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Helmy M. Siragy

PO Box 801409

University of Virginia Health System

Charlottesville

VA 22908-1409

[email]@virginia.edu

Name/email consistency: medium

 
 
 
 
 
 
 

Affiliations

  • PO Box 801409, University of Virginia Health System, Charlottesville, VA 22908-1409. 2012
  • Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville, USA. 1997 - 2011

References

  1. Sodium Depletion Enhances Renal Expression of (Pro)Renin Receptor via Cyclic GMP-Protein Kinase G Signaling Pathway. Huang, J., Siragy, H.M. Hypertension (2012) [Pubmed]
  2. Rationale for combining a direct renin inhibitor with other renin- angiotensin system blockers. Focus on aliskiren and combinations. Siragy, H.M. Cardiovasc. Drugs. Ther (2011) [Pubmed]
  3. Angiotensin AT₂ receptor stimulation inhibits early renal inflammation in renovascular hypertension. Matavelli, L.C., Huang, J., Siragy, H.M. Hypertension (2011) [Pubmed]
  4. Role of the intrarenal renin-angiotensin-aldosterone system in chronic kidney disease. Siragy, H.M., Carey, R.M. Am. J. Nephrol. (2010) [Pubmed]
  5. The angiotensin II type 2 receptor and the kidney. Siragy, H.M. J. Renin. Angiotensin. Aldosterone. Syst (2010) [Pubmed]
  6. Comparing angiotensin II receptor blockers on benefits beyond blood pressure. Siragy, H.M. Adv. Ther (2010) [Pubmed]
  7. Improving vascular function in hypertension: potential benefits of combination therapy with amlodipine and renin-angiotensin-aldosterone system blockers. Siragy, H.M. J. Hypertens. (2010) [Pubmed]
  8. The potential role of the angiotensin subtype 2 receptor in cardiovascular protection. Siragy, H.M. Curr. Hypertens. Rep. (2009) [Pubmed]
  9. ACCOMPLISH the goal: hypertension and beyond. Siragy, H.M. Curr. Hypertens. Rep. (2009) [Pubmed]
  10. Evidence for benefits of angiotensin receptor blockade beyond blood pressure control. Siragy, H.M. Curr. Hypertens. Rep. (2008) [Pubmed]
  11. The development of the direct renin inhibitor aliskiren: treating hypertension and beyond. Siragy, H., Huang, J., Lieb, D.C. Expert. Opin. Emerg. Drugs (2008) [Pubmed]
  12. Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats. Siragy, H.M., Xue, C. Exp. Physiol. (2008) [Pubmed]
  13. Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity. Siragy, H.M., Huang, J. Exp. Physiol. (2008) [Pubmed]
  14. NO and cGMP mediate angiotensin AT2 receptor-induced renal renin inhibition in young rats. Siragy, H.M., Inagami, T., Carey, R.M. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2007) [Pubmed]
  15. Renin inhibition: a new modality for hypertension management. Siragy, H.M. Curr. Hypertens. Rep. (2007) [Pubmed]
  16. TROPHY for preventing hypertension. Siragy, H.M. Curr. Hypertens. Rep. (2007) [Pubmed]
  17. Angiotensin AT1 and AT2 receptors--the battle for health and disease. Siragy, H.M. Nephrol. Dial. Transplant. (2007) [Pubmed]
  18. Angiotensin II compartmentalization within the kidney: effects of salt diet and blood pressure alterations. Siragy, H.M. Curr. Opin. Nephrol. Hypertens. (2006) [Pubmed]
  19. Beneficial effects of combined benazepril-amlodipine on cardiac nitric oxide, cGMP, and TNF-alpha production after cardiac ischemia. Siragy, H.M., Xue, C., Webb, R.L. J. Cardiovasc. Pharmacol. (2006) [Pubmed]
  20. Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Siragy, H.M., Xue, C., Abadir, P., Carey, R.M. Hypertension (2005) [Pubmed]
  21. Clinical trials report. Beta-blockade in diabetes: alleviating the concerns. Siragy, H.M. Curr. Hypertens. Rep. (2005) [Pubmed]
  22. AT1 and AT2 receptor in the kidney: role in health and disease. Siragy, H.M. Semin. Nephrol. (2004) [Pubmed]
  23. The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-alpha in diabetic rats. Siragy, H.M., Awad, A., Abadir, P., Webb, R. Endocrinology (2003) [Pubmed]
  24. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitors or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Siragy, H.M. Curr. Hypertens. Rep. (2003) [Pubmed]
  25. Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP. Siragy, H.M., El-Kersh, M.A., De Gasparo, M., Webb, R.L., Carey, R.M. J. Hypertens. (2002) [Pubmed]
  26. Angiotensin receptor blockers: how important is selectivity?. Siragy, H.M. Am. J. Hypertens. (2002) [Pubmed]
  27. Angiotensin type 2 receptors: potential importance in the regulation of blood pressure. Siragy, H.M., Carey, R.M. Curr. Opin. Nephrol. Hypertens. (2001) [Pubmed]
  28. Angiotensin-converting enzyme inhibition potentiates angiotensin II type 1 receptor effects on renal bradykinin and cGMP. Siragy, H.M., de Gasparo, M., El-Kersh, M., Carey, R.M. Hypertension (2001) [Pubmed]
  29. Angiotensin type 2 receptor mediates valsartan-induced hypotension in conscious rats. Siragy, H.M., de Gasparo, M., Carey, R.M. Hypertension (2000) [Pubmed]
  30. Prospective trials of angiotensin receptor blockers: beyond blood pressure control. Siragy, H.M., Carey, R.M. Curr. Hypertens. Rep. (2000) [Pubmed]
  31. AT(1) and AT(2) receptors in the kidney: role in disease and treatment. Siragy, H.M. Am. J. Kidney Dis. (2000) [Pubmed]
  32. Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model. Siragy, H.M., Carey, R.M. Hypertension (1999) [Pubmed]
  33. The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats. Siragy, H.M., Carey, R.M. J. Clin. Invest. (1997) [Pubmed]
 
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