Stephen Hiscox
Welsh School of Pharmacy
Cardiff University
Wales
UK
Name/email consistency: high
- Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. Hiscox, S., Baruha, B., Smith, C., Bellerby, R., Goddard, L., Jordan, N., Poghosyan, Z., Nicholson, R.I., Barrett-Lee, P., Gee, J. BMC. Cancer (2012)
- Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells. Hiscox, S., Barnfather, P., Hayes, E., Bramble, P., Christensen, J., Nicholson, R.I., Barrett-Lee, P. Breast Cancer Res. Treat. (2011)
- Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells. Hiscox, S., Jordan, N.J., Smith, C., James, M., Morgan, L., Taylor, K.M., Green, T.P., Nicholson, R.I. Breast Cancer Res. Treat. (2009)
- Aromatase inhibitors in breast cancer. Hiscox, S., Davies, E.L., Barrett-Lee, P. Maturitas (2009)
- Src inhibitors in breast cancer therapy. Hiscox, S., Nicholson, R.I. Expert Opin. Ther. Targets (2008)
- Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells. Hiscox, S., Jordan, N.J., Morgan, L., Green, T.P., Nicholson, R.I. Clin. Exp. Metastasis (2007)
- Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation. Hiscox, S., Jiang, W.G., Obermeier, K., Taylor, K., Morgan, L., Burmi, R., Barrow, D., Nicholson, R.I. Int. J. Cancer (2006)
- Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Hiscox, S., Morgan, L., Green, T.P., Barrow, D., Gee, J., Nicholson, R.I. Breast Cancer Res. Treat. (2006)
- Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: implications for tumour-stroma interactions. Hiscox, S., Jordan, N.J., Jiang, W., Harper, M., McClelland, R., Smith, C., Nicholson, R.I. Endocr. Relat. Cancer (2006)
- Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer. Hiscox, S., Morgan, L., Green, T., Nicholson, R.I. Endocr. Relat. Cancer (2006)
- Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839). Hiscox, S., Morgan, L., Barrow, D., Dutkowskil, C., Wakeling, A., Nicholson, R.I. Clin. Exp. Metastasis (2004)