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Claudiu T. Supuran

Università degli Studi di Firenze

Dipartimento di Scienze farmaceutiche

Via Ugo Schiff 6

50019 Sesto Fiorentino (Florence)



Name/email consistency: high



  • Università degli Studi di Firenze, Dipartimento di Scienze farmaceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino (Florence), Italy. 2012
  • Università degli Studi di Firenze, Laboratorio di Chimica Bioinorganica, Rm. 188, Via della Lastruccia 3. 2002 - 2012


  1. Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092). Supuran, C.T. Expert. Opin. Ther. Pat (2012) [Pubmed]
  2. Sulfonamides: a patent review (2008 - 2012). Carta, F., Scozzafava, A., Supuran, C.T. Expert. Opin. Ther. Pat (2012) [Pubmed]
  3. Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations. Carta, F., Aggarwal, M., Maresca, A., Scozzafava, A., McKenna, R., Supuran, C.T. Chem. Commun. (Camb.) (2012) [Pubmed]
  4. Inhibition of bacterial carbonic anhydrases and zinc proteases: from orphan targets to innovative new antibiotic drugs. Supuran, C.T. Curr. Med. Chem. (2012) [Pubmed]
  5. Inhibition of V-ATPase and Carbonic Anhydrases as Interference Strategy with Tumor Acidification Processes. Perez-Sayans, M., Garcia-Garcia, A., Scozzafava, A., Supuran, C.T. Curr. Pharm. Des. (2012) [Pubmed]
  6. Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanisms. Supuran, C.T. Mol. Divers. (2011) [Pubmed]
  7. Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets. Supuran, C.T. Curr. Pharm. Des. (2010) [Pubmed]
  8. Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII. Supuran, C.T., Di Fiore, A., Alterio, V., Monti, S.M., De Simone, G. Curr. Pharm. Des. (2010) [Pubmed]
  9. Carbonic anhydrase inhibitors. Supuran, C.T. Bioorg. Med. Chem. Lett. (2010) [Pubmed]
  10. Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides. Supuran, C.T. Curr. Pharm. Des. (2008) [Pubmed]
  11. Carbonic anhydrases--an overview. Supuran, C.T. Curr. Pharm. Des. (2008) [Pubmed]
  12. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Supuran, C.T. Nat. Rev. Drug. Discov (2008) [Pubmed]
  13. Carbonic anhydrase inhibitors: the X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitors. Temperini, C., Winum, J.Y., Montero, J.L., Scozzafava, A., Supuran, C.T. Bioorg. Med. Chem. Lett. (2007) [Pubmed]
  14. Carbonic anhydrases as targets for medicinal chemistry. Supuran, C.T., Scozzafava, A. Bioorg. Med. Chem. (2007) [Pubmed]
  15. Carbonic anhydrases as drug targets--an overview. Supuran, C.T. Curr. Top. Med. Chem (2007) [Pubmed]
  16. Phosphodiesterase 5 inhibitors--drug design and differentiation based on selectivity, pharmacokinetic and efficacy profiles. Supuran, C.T., Mastrolorenzo, A., Barbaro, G., Scozzafava, A. Curr. Pharm. Des. (2006) [Pubmed]
  17. Antiviral sulfonamide derivatives. Supuran, C.T., Innocenti, A., Mastrolorenzo, A., Scozzafava, A. Mini. Rev. Med. Chem (2004) [Pubmed]
  18. COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents. Supuran, C.T., Casini, A., Mastrolorenzo, A., Scozzafava, A. Mini. Rev. Med. Chem (2004) [Pubmed]
  19. Designing of Novel Carbonic Anhydrase Inhibitors and Activators. Supuran, C.T., Vullo, D., Manole, G., Casini, A., Scozzafava, A. Curr. Med. Chem. Cardiovasc. Hematol. Agents (2004) [Pubmed]
  20. Designing of novel carbonic anhydrase inhibitors and activators. Supuran, C.T., Vullo, D., Manole, G., Casini, A., Scozzafava, A. Curr. Med. Chem. Cardiovasc. Hematol. Agents (2004) [Pubmed]
  21. Quantum theoretic QSAR of benzene derivatives: some enzyme inhibitors. Supuran, C.T., Clare, B.W. J. Enzyme. Inhib. Med. Chem (2004) [Pubmed]
  22. Benzolamide is not a membrane-impermeant carbonic anhydrase inhibitor. Supuran, C.T., Scozzafava, A. J. Enzyme. Inhib. Med. Chem (2004) [Pubmed]
  23. Carbonic anhydrase inhibitors. Supuran, C.T., Scozzafava, A., Casini, A. Med. Res. Rev (2003) [Pubmed]
  24. Indisulam: an anticancer sulfonamide in clinical development. Supuran, C.T. Expert. Opin. Investig. Drugs (2003) [Pubmed]
  25. Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents. Supuran, C.T., Casini, A., Scozzafava, A. Med. Res. Rev (2003) [Pubmed]
  26. Bacterial protease inhibitors. Supuran, C.T., Scozzafava, A., Clare, B.W. Med. Res. Rev (2002) [Pubmed]
  27. Indisulam. Eisai. Supuran, C.T. IDrugs (2002) [Pubmed]
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