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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Hans Diener

Department of Neurology and Headache Centre

University Duisburg-Essen




Name/email consistency: high



  • Department of Neurology and Headache Centre, University Duisburg-Essen, Essen, Germany. 1998 - 2011
  • University of Essen, Germany. 2006
  • Neurologische Universitätsklinik, Essen, Germany. 2005
  • Max-Planck Institute for Neurological Research and Department of Neurology, University of Cologne, Cologne, Germany. 2001


  1. Treatment of chronic migraine. Diener, H.C., Holle, D., Dodick, D. Curr. Pain. Headache. Rep (2011) [Pubmed]
  2. Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial. Diener, H.C., Connolly, S.J., Ezekowitz, M.D., Wallentin, L., Reilly, P.A., Yang, S., Xavier, D., Di Pasquale, G., Yusuf, S. Lancet. Neurol (2010) [Pubmed]
  3. Preventing stroke: the PRoFESS, ONTARGET, and TRANSCEND trial programs. Diener, H.C. J. Hypertens. Suppl (2009) [Pubmed]
  4. Telmisartan in migraine prophylaxis: a randomized, placebo-controlled trial. Diener, H.C., Gendolla, A., Feuersenger, A., Evers, S., Straube, A., Schumacher, H., Davidai, G. Cephalalgia (2009) [Pubmed]
  5. Utility of topiramate for the treatment of patients with chronic migraine in the presence or absence of acute medication overuse. Diener, H.C., Dodick, D.W., Goadsby, P.J., Bigal, M.E., Bussone, G., Silberstein, S.D., Mathew, N., Ascher, S., Morein, J., Hulihan, J.F., Biondi, D.M., Greenberg, S.J. Cephalalgia (2009) [Pubmed]
  6. Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study. Diener, H.C., Sacco, R.L., Yusuf, S., Cotton, D., Ounpuu, S., Lawton, W.A., Palesch, Y., Martin, R.H., Albers, G.W., Bath, P., Bornstein, N., Chan, B.P., Chen, S.T., Cunha, L., Dahlöf, B., De Keyser, J., Donnan, G.A., Estol, C., Gorelick, P., Gu, V., Hermansson, K., Hilbrich, L., Kaste, M., Lu, C., Machnig, T., Pais, P., Roberts, R., Skvortsova, V., Teal, P., Toni, D., VanderMaelen, C., Voigt, T., Weber, M., Yoon, B.W. Lancet. Neurol (2008) [Pubmed]
  7. Identification of negative predictors of pain-free response to triptans: analysis of the eletriptan database. Diener, H.C., Dodick, D.W., Goadsby, P.J., Lipton, R.B., Almas, M., Parsons, B. Cephalalgia (2008) [Pubmed]
  8. Headache associated with ischemic cerebrovascular disease. Diener, H.C., Katsarava, Z., Weimar, C. Rev. Neurol. (Paris) (2008) [Pubmed]
  9. Systemic risk score evaluation in ischemic stroke patients (SCALA): a prospective cross sectional study in 85 German stroke units. Weimar, C., Goertler, M., Röther, J., Ringelstein, E.B., Darius, H., Nabavi, D.G., Kim, I.H., Theobald, K., Diener, H.C. J. Neurol. (2007) [Pubmed]
  10. The PRoFESS trial: future impact on secondary stroke prevention. Diener, H.C. Expert. Rev. Neurother (2007) [Pubmed]
  11. Rationale, design and baseline data of a randomized, double-blind, controlled trial comparing two antithrombotic regimens (a fixed-dose combination of extended-release dipyridamole plus ASA with clopidogrel) and telmisartan versus placebo in patients with strokes: the Prevention Regimen for Effectively Avoiding Second Strokes Trial (PRoFESS). Diener, H.C., Sacco, R., Yusuf, S. Cerebrovasc. Dis. (2007) [Pubmed]
  12. Patent foramen ovale and migraine: no reason to intervene. Diener, H.C. J. Headache. Pain (2007) [Pubmed]
  13. Lower cervical disc prolapse may cause cervicogenic headache: prospective study in patients undergoing surgery. Diener, H.C., Kaminski, M., Stappert, G., Stolke, D., Schoch, B. Cephalalgia (2007) [Pubmed]
