Florian Nachon
Cellule Enzymologie
Département de Toxicologie
Institut de Recherche Biomédicale des Armées-CRSSA
24 avenue des Maquis du Grésivaudan
France
Name/email consistency: high
- X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger. Nachon, F., Carletti, E., Wandhammer, M., Nicolet, Y., Schopfer, L.M., Masson, P., Lockridge, O. Biochem. J. (2011)
- Aging mechanism of butyrylcholinesterase inhibited by an N-methyl analogue of tabun: implications of the trigonal-bipyramidal transition state rearrangement for the phosphylation or reactivation of cholinesterases. Nachon, F., Carletti, E., Worek, F., Masson, P. Chem. Biol. Interact. (2010)
- Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging. Nachon, F., Asojo, O.A., Borgstahl, G.E., Masson, P., Lockridge, O. Biochemistry (2005)
- Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization. Nachon, F., Nicolet, Y., Viguié, N., Masson, P., Fontecilla-Camps, J.C., Lockridge, O. Eur. J. Biochem. (2002)