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Giancarlo Aldini

Dipartimento di Scienze Farmaceutiche " Pietro Pratesi"

University of Milan Via Mangiagalli 25

20133 Milan

Italy

[email]@unimi.it

Name/email consistency: high

 
 
 
 
 
 
 

Affiliation

  • Dipartimento di Scienze Farmaceutiche " Pietro Pratesi", University of Milan Via Mangiagalli 25, 20133 Milan, Italy. 2002 - 2011

References

  1. Advanced analytical strategies for recombinant therapeutic proteins. Aldini, G. Curr. Pharm. Biotechnol (2011) [Pubmed]
  2. The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats. Aldini, G., Orioli, M., Rossoni, G., Savi, F., Braidotti, P., Vistoli, G., Yeum, K.J., Negrisoli, G., Carini, M. J. Cell. Mol. Med. (2011) [Pubmed]
  3. A tandem MS precursor-ion scan approach to identify variable covalent modification of albumin Cys34: a new tool for studying vascular carbonylation. Aldini, G., Regazzoni, L., Orioli, M., Rimoldi, I., Facino, R.M., Carini, M. J. Mass. Spectrom (2008) [Pubmed]
  4. Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species? Aldini, G., Vistoli, G., Regazzoni, L., Gamberoni, L., Facino, R.M., Yamaguchi, S., Uchida, K., Carini, M. Chem. Res. Toxicol. (2008) [Pubmed]
  5. Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls. Aldini, G., Dalle-Donne, I., Facino, R.M., Milzani, A., Carini, M. Med. Res. Rev (2007) [Pubmed]
  6. Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement. Aldini, G., Carini, M., Vistoli, G., Shibata, T., Kusano, Y., Gamberoni, L., Dalle-Donne, I., Milzani, A., Uchida, K. Biochemistry (2007) [Pubmed]
  7. Alpha,beta-unsaturated aldehydes adducts to actin and albumin as potential biomarkers of carbonylation damage. Aldini, G., Orioli, M., Carini, M. Redox Rep. (2007) [Pubmed]
  8. Effects of UVB radiation on 4-hydroxy-2-trans-nonenal metabolism and toxicity in human keratinocytes. Aldini, G., Granata, P., Marinello, C., Beretta, G., Carini, M., Facino, R.M. Chem. Res. Toxicol. (2007) [Pubmed]
  9. Mass spectrometric characterization of covalent modification of human serum albumin by 4-hydroxy-trans-2-nonenal. Aldini, G., Gamberoni, L., Orioli, M., Beretta, G., Regazzoni, L., Maffei Facino, R., Carini, M. J. Mass. Spectrom (2006) [Pubmed]
  10. Electron spin resonance and chemiluminescence analyses to elucidate the vasodilating mechanism of sodium nitroprusside. Aldini, G., Pirrone, F., Albertini, M., Orioli, M., Piccoli, A., Mazzola, S., Clement, M.G., Carini, M. Mol. Pharmacol. (2006) [Pubmed]
  11. Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction. Aldini, G., Dalle-Donne, I., Vistoli, G., Maffei Facino, R., Carini, M. J. Mass. Spectrom (2005) [Pubmed]
  12. Carnosine and related dipeptides as quenchers of reactive carbonyl species: from structural studies to therapeutic perspectives. Aldini, G., Facino, R.M., Beretta, G., Carini, M. Biofactors (2005) [Pubmed]
  13. Profiling histidine-containing dipeptides in rat tissues by liquid chromatography/electrospray ionization tandem mass spectrometry. Aldini, G., Orioli, M., Carini, M., Maffei Facino, R. J. Mass. Spectrom (2004) [Pubmed]
  14. Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection. Aldini, G., Carini, M., Piccoli, A., Rossoni, G., Facino, R.M. Life Sci. (2003) [Pubmed]
  15. Detoxification of 4-hydroxynonenal (HNE) in keratinocytes: characterization of conjugated metabolites by liquid chromatography/electrospray ionization tandem mass spectrometry. Aldini, G., Granata, P., Orioli, M., Santaniello, E., Carini, M. J. Mass. Spectrom (2003) [Pubmed]
  16. Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study. Aldini, G., Carini, M., Orioli, M., Facino, R.M., Wenk, G.L. Life Sci. (2002) [Pubmed]
  17. Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?. Aldini, G., Carini, M., Beretta, G., Bradamante, S., Facino, R.M. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  18. Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle. Aldini, G., Granata, P., Carini, M. J. Mass. Spectrom (2002) [Pubmed]
 
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