John Dunlop
Discovery Neuroscience
Wyeth Research
CN-8000
Princeton
USA
Name/email consistency: high
- Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide). Dunlop, J., Lock, T., Jow, B., Sitzia, F., Grauer, S., Jow, F., Kramer, A., Bowlby, M.R., Randall, A., Kowal, D., Gilbert, A., Comery, T.A., Larocque, J., Soloveva, V., Brown, J., Roncarati, R. J. Pharmacol. Exp. Ther. (2009)
- Turning up the pace of ion channel screening in drug discovery. Dunlop, J. Neuropsychopharmacology (2009)
- Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and pain. Dunlop, J., Vasilyev, D., Lu, P., Cummons, T., Bowlby, M.R. Curr. Pharm. Des. (2009)
- High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology. Dunlop, J., Bowlby, M., Peri, R., Vasilyev, D., Arias, R. Nat. Rev. Drug. Discov (2008)
- Ion channel screening. Dunlop, J., Bowlby, M., Peri, R., Tawa, G., LaRocque, J., Soloveva, V., Morin, J. Comb. Chem. High Throughput Screen. (2008)
- In vitro screening strategies for nicotinic receptor ligands. Dunlop, J., Roncarati, R., Jow, B., Bothmann, H., Lock, T., Kowal, D., Bowlby, M., Terstappen, G.C. Biochem. Pharmacol. (2007)
- Glutamate-based therapeutic approaches: targeting the glutamate transport system. Dunlop, J. Curr. Opin. Pharmacol (2006)
- Ligands targeting the excitatory amino acid transporters (EAATs). Dunlop, J., Butera, J.A. Curr. Top. Med. Chem (2006)
- Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications. Dunlop, J., Marquis, K.L., Lim, H.K., Leung, L., Kao, J., Cheesman, C., Rosenzweig-Lipson, S. CNS. Drug. Rev (2006)
- WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity. Dunlop, J., Sabb, A.L., Mazandarani, H., Zhang, J., Kalgaonker, S., Shukhina, E., Sukoff, S., Vogel, R.L., Stack, G., Schechter, L., Harrison, B.L., Rosenzweig-Lipson, S. J. Pharmacol. Exp. Ther. (2005)
- Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2. Dunlop, J., McIlvain, H.B., Carrick, T.A., Jow, B., Lu, Q., Kowal, D., Lin, S., Greenfield, A., Grosanu, C., Fan, K., Petroski, R., Williams, J., Foster, A., Butera, J. Mol. Pharmacol. (2005)
- WAY-855 (3-amino-tricyclo[2.2.1.02.6]heptane-1,3-dicarboxylic acid): a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake. Dunlop, J., Eliasof, S., Stack, G., McIlvain, H.B., Greenfield, A., Kowal, D., Petroski, R., Carrick, T. Br. J. Pharmacol. (2003)
