David H. Gutmann
Washington University School of Medicine
Department of Neurology and Washington University Neurofibromatosis Center
660 South Euclid Avenue
St. Louis
USA
Name/email consistency: high
- Optimizing biologically targeted clinical trials for neurofibromatosis. Gutmann, D.H., Blakeley, J.O., Korf, B.R., Packer, R.J. Expert. Opin. Investig. Drugs (2013)
- Modeling human brain tumors in mice. Gutmann, D.H. Brain Pathol. (2009)
- Mouse Models of Human Cancers Consortium Workshop on Nervous System Tumors. Gutmann, D.H., Maher, E.A., Van Dyke, T. Cancer Res. (2006)
- Harnessing preclinical mouse models to inform human clinical cancer trials. Gutmann, D.H., Hunter-Schaedle, K., Shannon, K.M. J. Clin. Invest. (2006)
- Mouse models of human cancer consortium symposium on nervous system tumors. Gutmann, D.H., Baker, S.J., Giovannini, M., Garbow, J., Weiss, W. Cancer Res. (2003)
- Mlh1 deficiency accelerates myeloid leukemogenesis in neurofibromatosis 1 (Nf1) heterozygous mice. Gutmann, D.H., Winkeler, E., Kabbarah, O., Hedrick, N., Dudley, S., Goodfellow, P.J., Liskay, R.M. Oncogene (2003)
- Molecular analysis of astrocytomas presenting after age 10 in individuals with NF1. Gutmann, D.H., James, C.D., Poyhonen, M., Louis, D.N., Ferner, R., Guha, A., Hariharan, S., Viskochil, D., Perry, A. Neurology (2003)
- Mouse glioma gene expression profiling identifies novel human glioma-associated genes. Gutmann, D.H., Huang, Z.Y., Hedrick, N.M., Ding, H., Guha, A., Watson, M.A. Ann. Neurol. (2002)
- Comparative gene expression profile analysis of neurofibromatosis 1-associated and sporadic pilocytic astrocytomas. Gutmann, D.H., Hedrick, N.M., Li, J., Nagarajan, R., Perry, A., Watson, M.A. Cancer Res. (2002)
- Mouse models of neurofibromatosis 1 and 2. Gutmann, D.H., Giovannini, M. Neoplasia (2002)
- Gliomas presenting after age 10 in individuals with neurofibromatosis type 1 (NF1). Gutmann, D.H., Rasmussen, S.A., Wolkenstein, P., MacCollin, M.M., Guha, A., Inskip, P.D., North, K.N., Poyhonen, M., Birch, P.H., Friedman, J.M. Neurology (2002)
- Neurofibromin in the brain. Gutmann, D.H. J. Child Neurol. (2002)
- The neurofibromatoses: when less is more. Gutmann, D.H. Hum. Mol. Genet. (2001)
- The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the "open" conformation and suppresses cell growth and motility. Gutmann, D.H., Haipek, C.A., Burke, S.P., Sun, C.X., Scoles, D.R., Pulst, S.M. Hum. Mol. Genet. (2001)
- Functional analysis of neurofibromatosis 2 (NF2) missense mutations. Gutmann, D.H., Hirbe, A.C., Haipek, C.A. Hum. Mol. Genet. (2001)
- Heterozygosity for the neurofibromatosis 1 (NF1) tumor suppressor results in abnormalities in cell attachment, spreading and motility in astrocytes. Gutmann, D.H., Wu, Y.L., Hedrick, N.M., Zhu, Y., Guha, A., Parada, L.F. Hum. Mol. Genet. (2001)
- Expression of the tuberous sclerosis complex gene products, hamartin and tuberin, in central nervous system tissues. Gutmann, D.H., Zhang, Y., Hasbani, M.J., Goldberg, M.P., Plank, T.L., Petri Henske, E. Acta Neuropathol. (2000)
- Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas. Gutmann, D.H., Donahoe, J., Perry, A., Lemke, N., Gorse, K., Kittiniyom, K., Rempel, S.A., Gutierrez, J.A., Newsham, I.F. Hum. Mol. Genet. (2000)
- Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas. Gutmann, D.H., Donahoe, J., Brown, T., James, C.D., Perry, A. Neuropathol. Appl. Neurobiol. (2000)
- Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations. Gutmann, D.H., Haipek, C.A., Hoang Lu, K. J. Neurosci. Res. (1999)
- Increased expression of the NF2 tumor suppressor gene product, merlin, impairs cell motility, adhesionand spreading. Gutmann, D.H., Sherman, L., Seftor, L., Haipek, C., Hoang Lu, K., Hendrix, M. Hum. Mol. Genet. (1999)
- Defects in neurofibromatosis 2 protein function can arise at multiple levels. Gutmann, D.H., Geist, R.T., Xu, H., Kim, J.S., Saporito-Irwin, S. Hum. Mol. Genet. (1998)
- The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. Gutmann, D.H., Aylsworth, A., Carey, J.C., Korf, B., Marks, J., Pyeritz, R.E., Rubenstein, A., Viskochil, D. JAMA (1997)