Giampaolo Tortora
Department of Endocrinology and Molecular and Clinical Oncology
University of Naples Federico II
Naples
Italy
Name/email consistency: high
- Combined targeting of EGFR-dependent and VEGF-dependent pathways: rationale, preclinical studies and clinical applications. Tortora, G., Ciardiello, F., Gasparini, G. Nature Clinical Practice. Oncology (2008)
- The rationale for the combination of selective EGFR inhibitors with cytotoxic drugs and radiotherapy. Tortora, G., Gelardi, T., Ciardiello, F., Bianco, R. Int. J. Biol. Markers (2007)
- Angiogenesis: a target for cancer therapy. Tortora, G., Melisi, D., Ciardiello, F. Curr. Pharm. Des. (2004)
- Combined targeted inhibition of bcl-2, bcl-XL, epidermal growth factor receptor, and protein kinase A type I causes potent antitumor, apoptotic, and antiangiogenic activity. Tortora, G., Caputo, R., Damiano, V., Caputo, R., Troiani, T., Veneziani, B.M., De Placido, S., Bianco, A.R., Zangemeister-Wittke, U., Ciardiello, F. Clin. Cancer Res. (2003)
- Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect. Tortora, G., Caputo, R., Damiano, V., Melisi, D., Bianco, R., Fontanini, G., Veneziani, B.M., De Placido, S., Bianco, A.R., Ciardiello, F. Clin. Cancer Res. (2003)
- Antisense targeting protein kinase A type I as a drug for integrated strategies of cancer therapy. Tortora, G., Ciardiello, F. Ann. N. Y. Acad. Sci. (2003)
- Preclinical and phase I study of oxaliplatin and topotecan in combination in human cancer. Tortora, G., Ciardiello, F., Damiano, V., De Laurentiis, M., Matano, E., Pepe, S., Pensabene, M., Catalano, G., De Placido, S., Bianco, A.R. Ann. Oncol. (2002)
- Protein kinase A as target for novel integrated strategies of cancer therapy. Tortora, G., Ciardiello, F. Ann. N. Y. Acad. Sci. (2002)
- Combined blockade of protein kinase A and bcl-2 by antisense strategy induces apoptosis and inhibits tumor growth and angiogenesis. Tortora, G., Caputo, R., Damiano, V., Bianco, R., Fontanini, G., Cuccato, S., De Placido, S., Bianco, A.R., Ciardiello, F. Clin. Cancer Res. (2001)
- Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity. Tortora, G., Caputo, R., Damiano, V., Fontanini, G., Melisi, D., Veneziani, B.M., Zunino, F., Bianco, A.R., Ciardiello, F. Clin. Cancer Res. (2001)
- Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production. Tortora, G., Bianco, R., Damiano, V., Fontanini, G., De Placido, S., Bianco, A.R., Ciardiello, F. Clin. Cancer Res. (2000)
- Targeting of epidermal growth factor receptor and protein kinase A: molecular basis and therapeutic applications. Tortora, G., Ciardiello, F. Ann. Oncol. (2000)
- A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer. Tortora, G., Caputo, R., Damiano, V., Bianco, R., Chen, J., Agrawal, S., Bianco, A.R., Ciardiello, F. Int. J. Cancer (2000)









