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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Frank Seela

Laboratory of Bioorganic Chemistry and Chemical Biology

Center for Nanotechnology

Heisenbergstrasse 11

48149

Germany

[email]@uni-osnabrueck.de

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, 48149, Germany. 2007 - 2012
  • Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Barbarastrasse 7, Germany. 2001 - 2009

References

  1. Parallel-stranded DNA: Enhancing duplex stability by the 'G-clamp' and a pyrrolo-dC derivative. Ming, X., Ding, P., Leonard, P., Budow, S., Seela, F. Org. Biomol. Chem. (2012) [Pubmed]
  2. 1,N6-etheno-2'-deoxytubercidin hemihydrate. Seela, F., Ding, P., Leonard, P., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2011) [Pubmed]
  3. Azide-alkyne "click" conjugation of 8-aza-7-deazaadenine-DNA: synthesis, duplex stability, and fluorogenic dye labeling. Seela, F., Pujari, S.S. Bioconjug. Chem. (2010) [Pubmed]
  4. "Double click" reaction on 7-deazaguanine DNA: synthesis and excimer fluorescence of nucleosides and oligonucleotides with branched side chains decorated with proximal pyrenes. Seela, F., Ingale, S.A. J. Org. Chem. (2010) [Pubmed]
  5. A toyocamycin analogue with the sugar moiety in a syn conformation. Seela, F., Ingale, S.A., Leonard, P., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2009) [Pubmed]
  6. 8-Aza-7-deazaguanine nucleosides and oligonucleotides with octadiynyl side chains: synthesis, functionalization by the azide-alkyne 'click' reaction and nucleobase specific fluorescence quenching of coumarin dye conjugates. Seela, F., Xiong, H., Leonard, P., Budow, S. Org. Biomol. Chem. (2009) [Pubmed]
  7. 8-Aza-2'-deoxyguanosine: base pairing, mismatch discrimination and nucleobase anion fluorescence sensing in single-stranded and duplex DNA. Seela, F., Jiang, D., Xu, K. Org. Biomol. Chem. (2009) [Pubmed]
  8. 7-Fluorotubercidin: a halogenated derivative of a naturally occurring nucleoside antimetabolite. Seela, F., Ming, X., Budow, S., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2008) [Pubmed]
  9. Pyrrolo-dC oligonucleotides bearing alkynyl side chains with terminal triple bonds: synthesis, base pairing and fluorescent dye conjugates prepared by the azide-alkyne "click" reaction. Seela, F., Sirivolu, V.R. Org. Biomol. Chem. (2008) [Pubmed]
  10. Modification of DNA with octadiynyl side chains: synthesis, base pairing, and formation of fluorescent coumarin dye conjugates of four nucleobases by the alkyne--azide "click" reaction. Seela, F., Sirivolu, V.R., Chittepu, P. Bioconjug. Chem. (2008) [Pubmed]
  11. Mismatch formation in solution and on DNA microarrays: how modified nucleosides can overcome shortcomings of imperfect hybridization caused by oligonucleotide composition and base pairing. Seela, F., Budow, S. Mol. Biosyst (2008) [Pubmed]
  12. 7-Deaza-2'-deoxyinosine: a nucleoside showing ambiguous base-pairing properties against the four canonical DNA constituents. Seela, F., Ming, X., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2008) [Pubmed]
  13. 2'-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine. Seela, F., Ming, X. Org. Biomol. Chem. (2008) [Pubmed]
