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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Frank J. Gonzalez

National Cancer Research

National Institutes of Health


MD 20892



Name/email consistency: high



  • National Cancer Research, National Institutes of Health, Bethesda, MD 20892, USA. 1995 - 2008
  • Division of Basic Sciences, National Cancer Institute, Building 37, Room 3E-24, USA. 2001 - 2006
  • Building 37, Room 3E-24, Laboratory of Metabolism, National Cancer Institute, USA. 2003


  1. PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators. Gonzalez, F.J., Shah, Y.M. Toxicology (2008) [Pubmed]
  2. CYP3A4 and pregnane X receptor humanized mice. Gonzalez, F.J. J. Biochem. Mol. Toxicol. (2007) [Pubmed]
  3. Animal models for human risk assessment: the peroxisome proliferator-activated receptor alpha-humanized mouse. Gonzalez, F.J. Nutr. Rev. (2007) [Pubmed]
  4. The 2006 Bernard B. Brodie Award Lecture. Cyp2e1. Gonzalez, F.J. Drug Metab. Dispos. (2007) [Pubmed]
  5. Cytochrome P450 and xenobiotic receptor humanized mice. Gonzalez, F.J., Yu, A.M. Annu. Rev. Pharmacol. Toxicol. (2006) [Pubmed]
  6. Role of HNF4alpha in the superinduction of the IL-1beta-activated iNOS gene by oxidative stress. Gonzalez, F.J. Biochem. J. (2006) [Pubmed]
  7. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Gonzalez, F.J. Mutat. Res. (2005) [Pubmed]
  8. Cytochrome P450 humanised mice. Gonzalez, F.J. Hum. Genomics (2004) [Pubmed]
  9. Study of P450 function using gene knockout and transgenic mice. Gonzalez, F.J., Kimura, S. Arch. Biochem. Biophys. (2003) [Pubmed]
  10. Role of gene knockout and transgenic mice in the study of xenobiotic metabolism. Gonzalez, F.J. Drug Metab. Rev. (2003) [Pubmed]
  11. The peroxisome proliferator-activated receptor alpha (PPARalpha): role in hepatocarcinogenesis. Gonzalez, F.J. Mol. Cell. Endocrinol. (2002) [Pubmed]
  12. Transgenic models in xenobiotic metabolism and toxicology. Gonzalez, F.J. Toxicology (2002) [Pubmed]
  13. The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis. Gonzalez, F.J. Toxicol. Lett. (2001) [Pubmed]
  14. Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice. Gonzalez, F.J., Kimura, S. Mutat. Res. (2001) [Pubmed]
  15. Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis. Gonzalez, F.J., Kimura, S. Cancer Lett. (1999) [Pubmed]
  16. The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption. Gonzalez, F.J. Toxicol. Lett. (1998) [Pubmed]
  17. Mechanism of action of the nongenotoxic peroxisome proliferators: role of the peroxisome proliferator-activator receptor alpha. Gonzalez, F.J., Peters, J.M., Cattley, R.C. J. Natl. Cancer Inst. (1998) [Pubmed]
  18. The aryl hydrocarbon receptor: studies using the AHR-null mice. Gonzalez, F.J., Fernandez-Salguero, P. Drug Metab. Dispos. (1998) [Pubmed]
  19. The role of peroxisome proliferator activated receptor alpha in peroxisome proliferation, physiological homeostasis, and chemical carcinogenesis. Gonzalez, F.J. Adv. Exp. Med. Biol. (1997) [Pubmed]
  20. Xenobiotic receptor knockout mice. Gonzalez, F.J., Fernandez-Salguero, P., Lee, S.S., Pineau, T., Ward, J.M. Toxicol. Lett. (1995) [Pubmed]
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