  14. Secondary stroke prevention with antiplatelet drugs: have we reached the ceiling? Diener, H.C. Int. J. Stroke (2006) [Pubmed]
  15. Prophylaxis of thrombotic and embolic events in acute ischemic stroke with the low-molecular-weight heparin certoparin: results of the PROTECT Trial. Diener, H.C., Ringelstein, E.B., von Kummer, R., Landgraf, H., Koppenhagen, K., Harenberg, J., Rektor, I., Csányi, A., Schneider, D., Klingelhöfer, J., Brom, J., Weidinger, G. Stroke (2006) [Pubmed]
  16. Stroke prevention using the oral direct thrombin inhibitor ximelagatran in patients with non-valvular atrial fibrillation. Pooled analysis from the SPORTIF III and V studies. Diener, H.C. Cerebrovasc. Dis. (2006) [Pubmed]
  17. Efficacy of acupuncture for the prophylaxis of migraine: a multicentre randomised controlled clinical trial. Diener, H.C., Kronfeld, K., Boewing, G., Lungenhausen, M., Maier, C., Molsberger, A., Tegenthoff, M., Trampisch, H.J., Zenz, M., Meinert, R. Lancet. Neurol (2006) [Pubmed]
  18. Patent foramen ovale, migraine and stroke: no reason to intervene. Diener, H.C., Weimar, C. Nature Clinical Practice. Cardiovascular Medicine (2006) [Pubmed]
  19. Primary and secondary stroke prevention with antiplatelet drugs. Diener, H.C. Curr. Pharm. Des. (2006) [Pubmed]
  20. Aspirin in the treatment of acute migraine attacks. Diener, H.C., Lampl, C., Reimnitz, P., Voelker, M. Expert. Rev. Neurother (2006) [Pubmed]
  21. Efficacy and tolerability of diclofenac potassium sachets in migraine: a randomized, double-blind, cross-over study in comparison with diclofenac potassium tablets and placebo. Diener, H.C., Montagna, P., Gács, G., Lyczak, P., Schumann, G., Zöller, B., Mulder, L.J., Siegel, J., Edson, K. Cephalalgia (2006) [Pubmed]
  22. How much esprit is in ESPRIT?. Diener, H.C. Stroke (2006) [Pubmed]
  23. Eletriptan in migraine. Diener, H.C. Expert. Rev. Neurother (2005) [Pubmed]
  24. Patent foramen ovale: paradoxical connection to migraine and stroke. Diener, H.C., Weimar, C., Katsarava, Z. Curr. Opin. Neurol. (2005) [Pubmed]
  25. Almotriptan in migraine patients who respond poorly to oral sumatriptan: a double-blind, randomized trial. Diener, H.C., Gendolla, A., Gebert, I., Beneke, M. Eur. Neurol. (2005) [Pubmed]
  26. Is clopidogrel the antiplatelet drug of choice for high-risk patients with stroke/TIA?: Yes. Diener, H.C. J. Thromb. Haemost. (2005) [Pubmed]
  27. Part IV: effects of zolmitriptan orally disintegrating tablet on migraine symptoms and ability to perform normal activities: a post-marketing surveillance study in Germany. Diener, H.C., Gendolla, A. Curr. Med. Res. Opin (2005) [Pubmed]
  28. Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention--a randomized, double-blind, multicentre, placebo-controlled study. Diener, H.C., Pfaffenrath, V., Schnitker, J., Friede, M., Henneicke-von Zepelin, H.H. Cephalalgia (2005) [Pubmed]
  29. Efficacy of almotriptan 12.5 mg in achieving migraine-related composite endpoints: a double-blind, randomized, placebo-controlled study in patients controlled study in patients with previous poor response to sumatriptan 50 mg. Diener, H.C. Curr. Med. Res. Opin (2005) [Pubmed]
  30. Important advances in headache. Diener, H.C. Lancet. Neurol (2004) [Pubmed]
  31. The 40-mg dose of eletriptan: comparative efficacy and tolerability versus sumatriptan 100 mg. Diener, H.C., Ryan, R., Sun, W., Hettiarachchi, J. Eur. J. Neurol. (2004) [Pubmed]
