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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

D. Scott Wilbur

Department of Radiation Oncology

University of Washington


Washington 98105



Name/email consistency: high



  • Department of Radiation Oncology, University of Washington, Seattle, Washington 98105, USA. 1996 - 2011


  1. Chemical and radiochemical considerations in radiolabeling with α-emitting radionuclides. Wilbur, D.S. Curr. Radiopharm (2011) [Pubmed]
  2. Design and synthesis of bis-biotin-containing reagents for applications utilizing monoclonal antibody-based pretargeting systems with streptavidin mutants. Wilbur, D.S., Park, S.I., Chyan, M.K., Wan, F., Hamlin, D.K., Shenoi, J., Lin, Y., Wilbur, S.M., Buchegger, F., Pantelias, A., Pagel, J.M., Press, O.W. Bioconjug. Chem. (2010) [Pubmed]
  3. Preparation and in vivo evaluation of radioiodinated closo-decaborate(2-) derivatives to identify structural components that provide low retention in tissues. Wilbur, D.S., Chyan, M.K., Hamlin, D.K., Perry, M.A. Nucl. Med. Biol. (2010) [Pubmed]
  4. Reagents for astatination of biomolecules. 3. Comparison of closo-decaborate(2-) and closo-dodecaborate(2-) moieties as reactive groups for labeling with astatine-211. Wilbur, D.S., Chyan, M.K., Hamlin, D.K., Perry, M.A. Bioconjug. Chem. (2009) [Pubmed]
  5. Streptavidin in antibody pretargeting. 5. chemical modification of recombinant streptavidin for labeling with the alpha-particle-emitting radionuclides 213Bi and 211At. Wilbur, D.S., Hamlin, D.K., Chyan, M.K., Brechbiel, M.W. Bioconjug. Chem. (2008) [Pubmed]
  6. Reagents for astatination of biomolecules. 2. Conjugation of anionic boron cage pendant groups to a protein provides a method for direct labeling that is stable to in vivo deastatination. Wilbur, D.S., Chyan, M.K., Hamlin, D.K., Vessella, R.L., Wedge, T.J., Hawthorne, M.F. Bioconjug. Chem. (2007) [Pubmed]
  7. Biotin reagents for antibody pretargeting. 7. Investigation of chemically inert biotinidase blocking functionalities for synthetic utility. Wilbur, D.S., Hamlin, D.K., Chyan, M.K. Bioconjug. Chem. (2006) [Pubmed]
  8. Reagents for astatination of biomolecules: comparison of the in vivo distribution and stability of some radioiodinated/astatinated benzamidyl and nido-carboranyl compounds. Wilbur, D.S., Chyan, M.K., Hamlin, D.K., Kegley, B.B., Risler, R., Pathare, P.M., Quinn, J., Vessella, R.L., Foulon, C., Zalutsky, M., Wedge, T.J., Hawthorne, M.F. Bioconjug. Chem. (2004) [Pubmed]
  9. Synthesis, radioiodination, and biodistribution of some nido- and closo-monocarbon carborane derivatives. Wilbur, D.S., Hamlin, D.K., Srivastava, R.R., Chyan, M.K. Nucl. Med. Biol. (2004) [Pubmed]
  10. Biotin reagents in antibody pretargeting. 6. Synthesis and in vivo evaluation of astatinated and radioiodinated aryl- and nido-carboranyl-biotin derivatives. Wilbur, D.S., Hamlin, D.K., Chyan, M.K., Kegley, B.B., Quinn, J., Vessella, R.L. Bioconjug. Chem. (2004) [Pubmed]
  11. Streptavidin in antibody pretargeting. 4. Site-directed mutation provides evidence that both arginine and lysine residues are involved in kidney localization. Wilbur, D.S., Hamlin, D.K., Sanderson, J., Lin, Y. Bioconjug. Chem. (2004) [Pubmed]