  14. The 7-bromo derivative of 2-amino-2'-deoxytubercidin fluorinated at the sugar moiety. Seela, F., Ding, P., Peng, X., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2007) [Pubmed]
  15. 2'-Deoxy-5-propynylcytidine: a nucleoside forming two solid-state conformations. Seela, F., Budow, S., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2007) [Pubmed]
  16. Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism. Seela, F., Xu, K. Org. Biomol. Chem. (2007) [Pubmed]
  17. Oligonucleotides containing 6-aza-2'-deoxyuridine: synthesis, nucleobase protection, pH-dependent duplex stability, and metal-DNA formation. Seela, F., Chittepu, P. J. Org. Chem. (2007) [Pubmed]
  18. pH-dependent assembly of DNA-gold nanoparticles based on the i-motif. Seela, F., Budow, S. Nucleosides. Nucleotides. Nucleic. Acids (2007) [Pubmed]
  19. 2'-Deoxyimmunosine: a thiazolo[4,5-d]pyrimidine nucleoside adopting the syn conformation. Seela, F., Ming, X., Budow, S., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2007) [Pubmed]
  20. Oligonucleotides forming an i-motif: the pH-dependent assembly of individual strands and branched structures containing 2'-deoxy-5-propynylcytidine. Seela, F., Budow, S., Leonard, P. Org. Biomol. Chem. (2007) [Pubmed]
  21. 6-Aza-2'-deoxyuridine and N(3)-anisoyl-6-aza-2'-deoxyuridine. Seela, F., Chittepu, P., He, Y., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2007) [Pubmed]
  22. DNA containing side chains with terminal triple bonds: Base-pair stability and functionalization of alkynylated pyrimidines and 7-deazapurines. Seela, F., Sirivolu, V.R. Chem. Biodivers. (2006) [Pubmed]
  23. 4-Amino-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine: a bis-fluorinated analogue of 2'-deoxytubercidin. Seela, F., Chittepu, P., Eickmeier, H. Acta. Crystallogr. C (2006) [Pubmed]
  24. 2-Amino-7-chloro-2'-deoxytubercidin. Seela, F., Peng, X., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2006) [Pubmed]
  25. pH-Independent triplex formation: hairpin DNA containing isoguanine or 9-deaza-9-propynylguanine in place of protonated cytosine. Seela, F., Shaikh, K.I. Org. Biomol. Chem. (2006) [Pubmed]
  26. 2'-Deoxy-7-propynyl-7-deazaadenosine: a DNA duplex-stabilizing nucleoside. Seela, F., Shaikh, K.I., Budow, S., Eickmeier, H. Acta. Crystallogr. C (2006) [Pubmed]
  27. 7-Functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose. Seela, F., Peng, X. J. Org. Chem. (2006) [Pubmed]
  28. Progress in 7-deazapurine - pyrrolo[2,3-d]pyrimidine - ribonucleoside synthesis. Seela, F., Peng, X. Curr. Top. Med. Chem (2006) [Pubmed]
  29. 7-Vinyl-8-aza-7-deaza-2'-deoxyadenosine monohydrate. Seela, F., Zhang, Y., Xu, K., Eickmeier, H. Acta. Crystallogr. C (2005) [Pubmed]
  30. 3-Bromo-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine: a nucleoside which strongly enhances DNA duplex stability. Seela, F., Sirivolu, V.R., He, J., Eickmeier, H. Acta. Crystallogr. C (2005) [Pubmed]
  31. 7-Deaza-2'-deoxyguanosine. Seela, F., Shaikh, K.I., Eickmeier, H. Acta. Crystallogr. C (2005) [Pubmed]
  32. Base-pairing, tautomerism, and mismatch discrimination of 7-halogenated 7-deaza-2'-deoxyisoguanosine: oligonucleotide duplexes with parallel and antiparallel chain orientation. Seela, F., Peng, X., Li, H. J. Am. Chem. Soc. (2005) [Pubmed]
  33. 2'-Deoxy-5-fluorotubercidin. Seela, F., Xu, K., Eickmeier, H. Acta. Crystallogr. C (2005) [Pubmed]
