Gregg L. Semenza
Vascular Program
Institute for Cell Engineering
Department of Pediatrics
Johns Hopkins University School of Medicine
USA
Name/email consistency: high
- Molecular mechanisms mediating metastasis of hypoxic breast cancer cells. Semenza, G.L. Trends. Mol. Med (2012)
- The role of hypoxia-inducible factors in oxygen sensing by the carotid body. Semenza, G.L., Prabhakar, N.R. Adv. Exp. Med. Biol. (2012)
- Hypoxia. Cross talk between oxygen sensing and the cell cycle machinery. Semenza, G.L. Am. J. Physiol., Cell Physiol. (2011)
- Vascular responses to hypoxia and ischemia. Semenza, G.L. Arterioscler. Thromb. Vasc. Biol. (2010)
- Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Semenza, G.L. Oncogene (2010)
- Oxygen homeostasis. Semenza, G.L. Wiley. Interdiscip. Rev. Syst. Biol. Med (2010)
- HIF-1: upstream and downstream of cancer metabolism. Semenza, G.L. Curr. Opin. Genet. Dev. (2010)
- Regulation of cancer cell metabolism by hypoxia-inducible factor 1. Semenza, G.L. Semin. Cancer Biol. (2009)
- Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Semenza, G.L. Physiology. (Bethesda) (2009)
- Regulation of vascularization by hypoxia-inducible factor 1. Semenza, G.L. Ann. N. Y. Acad. Sci. (2009)
- HIF-1 inhibitors for cancer therapy: from gene expression to drug discovery. Semenza, G.L. Curr. Pharm. Des. (2009)
- Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis. Semenza, G.L. Blood (2009)
- Tumor metabolism: cancer cells give and take lactate. Semenza, G.L. J. Clin. Invest. (2008)
- O2 sensing: only skin deep? Semenza, G.L. Cell (2008)
- Hypoxia-inducible factor 1 and cancer pathogenesis. Semenza, G.L. IUBMB. Life (2008)
- Mitochondrial autophagy: life and breath of the cell. Semenza, G.L. Autophagy (2008)
- Does loss of CD151 expression promote the metastasis of hypoxic colon cancer cells?. Semenza, G.L. Clin. Cancer Res. (2008)
- Regulation of tissue perfusion in mammals by hypoxia-inducible factor 1. Semenza, G.L. Exp. Physiol. (2007)
- Life with oxygen. Semenza, G.L. Science (2007)
- HIF-1 mediates the Warburg effect in clear cell renal carcinoma. Semenza, G.L. J. Bioenerg. Biomembr. (2007)
- Hypoxia-inducible factor 1 (HIF-1) pathway. Semenza, G.L. Sci. STKE (2007)
- Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Semenza, G.L. Biochem. J. (2007)
- HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia. Semenza, G.L., Prabhakar, N.R. Antioxid. Redox Signal. (2007)
- Hypoxia and cancer. Semenza, G.L. Cancer Metastasis Rev. (2007)
- Vasculogenesis, angiogenesis, and arteriogenesis: mechanisms of blood vessel formation and remodeling. Semenza, G.L. J. Cell. Biochem. (2007)
- Evaluation of HIF-1 inhibitors as anticancer agents. Semenza, G.L. Drug Discov. Today (2007)
- Hypoxia and human disease-and the Journal of Molecular Medicine. Semenza, G.L. J. Mol. Med. (2007)
- Development of novel therapeutic strategies that target HIF-1. Semenza, G.L. Expert Opin. Ther. Targets (2006)
- Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. Semenza, G.L. Exp. Physiol. (2006)
- Pulmonary vascular responses to chronic hypoxia mediated by hypoxia-inducible factor 1. Semenza, G.L. Proc. Am. Thorac. Soc (2005)
- New insights into nNOS regulation of vascular homeostasis. Semenza, G.L. J. Clin. Invest. (2005)
- Involvement of hypoxia-inducible factor 1 in pulmonary pathophysiology. Semenza, G.L. Chest (2005)
- Intratumoral hypoxia, radiation resistance, and HIF-1. Semenza, G.L. Cancer. Cell (2004)
- Hydroxylation of HIF-1: oxygen sensing at the molecular level. Semenza, G.L. Physiology. (Bethesda) (2004)
- Angiogenesis in ischemic and neoplastic disorders. Semenza, G.L. Annu. Rev. Med. (2003)
- Targeting HIF-1 for cancer therapy. Semenza, G.L. Nat. Rev. Cancer (2003)
- HIF-1 and tumor progression: pathophysiology and therapeutics. Semenza, G.L. Trends. Mol. Med (2002)
- Physiology meets biophysics: visualizing the interaction of hypoxia-inducible factor 1 alpha with p300 and CBP. Semenza, G.L. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Signal transduction to hypoxia-inducible factor 1. Semenza, G. Biochem. Pharmacol. (2002)
- HIF-1 and mechanisms of hypoxia sensing. Semenza, G.L. Curr. Opin. Cell Biol. (2001)
- Hypoxia-inducible factor 1: control of oxygen homeostasis in health and disease. Semenza, G.L. Pediatr. Res. (2001)
- Regulation of hypoxia-induced angiogenesis: a chaperone escorts VEGF to the dance. Semenza, G.L. J. Clin. Invest. (2001)
- Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Semenza, G.L. Trends. Mol. Med (2001)
- HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Semenza, G.L. Cell (2001)
- Expression of hypoxia-inducible factor 1: mechanisms and consequences. Semenza, G.L. Biochem. Pharmacol. (2000)
- HIF-1: mediator of physiological and pathophysiological responses to hypoxia. Semenza, G.L. J. Appl. Physiol. (2000)
- Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Semenza, G.L. Crit. Rev. Biochem. Mol. Biol. (2000)
- HIF-1 and human disease: one highly involved factor. Semenza, G.L. Genes Dev. (2000)
- Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1. Semenza, G.L. J. Clin. Invest. (2000)
- HIF-1: using two hands to flip the angiogenic switch. Semenza, G.L. Cancer Metastasis Rev. (2000)
- Oxygen-regulated transcription factors and their role in pulmonary disease. Semenza, G.L. Respir. Res. (2000)
- Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1. Semenza, G.L., Agani, F., Iyer, N., Kotch, L., Laughner, E., Leung, S., Yu, A. Ann. N. Y. Acad. Sci. (1999)
- Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Semenza, G.L. Annu. Rev. Cell Dev. Biol. (1999)