  12. Streptavidin in antibody pretargeting. 3. Comparison of biotin binding and tissue localization of 1,2-cyclohexanedione and succinic anhydride modified recombinant streptavidin. Wilbur, D.S., Hamlin, D.K., Meyer, D.L., Mallett, R.W., Quinn, J., Vessella, R.L., Press, O.W. Bioconjug. Chem. (2002) [Pubmed]
  13. Biotin reagents for antibody pretargeting. 5. Additional studies of biotin conjugate design to provide biotinidase stability. Wilbur, D.S., Hamlin, D.K., Chyan, M.K., Kegley, B.B., Pathare, P.M. Bioconjug. Chem. (2001) [Pubmed]
  14. Biotin reagents for antibody pretargeting. 4. Selection of biotin conjugates for in vivo application based on their dissociation rate from avidin and streptavidin. Wilbur, D.S., Chyan, M.K., Pathare, P.M., Hamlin, D.K., Frownfelter, M.B., Kegley, B.B. Bioconjug. Chem. (2000) [Pubmed]
  15. Evaluation of biotin-dye conjugates for use in an HPLC assay to assess relative binding of biotin derivatives with avidin and streptavidin. Wilbur, D.S., Pathare, P.M., Hamlin, D.K., Frownfelter, M.B., Kegley, B.B., Leung, W.Y., Gee, K.R. Bioconjug. Chem. (2000) [Pubmed]
  16. Radioiodination of cyanocobalamin conjugates containing hydrophilic linkers: preparation of a radioiodinated cyanocobalamin monomer and two dimers, and assessment of their binding with transcobalamin II. Wilbur, D.S., Pathare, P.M., Hamlin, D.K., Rothenberg, S.P., Quadros, E.V. Bioconjug. Chem. (1999) [Pubmed]
  17. Streptavidin in antibody pretargeting. Comparison of a recombinant streptavidin with two streptavidin mutant proteins and two commercially available streptavidin proteins. Wilbur, D.S., Stayton, P.S., To, R., Buhler, K.R., Klumb, L.A., Hamlin, D.K., Stray, J.E., Vessella, R.L. Bioconjug. Chem. (1998) [Pubmed]
  18. Streptavidin in antibody pretargeting. 2. Evaluation Of methods for decreasing localization of streptavidin to kidney while retaining its tumor binding capacity. Wilbur, D.S., Hamlin, D.K., Buhler, K.R., Pathare, P.M., Vessella, R.L., Stayton, P.S., To, R. Bioconjug. Chem. (1998) [Pubmed]
  19. Biotin reagents for antibody pretargeting. 3. Synthesis, radioiodination, and evaluation of biotinylated starburst dendrimers. Wilbur, D.S., Pathare, P.M., Hamlin, D.K., Buhler, K.R., Vessella, R.L. Bioconjug. Chem. (1998) [Pubmed]
  20. Biotin reagents for antibody pretargeting. Synthesis, radioiodination, and in vitro evaluation of water soluble, biotinidase resistant biotin derivatives. Wilbur, D.S., Hamlin, D.K., Pathare, P.M., Weerawarna, S.A. Bioconjug. Chem. (1997) [Pubmed]
  21. Biotin reagents for antibody pretargeting. 2. Synthesis and in vitro evaluation of biotin dimers and trimers for cross-linking of streptavidin. Wilbur, D.S., Pathare, P.M., Hamlin, D.K., Weerawarna, S.A. Bioconjug. Chem. (1997) [Pubmed]
  22. Antibody fragments in tumor pretargeting. Evaluation of biotinylated Fab' colocalization with recombinant streptavidin and avidin. Wilbur, D.S., Hamlin, D.K., Vessella, R.L., Stray, J.E., Buhler, K.R., Stayton, P.S., Klumb, L.A., Pathare, P.M., Weerawarna, S.A. Bioconjug. Chem. (1996) [Pubmed]
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