Dirk R. J. Kuypers
Department of Nephrology and Renal Transplantation
University Hospitals Leuven
Herestraat 49
B-3000 Leuven
Belgium
Name/email consistency: high
- Management of polyomavirus-associated nephropathy in renal transplant recipients. Kuypers, D.R. Nat. Rev. Nephrol (2012)
- Emerging immunosuppressive drugs in kidney transplantation. Metalidis, C., Kuypers, D.R. Curr. Clin. Pharmacol (2011)
- Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation. Kuypers, D.R., Le Meur, Y., Cantarovich, M., Tredger, M.J., Tett, S.E., Cattaneo, D., Tönshoff, B., Holt, D.W., Chapman, J., Gelder, T. Clin. J. Am. Soc. Nephrol (2010)
- Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients. Kuypers, D.R., Naesens, M., de Jonge, H., Lerut, E., Verbeke, K., Vanrenterghem, Y. Ther. Drug. Monit (2010)
- A prospective, open-label, observational clinical cohort study of the association between delayed renal allograft function, tacrolimus exposure, and CYP3A5 genotype in adult recipients. Kuypers, D.R., de Jonge, H., Naesens, M., Vanrenterghem, Y. Clin. Ther (2010)
- Research highlights. Genetics in renal transplantation: a recent tale of chemokines, enzymes, drugs and HLA. Kuypers, D.R. Pharmacogenomics (2010)
- Skin problems in chronic kidney disease. Kuypers, D.R. Nat. Clin. Pract. Nephrol (2009)
- Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients. Kuypers, D.R., Ekberg, H., Grinyó, J., Nashan, B., Vincenti, F., Snell, P., Mamelok, R.D., Bouw, R.M. Clin. Pharmacokinet (2009)
- Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions. Kuypers, D.R. Drugs. Aging (2009)
- Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients. Kuypers, D.R., de Jonge, H., Naesens, M., Vanrenterghem, Y. Pharmacogenet. Genomics (2008)
- Current target ranges of mycophenolic acid exposure and drug-related adverse events: a 5-year, open-label, prospective, clinical follow-up study in renal allograft recipients. Kuypers, D.R., de Jonge, H., Naesens, M., de Loor, H., Halewijck, E., Dekens, M., Vanrenterghem, Y. Clin. Ther (2008)
- Early clinical assessment of glucose metabolism in renal allograft recipients: diagnosis and prediction of post-transplant diabetes mellitus (PTDM). Kuypers, D.R., Claes, K., Bammens, B., Evenepoel, P., Vanrenterghem, Y. Nephrol. Dial. Transplant. (2008)
- Influence of interactions between immunosuppressive drugs on therapeutic drug monitoring. Kuypers, D.R. Ann. Transplant. (2008)
- Immunosuppressive drug therapy and subclinical acute renal allograft rejection: impact and effect. Kuypers, D.R. Transplantation (2008)
- CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients. Kuypers, D.R., de Jonge, H., Naesens, M., Lerut, E., Verbeke, K., Vanrenterghem, Y. Clin. Pharmacol. Ther. (2007)
- Recurrence of light chain deposit disease after renal allograft transplantation: potential role of rituximab?. Kuypers, D.R., Lerut, E., Claes, K., Evenepoel, P., Vanrenterghem, Y. Transpl. Int. (2007)
- Kidney transplantation: current issues and future prospects. Kuypers, D.R. Acta. Clin. Belg (2007)
- Benefit-risk assessment of sirolimus in renal transplantation. Kuypers, D.R. Drug. Saf (2005)
- Immunosuppressive drug monitoring - what to use in clinical practice today to improve renal graft outcome. Kuypers, D.R. Transpl. Int. (2005)
- A simplified strategy for clinical management of late cytomegalovirus infection after oral ganciclovir prophylaxis in renal recipients. Kuypers, D.R., Claes, K., Evenepoel, P., Maes, B., Vanrenterghem, Y. J. Antimicrob. Chemother. (2005)
