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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Erik De Clercq

Rega Institute for Medical Research


Minderbroedersstraat 10

B-3000 Leuven



Name/email consistency: high



  • Rega Institute for Medical Research, K.U.Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. 1998 - 2011
  • Division of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, K.U. Leuven, Belgium. 2001 - 2005


  1. The next ten stories on antiviral drug discovery (part E): advents, advances, and adventures. De Clercq, E. Med. Res. Rev (2011) [Pubmed]
  2. Interferon and its inducers--a never-ending story: "old" and "new" data in a new perspective. De Clercq, E. J. Infect. Dis. (2006) [Pubmed]
  3. (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). De Clercq, E. Med. Res. Rev (2005) [Pubmed]
  4. New approaches toward anti-HIV chemotherapy. De Clercq, E. J. Med. Chem. (2005) [Pubmed]
  5. Antiviral drug discovery and development: where chemistry meets with biomedicine. De Clercq, E. Antiviral Res. (2005) [Pubmed]
  6. Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines. De Clercq, E., Andrei, G., Balzarini, J., Leyssen, P., Naesens, L., Neyts, J., Pannecouque, C., Snoeck, R., Ying, C., Hocková, D., Holý, A. Nucleosides. Nucleotides. Nucleic. Acids (2005) [Pubmed]
  7. Acyclic nucleoside phosphonates: a key class of antiviral drugs. De Clercq, E., Holý, A. Nat. Rev. Drug. Discov (2005) [Pubmed]
  8. Nucleoside analogues exerting antiviral activity through a non-nucleoside mechanism. De Clercq, E. Nucleosides. Nucleotides. Nucleic. Acids (2004) [Pubmed]
  9. Antiviral drugs in current clinical use. De Clercq, E. J. Clin. Virol. (2004) [Pubmed]
  10. HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches. De Clercq, E. Int. J. Biochem. Cell Biol. (2004) [Pubmed]
  11. Therapeutic potential of nucleoside/nucleotide analogues against poxvirus infections. De Clercq, E., Neyts, J. Rev. Med. Virol. (2004) [Pubmed]
  12. Antivirals and antiviral strategies. De Clercq, E. Nat. Rev. Microbiol. (2004) [Pubmed]
  13. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. De Clercq, E. Biochem. Pharmacol. (2004) [Pubmed]
  14. Non-nucleoside reverse transcriptase inhibitors (NNRTIs): past, present, and future. De Clercq, E. Chem. Biodivers. (2004) [Pubmed]
  15. Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues. De Clercq, E. Med. Res. Rev (2003) [Pubmed]
  16. The bicyclam AMD3100 story. De Clercq, E. Nat. Rev. Drug. Discov (2003) [Pubmed]
  17. Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections. De Clercq, E. Clin. Microbiol. Rev. (2003) [Pubmed]
  18. Cidofovir in the treatment of poxvirus infections. De Clercq, E. Antiviral Res. (2002) [Pubmed]
  19. Strategies in the design of antiviral drugs. De Clercq, E. Nat. Rev. Drug. Discov (2002) [Pubmed]
  20. New anti-HIV agents and targets. De Clercq, E. Med. Res. Rev (2002) [Pubmed]
  21. Highlights in the development of new antiviral agents. De Clercq, E. Mini. Rev. Med. Chem (2002) [Pubmed]
  22. 2001 ASPET Otto Krayer Award Lecture. Molecular targets for antiviral agents. De Clercq, E. J. Pharmacol. Exp. Ther. (2001) [Pubmed]
  23. Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections. De Clercq, E. Clin. Microbiol. Rev. (2001) [Pubmed]
  24. New developments in anti-HIV chemotherapy. De Clercq, E. Farmaco (2001) [Pubmed]
  25. Antiviral drugs: current state of the art. De Clercq, E. J. Clin. Virol. (2001) [Pubmed]
  26. New developments in anti-HIV chemotherapy. De Clercq, E. Curr. Med. Chem. (2001) [Pubmed]
  27. Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists. De Clercq, E., Schols, D. Antivir. Chem. Chemother. (2001) [Pubmed]
  28. Hamao Umezawa Memorial Award Lecture: "An Odyssey in the Viral Chemotherapy Field". De Clercq, E. Int. J. Antimicrob. Agents (2001) [Pubmed]
  29. Inhibition of HIV infection by bicyclams, highly potent and specific CXCR4 antagonists. De Clercq, E. Mol. Pharmacol. (2000) [Pubmed]
  30. Perspectives for the treatment of hepatitis B virus infections. De Clercq, E. Int. J. Antimicrob. Agents (1999) [Pubmed]
  31. The emerging role of fusion inhibitors in HIV infection. De Clercq, E. Drugs. R. D (1999) [Pubmed]
  32. Carbocyclic adenosine analogues as S-adenosylhomocysteine hydrolase inhibitors and antiviral agents: recent advances. De Clercq, E. Nucleosides. Nucleotides (1998) [Pubmed]
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