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David Kirkland

Covance Laboratories Ltd.

Otley Road

Harrogate HG3 1PY United Kingdom

[email]@covance.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Covance Laboratories Ltd., Otley Road, Harrogate HG3 1PY United Kingdom. 2005 - 2008
  • Covance Laboratories, Harrogate, North Yorkshire, UK. 1998 - 2007

References

  1. Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: a follow-up to an ECVAM workshop. Kirkland, D., Kasper, P., Müller, L., Corvi, R., Speit, G. Mutat. Res. (2008) [Pubmed]
  2. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate follow-up testing in vivo. Kirkland, D., Speit, G. Mutat. Res. (2008) [Pubmed]
  3. In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results. Kirkland, D.J., Aardema, M., Banduhn, N., Carmichael, P., Fautz, R., Meunier, J.R., Pfuhler, S. Mutagenesis (2007) [Pubmed]
  4. Summary of major conclusions from the 4th IWGT, San Francisco, 9-10 September, 2005. Kirkland, D.J., Hayashi, M., Jacobson-Kram, D., Kasper, P., MacGregor, J.T., Müller, L., Uno, Y. Mutat. Res. (2007) [Pubmed]
  5. Failure of antimony trioxide to induce micronuclei or chromosomal aberrations in rat bone-marrow after sub-chronic oral dosing. Kirkland, D., Whitwell, J., Deyo, J., Serex, T. Mutat. Res. (2007) [Pubmed]
  6. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop. Kirkland, D., Pfuhler, S., Tweats, D., Aardema, M., Corvi, R., Darroudi, F., Elhajouji, A., Glatt, H., Hastwell, P., Hayashi, M., Kasper, P., Kirchner, S., Lynch, A., Marzin, D., Maurici, D., Meunier, J.R., Müller, L., Nohynek, G., Parry, J., Parry, E., Thybaud, V., Tice, R., van Benthem, J., Vanparys, P., White, P. Mutat. Res. (2007) [Pubmed]
  7. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles. Kirkland, D., Aardema, M., Müller, L., Makoto, H. Mutat. Res. (2006) [Pubmed]
  8. Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes. Kirkland, D., Beevers, C. Mutat. Res. (2006) [Pubmed]
  9. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity. Kirkland, D., Aardema, M., Henderson, L., Müller, L. Mutat. Res. (2005) [Pubmed]
  10. Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes. Kirkland, D.J., Henderson, L., Marzin, D., Müller, L., Parry, J.M., Speit, G., Tweats, D.J., Williams, G.M. Mutat. Res. (2005) [Pubmed]
  11. An assessment of the genotoxicity of 2-hydroxy-1,4-naphthoquinone, the natural dye ingredient of Henna. Kirkland, D., Marzin, D. Mutat. Res. (2003) [Pubmed]
  12. Summary of major conclusions. Kirkland, D.J., Hayashi, M., MacGregor, J.T., Müller, L., Schechtman, L.M., Sofuni, T. Mutat. Res. (2003) [Pubmed]
  13. Interpretation of the biological relevance of genotoxicity test results: the importance of thresholds. Kirkland, D.J., Müller, L. Mutat. Res. (2000) [Pubmed]
  14. Summary of major conclusions from the International Workshop on Genotoxicity Test Procedures. Kirkland, D.J., Hayashi, M., MacGregor, J.T., Müller, L., Schechtman, L., Sofuni, T. Environ. Mol. Mutagen. (2000) [Pubmed]
  15. Recommendations for spacing of test chemical concentrations in the mouse lymphoma tk mutation assay (MLA). Kirkland, D.J., Clements, J. Mutat. Res. (1998) [Pubmed]
 
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