- Adjuvant low-dose cidofovir therapy for BK polyomavirus interstitial nephritis in renal transplant recipients. Kuypers, D.R., Vandooren, A.K., Lerut, E., Evenepoel, P., Claes, K., Snoeck, R., Naesens, L., Vanrenterghem, Y. Am. J. Transplant. (2005)
- Drug interaction between mycophenolate mofetil and rifampin: possible induction of uridine diphosphate-glucuronosyltransferase. Kuypers, D.R., Verleden, G., Naesens, M., Vanrenterghem, Y. Clin. Pharmacol. Ther. (2005)
- The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid dose-interval exposure in de novo renal allograft recipients. Kuypers, D.R., Naesens, M., Vermeire, S., Vanrenterghem, Y. Clin. Pharmacol. Ther. (2005)
- Clinical efficacy and toxicity profile of tacrolimus and mycophenolic acid in relation to combined long-term pharmacokinetics in de novo renal allograft recipients. Kuypers, D.R., Claes, K., Evenepoel, P., Maes, B., Vanrenterghem, Y. Clin. Pharmacol. Ther. (2004)
- A prospective proof of concept study of the efficacy of tacrolimus ointment on uraemic pruritus (UP) in patients on chronic dialysis therapy. Kuypers, D.R., Claes, K., Evenepoel, P., Maes, B., Vanrenterghem, Y. Nephrol. Dial. Transplant. (2004)
- Time-related clinical determinants of long-term tacrolimus pharmacokinetics in combination therapy with mycophenolic acid and corticosteroids: a prospective study in one hundred de novo renal transplant recipients. Kuypers, D.R., Claes, K., Evenepoel, P., Maes, B., Coosemans, W., Pirenne, J., Vanrenterghem, Y. Clin. Pharmacokinet (2004)
- The rate of gastric emptying determines the timing but not the extent of oral tacrolimus absorption: simultaneous measurement of drug exposure and gastric emptying by carbon-14-octanoic acid breath test in stable renal allograft recipients. Kuypers, D.R., Claes, K., Evenepoel, P., Maes, B., Vanrenterghem, Y. Drug Metab. Dispos. (2004)
- Calcium channel blockade and preservation of renal graft function in cyclosporine-treated recipients: a prospective randomized placebo-controlled 2-year study. Kuypers, D.R., Neumayer, H.H., Fritsche, L., Budde, K., Rodicio, J.L., Vanrenterghem, Y. Transplantation (2004)
- Time to reach tacrolimus maximum blood concentration,mean residence time, and acute renal allograft rejection: an open-label, prospective, pharmacokinetic study in adult recipients. Kuypers, D.R., Vanrenterghem, Y. Clin. Ther (2004)
- Clinical use of rapamycin in renal allograft recipients identifies its relevant toxicity profile and raises unsolved questions: a single-center experience. Kuypers, D.R., Herelixka, A., Vanrenterghem, Y. Transplant. Proc. (2003)
- The use of an anti-CD25 monoclonal antibody and mycophenolate mofetil enables the use of a low-dose tacrolimus and early withdrawal of steroids in renal transplant recipients. Kuypers, D.R., Evenepoel, P., Maes, B., Coosemans, W., Pirenne, J., Vanrenterghem, Y. Clin. Transplant (2003)
- C3D deposition in peritubular capillaries indicates a variant of acute renal allograft rejection characterized by a worse clinical outcome. Kuypers, D.R., Lerut, E., Evenepoel, P., Maes, B., Vanrenterghem, Y., Van Damme, B. Transplantation (2003)
- Long-term pharmacokinetic study of the novel combination of tacrolimus and sirolimus in de novo renal allograft recipients. Kuypers, D.R., Claes, K., Evenepoel, P., Maes, B., Vanrenterghem, Y. Ther. Drug. Monit (2003)
