Helmy M. Siragy
PO Box 801409
University of Virginia Health System
Charlottesville
VA 22908-1409
Name/email consistency: medium
- Sodium Depletion Enhances Renal Expression of (Pro)Renin Receptor via Cyclic GMP-Protein Kinase G Signaling Pathway. Huang, J., Siragy, H.M. Hypertension (2012)
- Rationale for combining a direct renin inhibitor with other renin- angiotensin system blockers. Focus on aliskiren and combinations. Siragy, H.M. Cardiovasc. Drugs. Ther (2011)
- Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension. Matavelli, L.C., Huang, J., Siragy, H.M. Hypertension (2011)
- Role of the intrarenal renin-angiotensin-aldosterone system in chronic kidney disease. Siragy, H.M., Carey, R.M. Am. J. Nephrol. (2010)
- The angiotensin II type 2 receptor and the kidney. Siragy, H.M. J. Renin. Angiotensin. Aldosterone. Syst (2010)
- Comparing angiotensin II receptor blockers on benefits beyond blood pressure. Siragy, H.M. Adv. Ther (2010)
- Improving vascular function in hypertension: potential benefits of combination therapy with amlodipine and renin-angiotensin-aldosterone system blockers. Siragy, H.M. J. Hypertens. (2010)
- The potential role of the angiotensin subtype 2 receptor in cardiovascular protection. Siragy, H.M. Curr. Hypertens. Rep. (2009)
- ACCOMPLISH the goal: hypertension and beyond. Siragy, H.M. Curr. Hypertens. Rep. (2009)
- Evidence for benefits of angiotensin receptor blockade beyond blood pressure control. Siragy, H.M. Curr. Hypertens. Rep. (2008)
- The development of the direct renin inhibitor aliskiren: treating hypertension and beyond. Siragy, H., Huang, J., Lieb, D.C. Expert. Opin. Emerg. Drugs (2008)
- Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats. Siragy, H.M., Xue, C. Exp. Physiol. (2008)
- Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity. Siragy, H.M., Huang, J. Exp. Physiol. (2008)
- NO and cGMP mediate angiotensin AT2 receptor-induced renal renin inhibition in young rats. Siragy, H.M., Inagami, T., Carey, R.M. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2007)
- Renin inhibition: a new modality for hypertension management. Siragy, H.M. Curr. Hypertens. Rep. (2007)
- TROPHY for preventing hypertension. Siragy, H.M. Curr. Hypertens. Rep. (2007)
- Angiotensin AT1 and AT2 receptors--the battle for health and disease. Siragy, H.M. Nephrol. Dial. Transplant. (2007)
- Angiotensin II compartmentalization within the kidney: effects of salt diet and blood pressure alterations. Siragy, H.M. Curr. Opin. Nephrol. Hypertens. (2006)
- Beneficial effects of combined benazepril-amlodipine on cardiac nitric oxide, cGMP, and TNF-alpha production after cardiac ischemia. Siragy, H.M., Xue, C., Webb, R.L. J. Cardiovasc. Pharmacol. (2006)
- Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Siragy, H.M., Xue, C., Abadir, P., Carey, R.M. Hypertension (2005)
- Clinical trials report. Beta-blockade in diabetes: alleviating the concerns. Siragy, H.M. Curr. Hypertens. Rep. (2005)
- AT1 and AT2 receptor in the kidney: role in health and disease. Siragy, H.M. Semin. Nephrol. (2004)
- The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-alpha in diabetic rats. Siragy, H.M., Awad, A., Abadir, P., Webb, R. Endocrinology (2003)
- Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitors or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Siragy, H.M. Curr. Hypertens. Rep. (2003)
- Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP. Siragy, H.M., El-Kersh, M.A., De Gasparo, M., Webb, R.L., Carey, R.M. J. Hypertens. (2002)
- Angiotensin receptor blockers: how important is selectivity?. Siragy, H.M. Am. J. Hypertens. (2002)
- Angiotensin type 2 receptors: potential importance in the regulation of blood pressure. Siragy, H.M., Carey, R.M. Curr. Opin. Nephrol. Hypertens. (2001)
- Angiotensin-converting enzyme inhibition potentiates angiotensin II type 1 receptor effects on renal bradykinin and cGMP. Siragy, H.M., de Gasparo, M., El-Kersh, M., Carey, R.M. Hypertension (2001)
- Angiotensin type 2 receptor mediates valsartan-induced hypotension in conscious rats. Siragy, H.M., de Gasparo, M., Carey, R.M. Hypertension (2000)
- Prospective trials of angiotensin receptor blockers: beyond blood pressure control. Siragy, H.M., Carey, R.M. Curr. Hypertens. Rep. (2000)
- AT(1) and AT(2) receptors in the kidney: role in disease and treatment. Siragy, H.M. Am. J. Kidney Dis. (2000)
- Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model. Siragy, H.M., Carey, R.M. Hypertension (1999)
- The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats. Siragy, H.M., Carey, R.M. J. Clin. Invest. (1997)