  32. The first placebo-controlled trial of a special butterbur root extract for the prevention of migraine: reanalysis of efficacy criteria. Diener, H.C., Rahlfs, V.W., Danesch, U. Eur. Neurol. (2004) [Pubmed]
  33. Management of atherothrombosis with clopidogrel in high-risk patients with recent transient ischaemic attack or ischaemic stroke (MATCH): study design and baseline data. Diener, H.C., Bogousslavsky, J., Brass, L.M., Cimminiello, C., Csiba, L., Kaste, M., Leys, D., Matias-Guiu, J., Rupprecht, H.J. Cerebrovasc. Dis. (2004) [Pubmed]
  34. Efficacy of 1,000 mg effervescent acetylsalicylic acid and sumatriptan in treating associated migraine symptoms. Diener, H.C., Eikermann, A., Gessner, U., Göbel, H., Haag, G., Lange, R., May, A., Müller-Schwefe, G., Voelker, M. Eur. Neurol. (2004) [Pubmed]
  35. Medication-overuse headache: a worldwide problem. Diener, H.C., Limmroth, V. Lancet. Neurol (2004) [Pubmed]
  36. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Diener, H.C., Bogousslavsky, J., Brass, L.M., Cimminiello, C., Csiba, L., Kaste, M., Leys, D., Matias-Guiu, J., Rupprecht, H.J. Lancet (2004) [Pubmed]
  37. Predicting the response to sumatriptan: the Sumatriptan Naratriptan Aggregate Patient Database. Christoph-Diener, H., Ferrari, M., Mansbach, H. Neurology (2004) [Pubmed]
  38. Topiramate in migraine prophylaxis--results from a placebo-controlled trial with propranolol as an active control. Diener, H.C., Tfelt-Hansen, P., Dahlöf, C., Láinez, M.J., Sandrini, G., Wang, S.J., Neto, W., Vijapurkar, U., Doyle, A., Jacobs, D. J. Neurol. (2004) [Pubmed]
  39. Placebo-controlled comparison of effervescent acetylsalicylic acid, sumatriptan and ibuprofen in the treatment of migraine attacks. Diener, H.C., Bussone, G., de Liano, H., Eikermann, A., Englert, R., Floeter, T., Gallai, V., Göbel, H., Hartung, E., Jimenez, M.D., Lange, R., Manzoni, G.C., Mueller-Schwefe, G., Nappi, G., Pinessi, L., Prat, J., Puca, F.M., Titus, F., Voelker, M. Cephalalgia (2004) [Pubmed]
  40. RPR100893, a substance-P antagonist, is not effective in the treatment of migraine attacks. Diener, H.C. Cephalalgia (2003) [Pubmed]
  41. Pharmacological approaches to migraine. Diener, H. J. Neural Transm. Suppl. (2003) [Pubmed]
  42. Efficacy, tolerability and safety of oral eletriptan and ergotamine plus caffeine (Cafergot) in the acute treatment of migraine: a multicentre, randomised, double-blind, placebo-controlled comparison. Diener, H.C., Jansen, J.P., Reches, A., Pascual, J., Pitei, D., Steiner, T.J. Eur. Neurol. (2002) [Pubmed]
  43. Treatment of acute ischaemic stroke with the low-affinity, use-dependent NMDA antagonist AR-R15896AR. A safety and tolerability study. Diener, H.C., AlKhedr, A., Busse, O., Hacke, W., Zingmark, P.H., Jonsson, N., Basun, H. J. Neurol. (2002) [Pubmed]
  44. Efficacy and tolerability in migraine prophylaxis of flunarizine in reduced doses: a comparison with propranolol 160 mg daily. Diener, H.C., Matias-Guiu, J., Hartung, E., Pfaffenrath, V., Ludin, H.P., Nappi, G., De Beukelaar, F. Cephalalgia (2002) [Pubmed]
  45. Aspirin therapy should be first-line treatment in secondary prevention of stroke--against. Diener, H.C. Stroke (2002) [Pubmed]
  46. Nitrous oxide modulator: lubeluzole. Diener, H.C., Wessel, T.C. Curr. Med. Res. Opin (2002) [Pubmed]
