Andrea Gaedigk
Division of Pediatric Pharmacology & Medical Toxicology
The Children's Mercy Hospital & Clinics
2401 Gillham Rd
Kansas City
USA
Name/email consistency: high
- CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR. Gaedigk, A., Twist, G.P., Leeder, J.S. Pharmacogenomics (2012)
- Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations. Gaedigk, A., Isidoro-García, M., Pearce, R.E., Sánchez, S., García-Solaesa, V., Lorenzo-Romo, C., Gonzalez-Tejera, G., Corey, S. Eur. J. Clin. Pharmacol. (2010)
- UGT2B17 and SULT1A1 gene copy number variation (CNV) detection by LabChip microfluidic technology. Gaedigk, A., Gaedigk, R., Leeder, J.S. Clin. Chem. Lab. Med. (2010)
- CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction. Gaedigk, A., Fuhr, U., Johnson, C., Bérard, L.A., Bradford, D., Leeder, J.S. Pharmacogenomics (2010)
- Identification of a novel non-functional CYP2D6 allele, CYP2D6*69, in a Caucasian poor metabolizer individual. Gaedigk, A., Frank, D., Fuhr, U. Eur. J. Clin. Pharmacol. (2009)
- The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype. Gaedigk, A., Simon, S.D., Pearce, R.E., Bradford, L.D., Kennedy, M.J., Leeder, J.S. Clin. Pharmacol. Ther. (2008)
- The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements. Gaedigk, A., Coetsee, C. Eur. J. Clin. Pharmacol. (2008)
- Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events. Gaedigk, A., Ndjountché, L., Divakaran, K., Dianne Bradford, L., Zineh, I., Oberlander, T.F., Brousseau, D.C., McCarver, D.G., Johnson, J.A., Alander, S.W., Wayne Riggs, K., Steven Leeder, J. Clin. Pharmacol. Ther. (2007)
- Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype. Gaedigk, A., Eklund, J.D., Pearce, R.E., Leeder, J.S., Alander, S.W., Phillips, M.S., Bradford, L.D., Kennedy, M.J. Clin. Pharmacol. Ther. (2007)
- CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status. Gaedigk, A., Bradford, L.D., Alander, S.W., Leeder, J.S. Drug Metab. Dispos. (2006)
- Variability of CYP2J2 expression in human fetal tissues. Gaedigk, A., Baker, D.W., Totah, R.A., Gaedigk, R., Pearce, R.E., Vyhlidal, C.A., Zeldin, D.C., Leeder, J.S. J. Pharmacol. Exp. Ther. (2006)
- Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans. Gaedigk, A., Bhathena, A., Ndjountché, L., Pearce, R.E., Abdel-Rahman, S.M., Alander, S.W., Bradford, L.D., Rogan, P.K., Leeder, J.S. Pharmacogenomics J. (2005)
- CYP2D7 splice variants in human liver and brain: does CYP2D7 encode functional protein?. Gaedigk, A., Gaedigk, R., Leeder, J.S. Biochem. Biophys. Res. Commun. (2005)
- CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism. Gaedigk, A., Ryder, D.L., Bradford, L.D., Leeder, J.S. Clin. Chem. (2003)
- Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans. Gaedigk, A., Bradford, L.D., Marcucci, K.A., Leeder, J.S. Clin. Pharmacol. Ther. (2002)
- Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations. Gaedigk, A., Casley, W.L., Tyndale, R.F., Sellers, E.M., Jurima-Romet, M., Leeder, J.S. Can. J. Physiol. Pharmacol. (2001)
- Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data. Gaedigk, A., Gotschall, R.R., Forbes, N.S., Simon, S.D., Kearns, G.L., Leeder, J.S. Pharmacogenetics (1999)
- NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations. Gaedigk, A., Tyndale, R.F., Jurima-Romet, M., Sellers, E.M., Grant, D.M., Leeder, J.S. Pharmacogenetics (1998)
