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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Dirk Beher

Department of Biochemistry & Molecular Biology

Merck Sharp & Dohme Research Laboratories

The Neuroscience Research Centre

Terlings Park

United Kingdom

[email]@merck.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliation

  • Department of Biochemistry & Molecular Biology, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Terlings Park, United Kingdom. 2001 - 2005

References

  1. Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease. Beher, D., Graham, S.L. Expert. Opin. Investig. Drugs (2005) [Pubmed]
  2. Selected non-steroidal anti-inflammatory drugs and their derivatives target gamma-secretase at a novel site. Evidence for an allosteric mechanism. Beher, D., Clarke, E.E., Wrigley, J.D., Martin, A.C., Nadin, A., Churcher, I., Shearman, M.S. J. Biol. Chem. (2004) [Pubmed]
  3. In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand. Beher, D., Fricker, M., Nadin, A., Clarke, E.E., Wrigley, J.D., Li, Y.M., Culvenor, J.G., Masters, C.L., Harrison, T., Shearman, M.S. Biochemistry (2003) [Pubmed]
  4. Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity. Beher, D., Wrigley, J.D., Owens, A.P., Shearman, M.S. J. Neurochem. (2002) [Pubmed]
  5. Gamma-secretase inhibition. Beher, D., Shearman, M.S. Biochem. Soc. Trans. (2002) [Pubmed]
  6. Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology. Beher, D., Wrigley, J.D., Nadin, A., Evin, G., Masters, C.L., Harrison, T., Castro, J.L., Shearman, M.S. J. Biol. Chem. (2001) [Pubmed]
 
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