Hong Chang
Department of Laboratory Hematology
University Health Network
University of Toronto
Toronto
Canada
Name/email consistency: high
- Impact of cytogenetics in patients with relapsed or refractory multiple myeloma treated with bortezomib: Adverse effect of 1q21 gains. Chang, H., Trieu, Y., Qi, X., Jiang, N.N., Xu, W., Reece, D. Leuk. Res. (2011)
- Impact of genomic aberrations including chromosome 1 abnormalities on the outcome of patients with relapsed or refractory multiple myeloma treated with lenalidomide and dexamethasone. Chang, H., Jiang, A., Qi, C., Trieu, Y., Chen, C., Reece, D. Leuk. Lymphoma (2010)
- CKS1B nuclear expression is inversely correlated with p27Kip1 expression and is predictive of an adverse survival in patients with multiple myeloma. Chang, H., Jiang, N., Jiang, H., Saha, M.N., Qi, C., Xu, W., Reece, D. Haematologica (2010)
- 1p21 deletions are strongly associated with 1q21 gains and are an independent adverse prognostic factor for the outcome of high-dose chemotherapy in patients with multiple myeloma. Chang, H., Qi, X., Jiang, A., Xu, W., Young, T., Reece, D. Bone Marrow Transplant. (2010)
- Genetic aberrations including chromosome 1 abnormalities and clinical features of plasma cell leukemia. Chang, H., Qi, X., Yeung, J., Reece, D., Xu, W., Patterson, B. Leuk. Res. (2009)
- Prognostic relevance of 6q deletion in Waldenström's macroglobulinemia: a multicenter study. Chang, H., Qi, C., Trieu, Y., Jiang, A., Young, K.H., Chesney, A., Jani, P., Wang, C., Reece, D., Chen, C. Clin. Lymphoma. Myeloma (2009)
- CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype. Chang, H., Yeung, J., Brandwein, J., Yi, Q.L. Leuk. Res. (2007)
- Bortezomib therapy response is independent of cytogenetic abnormalities in relapsed/refractory multiple myeloma. Chang, H., Trieu, Y., Qi, X., Xu, W., Stewart, K.A., Reece, D. Leuk. Res. (2007)
- Aberrant nuclear p53 protein expression detected by immunohistochemistry is associated with hemizygous P53 deletion and poor survival for multiple myeloma. Chang, H., Yeung, J., Qi, C., Xu, W. Br. J. Haematol. (2007)
- Chromosome 1p21 deletion is a novel prognostic marker in patients with multiple myeloma. Chang, H., Ning, Y., Qi, X., Yeung, J., Xu, W. Br. J. Haematol. (2007)
- Analysis of 6q deletion in Waldenstrom macroglobulinemia. Chang, H., Qi, X., Xu, W., Reader, J.C., Ning, Y. Eur. J. Haematol. (2007)
- Analysis of PTEN deletions and mutations in multiple myeloma. Chang, H., Qi, X.Y., Claudio, J., Zhuang, L., Patterson, B., Stewart, A.K. Leuk. Res. (2006)
- Prognostic relevance of CD56 expression in multiple myeloma: a study including 107 cases treated with high-dose melphalan-based chemotherapy and autologous stem cell transplant. Chang, H., Samiee, S., Yi, Q.L. Leuk. Lymphoma (2006)
- Significant increase of CKS1B amplification from monoclonal gammopathy of undetermined significance to multiple myeloma and plasma cell leukaemia as demonstrated by interphase fluorescence in situ hybridisation. Chang, H., Yeung, J., Xu, W., Ning, Y., Patterson, B. Br. J. Haematol. (2006)
- Multiple myeloma patients with CKS1B gene amplification have a shorter progression-free survival post-autologous stem cell transplantation. Chang, H., Qi, X., Trieu, Y., Xu, W., Reader, J.C., Ning, Y., Reece, D. Br. J. Haematol. (2006)
- p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation. Chang, H., Qi, C., Yi, Q.L., Reece, D., Stewart, A.K. Blood (2005)
- Genomic aberrations in plasma cell leukemia shown by interphase fluorescence in situ hybridization. Chang, H., Sloan, S., Li, D., Patterson, B. Cancer Genet. Cytogenet. (2005)
- Clonality analysis of cell lineages in acute myeloid leukemia with inversion 16. Chang, H., Nayar, R., Li, D., Sutherland, D.R. Cancer Genet. Cytogenet. (2005)
- