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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Bo Wen

Hoffmann-La Roche

Inc., 340 Kingsland Street

123/1341

[email]@roche.com

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Affiliations

Hoffmann-La Roche, Inc., 340 Kingsland Street, 123/1341. 2011
Department of Drug Metabolism and Pharmacokinetics, Roche Palo Alto, CA 94304, USA. 2008 - 2009
Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, New Jersey 08543, USA. 2008

References

Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH Conjugates. Wen, B., Moore, D.J. Drug Metab. Dispos. (2011) [Pubmed]
Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s. Wen, B., Zhou, M. Chem. Biol. Interact. (2009) [Pubmed]
Analytical strategies for the screening and evaluation of chemically reactive drug metabolites. Wen, B., Fitch, W.L. Expert. Opin. Drug. Metab. Toxicol (2009) [Pubmed]
Metabolic activation of nevirapine in human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4. Wen, B., Chen, Y., Fitch, W.L. Drug Metab. Dispos. (2009) [Pubmed]
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry. Wen, B., Fitch, W.L. J. Mass. Spectrom (2009) [Pubmed]
High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry. Wen, B., Ma, L., Nelson, S.D., Zhu, M. Anal. Chem. (2008) [Pubmed]
Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s. Wen, B., Ma, L., Zhu, M. Chem. Biol. Interact. (2008) [Pubmed]
Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine. Wen, B., Ma, L., Rodrigues, A.D., Zhu, M. Drug Metab. Dispos. (2008) [Pubmed]