  47. Treatment of acute ischemic stroke with the low-molecular-weight heparin certoparin: results of the TOPAS trial. Therapy of Patients With Acute Stroke (TOPAS) Investigators. Diener, H.C., Ringelstein, E.B., von Kummer, R., Langohr, H.D., Bewermeyer, H., Landgraf, H., Hennerici, M., Welzel, D., Gräve, M., Brom, J., Weidinger, G. Stroke (2001) [Pubmed]
  48. Imaging in cerebrovascular disease. Heiss, W.D., Forsting, M., Diener, H.C. Curr. Opin. Neurol. (2001) [Pubmed]
  49. Cyclandelate in the prophylaxis of migraine: a placebo-controlled study. Diener, H.C., Krupp, P., Schmitt, T., Steitz, G., Milde, K., Freytag, S. Cephalalgia (2001) [Pubmed]
  50. A comparative study of oral acetylsalicyclic acid and metoprolol for the prophylactic treatment of migraine. A randomized, controlled, double-blind, parallel group phase III study. Diener, H.C., Hartung, E., Chrubasik, J., Evers, S., Schoenen, J., Eikermann, A., Latta, G., Hauke, W. Cephalalgia (2001) [Pubmed]
  51. Treatment of migraine attacks with intranasal alniditan: an open study. Diener, H.C., Louis, P., Schellens, R., De Beukelaar, F. Cephalalgia (2001) [Pubmed]
  52. A preliminary, randomized, multicenter study comparing intravenous immunoglobulin, plasma exchange, and immune adsorption in Guillain-Barré syndrome. Diener, H.C., Haupt, W.F., Kloss, T.M., Rosenow, F., Philipp, T., Koeppen, S., Vietorisz, A. Eur. Neurol. (2001) [Pubmed]
  53. The efficacy and safety of sc alniditan vs. sc sumatriptan in the acute treatment of migraine: a randomized, double-blind, placebo-controlled trial. Diener, H.C., Tfelt-Hansen, P., de Beukelaar, F., Ferrari, M.D., Olesen, J., Dahlöf, C., Mathew, N. Cephalalgia (2001) [Pubmed]
  54. Analgesic/abortive overuse and misuse in chronic daily headache. Diener, H.C., Katasarva, Z. Curr. Pain. Headache. Rep (2001) [Pubmed]
  55. Advances in pharmacological treatment of migraine. Diener, H.C., Limmroth, V. Expert. Opin. Investig. Drugs (2001) [Pubmed]
  56. Analgesics. Diener, H.C., Limmroth, V. Curr. Med. Res. Opin (2001) [Pubmed]
  57. Medication overuse headache. Diener, H.C., Katsarava, Z. Curr. Med. Res. Opin (2001) [Pubmed]
  58. Stroke prevention: anti-platelet and anti-thrombolytic therapy. Diener, H.C. Neurol. Clin (2000) [Pubmed]
  59. Lubeluzole in acute ischemic stroke treatment: A double-blind study with an 8-hour inclusion window comparing a 10-mg daily dose of lubeluzole with placebo. Diener, H.C., Cortens, M., Ford, G., Grotta, J., Hacke, W., Kaste, M., Koudstaal, P.J., Wessel, T. Stroke (2000) [Pubmed]
  60. Stroke prevention: antiplatelet and antithrombolytic therapy. Diener, H.C. Haemostasis (2000) [Pubmed]
  61. Efficacy and safety of intravenous acetylsalicylic acid lysinate compared to subcutaneous sumatriptan and parenteral placebo in the acute treatment of migraine. A double-blind, double-dummy, randomized, multicenter, parallel group study. The ASASUMAMIG Study Group. Diener, H.C. Cephalalgia (1999) [Pubmed]
  62. Antimigraine drugs. Diener, H.C., Kaube, H., Limmroth, V. J. Neurol. (1999) [Pubmed]
  63. Acute management of migraine: triptans and beyond. Diener, H.C., Limmroth, V. Curr. Opin. Neurol. (1999) [Pubmed]
  64. Unbalanced randomization influences placebo response: scientific versus ethical issues around the use of placebo in migraine trials. Diener, H.C., Dowson, A.J., Ferrari, M., Nappi, G., Tfelt-Hansen, P. Cephalalgia (1999) [Pubmed]
  65. A practical guide to the management and prevention of migraine. Diener, H.C., Kaube, H., Limmroth, V. Drugs (1998) [Pubmed]
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