Donald E. Lavelle
Department of Medicine
University of Illinois at Chicago
840 S
Wood St
USA
Name/email consistency: high
- S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis). Lavelle, D., Saunthararajah, Y., Vaitkus, K., Singh, M., Banzon, V., Phiasivongsva, P., Redkar, S., Kanekal, S., Bearss, D., Shi, C., Inloes, R., DeSimone, J. J. Transl. Med (2010)
- Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis. Lavelle, D., Chin, J., Vaitkus, K., Redkar, S., Phiasivongsa, P., Tang, C., Will, R., Hankewych, M., Roxas, B., Singh, M., Saunthararajah, Y., Desimone, J. Am. J. Hematol. (2007)
- Developmental changes in DNA methylation and covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin gene promoters in Papio anubis. Lavelle, D., Vaitkus, K., Hankewych, M., Singh, M., DeSimone, J. Blood Cells Mol. Dis. (2006)
- Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis. Lavelle, D., Vaitkus, K., Hankewych, M., Singh, M., DeSimone, J. Exp. Hematol. (2006)
- The molecular mechanism of fetal hemoglobin reactivation. Lavelle, D.E. Semin. Hematol. (2004)
- Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway. Lavelle, D., DeSimone, J., Hankewych, M., Kousnetzova, T., Chen, Y.H. Leuk. Res. (2003)
- Effects of hydroxurea, stem cell factor, and erythropoietin in combination on fetal hemoglobin in the baboon. Lavelle, D., Molokie, R., Ducksworth, J., DeSimone, J. Exp. Hematol. (2001)
- Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression. Lavelle, D., Chen, Y.H., Hankewych, M., DeSimone, J. Am. J. Hematol. (2001)









