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Akiyoshi Ohtake

Applied Pharmacology Research Laboratories

Drug Discovery Research

Astellas Pharma Inc.




Name/email consistency: high



  • Applied Pharmacology Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., Tsukuba-shi, Japan. 2007 - 2010
  • Pharmacology Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co. Ltd, 21 Miyukigaoka, Japan. 2006


  1. The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: ameliorative effect of solifenacin succinate (Vesicare), a bladder-selective antimuscarinic agent, on overactive bladder symptoms, especially urgency episodes. Ohtake, A., Sato, S., Sasamata, M., Miyata, K. J. Pharmacol. Sci. (2010) [Pubmed]
  2. Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents. Ohtake, A., Saitoh, C., Yuyama, H., Ukai, M., Okutsu, H., Noguchi, Y., Hatanaka, T., Suzuki, M., Sato, S., Sasamata, M., Miyata, K. Biol. Pharm. Bull. (2007) [Pubmed]
  3. Effects of tamsulosin on resting urethral pressure and arterial blood pressure in anaesthetized female dogs. Ohtake, A., Sato, S., Sasamata, M., Miyata, K. J. Pharm. Pharmacol. (2006) [Pubmed]
  4. Effect of tamsulosin on spontaneous bladder contraction in conscious rats with bladder outlet obstruction: comparison with effect on intraurethral pressure. Ohtake, A., Ukai, M., Saitoh, C., Sonoda, R., Noguchi, Y., Okutsu, H., Yuyama, H., Sato, S., Sasamata, M., Miyata, K. Eur. J. Pharmacol. (2006) [Pubmed]
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