hwa, J.J. Bioanalysis (2009) [Pubmed]
  4. Hydrophilic interaction liquid chromatography/tandem mass spectrometry for the simultaneous determination of dasatinib, imatinib and nilotinib in mouse plasma. Hsieh, Y., Galviz, G., Zhou, Q., Duncan, C. Rapid Commun. Mass Spectrom. (2009) [Pubmed]
  5. The role of hyphenated chromatography-mass spectrometry techniques in exploratory drug metabolism and pharmacokinetics. Hsieh, Y., Korfmacher, W. Curr. Pharm. Des. (2009) [Pubmed]
  6. HPLC-MS/MS in drug metabolism and pharmacokinetic screening. Hsieh, Y. Expert. Opin. Drug. Metab. Toxicol (2008) [Pubmed]
  7. Potential of HILIC-MS in quantitative bioanalysis of drugs and drug metabolites. Hsieh, Y. J. Sep. Sci (2008) [Pubmed]
  8. Porous graphitic carbon chromatography/tandem mass spectrometric determination of cytarabine in mouse plasma. Hsieh, Y., Duncan, C.J., Brisson, J.M. Rapid Commun. Mass Spectrom. (2007) [Pubmed]
  9. Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry. Hsieh, Y., Chen, J., Korfmacher, W.A. J. Pharmacol. Toxicol. Methods (2007) [Pubmed]
  10. Comparison of fast liquid chromatography/tandem mass spectrometric methods for simultaneous determination of cladribine and clofarabine in mouse plasma. Hsieh, Y., Duncan, C.J., Lee, S., Liu, M. J. Pharm. Biomed. Anal (2007) [Pubmed]
  11. A mixed-mode liquid chromatography-tandem mass spectrometric method for the determination of cytarabine in mouse plasma. Hsieh, Y., Duncan, C.J., Liu, M. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2007) [Pubmed]
  12. Supercritical fluid chromatography and high-performance liquid chromatography/tandem mass spectrometric methods for the determination of cytarabine in mouse plasma. Hsieh, Y., Li, F., Duncan, C.J. Anal. Chem. (2007) [Pubmed]
  13. An ion-pairing liquid chromatography/tandem mass spectrometric method for the determination of cytarabine in mouse plasma. Hsieh, Y., Duncan, C.J. Rapid Commun. Mass Spectrom. (2007) [Pubmed]
  14. Increasing speed and throughput when using HPLC-MS/MS systems for drug metabolism and pharmacokinetic screening. Hsieh, Y., Korfmacher, W.A. Curr. Drug Metab. (2006) [Pubmed]
  15. Supercritical fluid chromatography/tandem mass spectrometric method for analysis of pharmaceutical compounds in metabolic stability samples. Hsieh, Y., Favreau, L., Schwerdt, J., Cheng, K.C. J. Pharm. Biomed. Anal (2006) [Pubmed]
  16. Fast mass spectrometry-based methodologies for pharmaceutical analyses. Hsieh, Y., Fukuda, E., Wingate, J., Korfmacher, W.A. Comb. Chem. High Throughput Screen. (2006) [Pubmed]
  17. Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue. Hsieh, Y., Casale, R., Fukuda, E., Chen, J., Knemeyer, I., Wingate, J., Morrison, R., Korfmacher, W. Rapid Commun. Mass Spectrom. (2006) [Pubmed]
  18. Simultaneous determination of nicotinic acid and its metabolites using hydrophilic interaction chromatography with tandem mass spectrometry. Hsieh, Y., Chen, J. Rapid Commun. Mass Spectrom. (2005) [Pubmed]
  19. Chiral supercritical fluid chromatography/tandem mass spectrometry for the simultaneous determination of pindolol and propranolol in metabolic stability samples. Hsieh, Y., Favreau, L., Cheng, K.C., Chen, J. Rapid Commun. Mass Spectrom. (2005) [Pubmed]
  20. Direct plasma analysis of drug compounds using monolithic column liquid chromatography and tandem mass spectrometry. Hsieh, Y., Wang, G., Wang, Y., Chackalamannil, S., Korfmacher, W.A. Anal. Chem. (2003) [Pubmed]
  21. Zirconia-based column high-performance liquid chromatography/atmospheric pressure photoionization tandem mass spectrometric analyses of drug molecules in rat plasma. Hsieh, Y., Merkle, K., Wang, G. Rapid Commun. Mass Spectrom. (2003) [Pubmed]
  22. High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma. Hsieh, Y., Merkle, K., Wang, G., Brisson, J.M., Korfmacher, W.A. Anal. Chem. (2003) [Pubmed]
  23. Simultaneous fast HPLC-MS/MS analysis of drug candidates and hydroxyl metabolites in plasma. Hsieh, Y., Brisson, J.M., Wang, G., Ng, K., Korfmacher, W.A. J. Pharm. Biomed. Anal (2003) [Pubmed]
  24. Direct simultaneous determination of drug discovery compounds in monkey plasma using mixed-function column liquid chromatography/tandem mass spectrometry. Hsieh, Y., Brisson, J.M., Ng, K., Korfmacher, W.A. J. Pharm. Biomed. Anal (2002) [Pubmed]
  25. Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography-tandem mass spectrometry. Hsieh, Y., Bryant, M.S., Brisson, J.M., Ng, K., Korfmacher, W.A. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2002) [Pubmed]
  26. Simultaneous determination of a drug candidate and its metabolite in rat plasma samples using ultrafast monolithic column high-performance liquid chromatography/tandem mass spectrometry. Hsieh, Y., Wang, G., Wang, Y., Chackalamannil, S., Brisson, J.M., Ng, K., Korfmacher, W.A. Rapid Commun. Mass Spectrom. (2002) [Pubmed]
 
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