Clive Bate
Department of Pathology and Infectious Diseases
Royal Veterinary College
Hawkshead Lane
North Mymms
United Kingdom
Name/email consistency: high
- Monoacylated cellular prion protein modifies cell membranes, inhibits cell signaling, and reduces prion formation. Bate, C., Williams, A. J. Biol. Chem. (2011)
- The glycosylphosphatidylinositol anchor is a major determinant of prion binding and replication. Bate, C., Tayebi, M., Williams, A. Biochem. J. (2010)
- Polyunsaturated fatty acids protect against prion-mediated synapse damage in vitro. Bate, C., Tayebi, M., Salmona, M., Diomede, L., Williams, A. Neurotox. Res (2010)
- Phospholipase A2 inhibitors protect against prion and Abeta mediated synapse degeneration. Bate, C., Tayebi, M., Williams, A. Mol. Neurodegener (2010)
- Amyloid-β(1-40) inhibits amyloid-β(1-42) induced activation of cytoplasmic phospholipase A2 and synapse degeneration. Bate, C., Williams, A. J. Alzheimers Dis. (2010)
- A glycosylphosphatidylinositol analogue reduced prion-derived peptide mediated activation of cytoplasmic phospholipase A2, synapse degeneration and neuronal death. Bate, C., Tayebi, M., Williams, A. Neuropharmacology (2010)
- Glimepiride reduces the expression of PrPc, prevents PrPSc formation and protects against prion mediated neurotoxicity in cell lines. Bate, C., Tayebi, M., Diomede, L., Salmona, M., Williams, A. PLoS. ONE (2009)
- Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activation. Bate, C., Tayebi, M., Williams, A. BMC Biol. (2008)
- Ginkgolides protect against amyloid-beta1-42-mediated synapse damage in vitro. Bate, C., Tayebi, M., Williams, A. Mol. Neurodegener (2008)
- Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells. Bate, C., Tayebi, M., Diomede, L., Salmona, M., Williams, A. BMC Biol. (2008)
- Cholesterol esterification reduces the neurotoxicity of prions. Bate, C., Tayebi, M., Williams, A. Neuropharmacology (2008)
- Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A2 by Abeta(1-42). Bate, C., Williams, A. Neuropharmacology (2007)
- Cholesterol synthesis inhibitors protect against platelet-activating factor-induced neuronal damage. Bate, C., Rumbold, L., Williams, A. J. Neuroinflammation (2007)
- Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Bate, C., Kempster, S., Williams, A. Neuropharmacology (2006)
- Interferon-gamma increases neuronal death in response to amyloid-beta1-42. Bate, C., Kempster, S., Last, V., Williams, A. J. Neuroinflammation (2006)
- Platelet-activating factor antagonists protect amyloid-beta damaged neurons from microglia-mediated death. Bate, C., Kempster, S., Williams, A. Neuropharmacology (2006)
- Microglial cells kill prion-damaged neurons in vitro by a CD14-dependent process. Bate, C., Boshuizen, R., Williams, A. J. Neuroimmunol. (2005)