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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

F. Peter Guengerich

Department of Biochemistry

Vanderbilt University School of Medicine


Tennessee 37232-0146



Name/email consistency: high



  • Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA. 1996 - 2003
  • Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, 638 Medical Research Building I, 23rd Avenue South at Pierce, USA. 1999 - 2003
  • Osaka Prefectural Institute of Public Health, Osaka 537, Japan. 1996


  1. Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions. Guengerich, F.P. Arch. Biochem. Biophys. (2003) [Pubmed]
  2. Activation of dihaloalkanes by thiol-dependent mechanisms. Guengerich, F.P. J. Biochem. Mol. Biol. (2003) [Pubmed]
  3. Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies. Peter Guengerich, F., Chun, Y.J., Kim, D., Gillam, E.M., Shimada, T. Mutat. Res. (2003) [Pubmed]
  4. Update information on human P450s. Guengerich, F.P. Drug Metab. Rev. (2002) [Pubmed]
  5. Reaction of aflatoxin B(1) oxidation products with lysine. Guengerich, F.P., Arneson, K.O., Williams, K.M., Deng, Z., Harris, T.M. Chem. Res. Toxicol. (2002) [Pubmed]
  6. Structure of the aflatoxin B(1) dialdehyde adduct formed from reaction with methylamine. Guengerich, F.P., Voehler, M., Williams, K.M., Deng, Z., Harris, T.M. Chem. Res. Toxicol. (2002) [Pubmed]
  7. Cytochrome P450 enzymes in the generation of commercial products. Guengerich, F.P. Nat. Rev. Drug. Discov (2002) [Pubmed]
  8. N-hydroxyarylamines. Guengerich, F.P. Drug Metab. Rev. (2002) [Pubmed]
  9. Use of heterologously-expressed cytochrome P450 and glutathione transferase enzymes in toxicity assays. Guengerich, F.P., Wheeler, J.B., Chun, Y.J., Kim, D., Shimada, T., Aryal, P., Oda, Y., Gillam, E.M. Toxicology (2002) [Pubmed]
  10. Forging the links between metabolism and carcinogenesis. Guengerich, F.P. Mutat. Res. (2001) [Pubmed]
  11. Reduction of aflatoxin B1 dialdehyde by rat and human aldo-keto reductases. Guengerich, F.P., Cai, H., McMahon, M., Hayes, J.D., Sutter, T.R., Groopman, J.D., Deng, Z., Harris, T.M. Chem. Res. Toxicol. (2001) [Pubmed]
  12. Uncommon P450-catalyzed reactions. Guengerich, F.P. Curr. Drug Metab. (2001) [Pubmed]
  13. Metabolism of chemical carcinogens. Guengerich, F.P. Carcinogenesis (2000) [Pubmed]
  14. What makes P450s work? Searches for answers with known and new P450s. Guengerich, F.P., Parikh, A., Yun, C.H., Kim, D., Nakamura, K., Notley, L.M., Gillam, E.M. Drug Metab. Rev. (2000) [Pubmed]
  15. The Vanderbilt University Center in Molecular Toxicology: the first 30 years. Guengerich, F.P. Drug Metab. Rev. (1999) [Pubmed]
  16. Kinetics of hydrolysis and reaction of aflatoxin B1 exo-8,9-epoxide and relevance to toxicity and detoxication. Guengerich, F.P., Johnson, W.W. Drug Metab. Rev. (1999) [Pubmed]
  17. Cytochrome P-450 3A4: regulation and role in drug metabolism. Guengerich, F.P. Annu. Rev. Pharmacol. Toxicol. (1999) [Pubmed]
  18. Inter-individual differences in the metabolism of environmental toxicants: cytochrome P450 1A2 as a prototype. Guengerich, F.P., Parikh, A., Turesky, R.J., Josephy, P.D. Mutat. Res. (1999) [Pubmed]
  19. Formation and reactions of N(7)-aminoguanosine and derivatives. Guengerich, F.P., Mundkowski, R.G., Voehler, M., Kadlubar, F.F. Chem. Res. Toxicol. (1999) [Pubmed]
  20. Activation and detoxication of aflatoxin B1. Guengerich, F.P., Johnson, W.W., Shimada, T., Ueng, Y.F., Yamazaki, H., Langouët, S. Mutat. Res. (1998) [Pubmed]
  21. Activation of procarcinogens by human cytochrome P450 enzymes. Guengerich, F.P., Shimada, T. Mutat. Res. (1998) [Pubmed]
  22. Twenty years of biochemistry of human P450s: purification, expression, mechanism, and relevance to drugs. Guengerich, F.P., Hosea, N.A., Parikh, A., Bell-Parikh, L.C., Johnson, W.W., Gillam, E.M., Shimada, T. Drug Metab. Dispos. (1998) [Pubmed]
  23. Expression of drug-metabolizing enzymes. Guengerich, F.P., Parikh, A. Curr. Opin. Biotechnol. (1997) [Pubmed]
  24. Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems. Guengerich, F.P., Johnson, W.W. Biochemistry (1997) [Pubmed]
  25. Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species. Guengerich, F.P. Chem. Biol. Interact. (1997) [Pubmed]
  26. Involvement of cytochrome P450, glutathione S-transferase, and epoxide hydrolase in the metabolism of aflatoxin B1 and relevance to risk of human liver cancer. Guengerich, F.P., Johnson, W.W., Ueng, Y.F., Yamazaki, H., Shimada, T. Environ. Health Perspect. (1996) [Pubmed]
  27. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5. Yamazaki, H., Johnson, W.W., Ueng, Y.F., Shimada, T., Guengerich, F.P. J. Biol. Chem. (1996) [Pubmed]
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