Mark D. Erion
Department of Medicinal Chemistry
Metabasis Therapeutics
Inc., 11119 North Torrey Pines Road
La Jolla
USA
Name/email consistency: high
- Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity. Erion, M.D., Dang, Q., Reddy, M.R., Kasibhatla, S.R., Huang, J., Lipscomb, W.N., van Poelje, P.D. J. Am. Chem. Soc. (2007)
- Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index. Erion, M.D., Cable, E.E., Ito, B.R., Jiang, H., Fujitaki, J.M., Finn, P.D., Zhang, B.H., Hou, J., Boyer, S.H., van Poelje, P.D., Linemeyer, D.L. Proc. Natl. Acad. Sci. U.S.A. (2007)
- HepDirect prodrugs for targeting nucleotide-based antiviral drugs to the liver. Erion, M.D., Bullough, D.A., Lin, C.C., Hong, Z. Curr. Opin. Investig. Drugs (2006)
- Liver-targeted drug delivery using HepDirect prodrugs. Erion, M.D., van Poelje, P.D., Mackenna, D.A., Colby, T.J., Montag, A.C., Fujitaki, J.M., Linemeyer, D.L., Bullough, D.A. J. Pharmacol. Exp. Ther. (2005)
- MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes. Erion, M.D., van Poelje, P.D., Dang, Q., Kasibhatla, S.R., Potter, S.C., Reddy, M.R., Reddy, K.R., Jiang, T., Lipscomb, W.N. Proc. Natl. Acad. Sci. U.S.A. (2005)