  34. 8-Aza-7-deaza-2'-deoxy-2-(methylsulfanyl)adenosine. Seela, F., Jawalekar, A.M., Budow, S., Eickmeier, H. Acta. Crystallogr. C (2005) [Pubmed]
  35. Stabilization of tandem dG-dA base pairs in DNA-hairpins: replacement of the canonical bases by 7-deaza-7-propynylpurines. Seela, F., Budow, S., Shaikh, K.I., Jawalekar, A.M. Org. Biomol. Chem. (2005) [Pubmed]
  36. Oligonucleotides containing pyrazolo[3,4-d]pyrimidines: 8-Aza-7-deazaadenines with bulky substituents in the 2- or 7-position. Seela, F., Jawalekar, A.M., Sun, L., Leonard, P. Nucleosides. Nucleotides. Nucleic. Acids (2005) [Pubmed]
  37. Regioisomeric 4-nitroindazole N1- and N2-(beta-D-ribonucleosides). Seela, F., Peng, X., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2004) [Pubmed]
  38. Regioselective synthesis of indazole N1- and N2-(beta-D-ribonucleosides). Seela, F., Peng, X. Nucleosides. Nucleotides. Nucleic. Acids (2004) [Pubmed]
  39. 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-4-nitro-1H-indazole. Seela, F., Jawalekar, A.M., Eickmeier, H. Acta. Crystallogr. C (2004) [Pubmed]
  40. Pyrazolo[3,4-d][1,2,3]triazine DNA: synthesis and base pairing of 7-deaza-2,8-diaza-2'-deoxyadenosine. Seela, F., Lindner, M., Glaçon, V., Lin, W. J. Org. Chem. (2004) [Pubmed]
  41. 7-Deaza-2'-deoxy-7-propynylguanosine. Seela, F., Shaikh, K., Eickmeier, H. Acta. Crystallogr. C (2004) [Pubmed]
  42. 6-Aza-2'-deoxy-2'-arabinofluorouridine, a 2'-deoxyribonucleoside with an N-sugar conformation in the solid state and in solution. Seela, F., Chittepu, P., He, J., Eickmeier, H. Acta. Crystallogr. C (2004) [Pubmed]
  43. 6-aza-2'-deoxyisocytidine: synthesis, properties of oligonucleotides, and base-pair stability adjustment of DNA with parallel strand orientation. Seela, F., He, Y. J. Org. Chem. (2003) [Pubmed]
  44. 5-Methyl-6-aza-2'-deoxyisocytidine. Seela, F., He, Y., Eickmeier, H. Acta. Crystallogr. C (2003) [Pubmed]
  45. Synthesis and properties of halogenated 7-deaza-2'-deoxyxanthosine and protected derivatives for oligonucleotide synthesis. Seela, F., Shaikh, K., Wiglenda, T. Nucleosides. Nucleotides. Nucleic. Acids (2003) [Pubmed]
  46. The base pairing properties of 8-aza-7-deaza-2'-deoxyisoguanosine and 7-halogenated derivatives in oligonucleotide duplexes with parallel and antiparallel chain orientation. Seela, F., Kröschel, R. Nucleic Acids Res. (2003) [Pubmed]
  47. Oligonucleotide duplexes containing N8-glycosylated 8-aza-7-deazaguanine and self-assembly of 8-aza-7-deazapurines on the nucleoside and the oligomeric level. Seela, F., Kröschel, R. Org. Biomol. Chem. (2003) [Pubmed]
  48. The alpha-D anomer of 5-aza-7-deaza-2'-deoxyguanosine. Seela, F., Rosemeyer, H., Melenewski, A., Heithoff, E.M., Eickmeier, H., Reuter, H. Acta. Crystallogr. C (2002) [Pubmed]
  49. The C(8)-(2'-deoxy-beta-D-ribofuranoside) of 7-deazaguanine: synthesis and base pairing of oligonucleotides with unusually linked nucleobases. Seela, F., Debelak, H. J. Org. Chem. (2001) [Pubmed]
  50. Quadruplex and pentaplex self-assemblies of oligonucleotides containing short runs of 8-aza-7-deaza-2'-deoxyisoguanosine or 2'-deoxyisoguanosine. Seela, F., Kröschel, R. Bioconjug. Chem. (2001) [Pubmed]
 
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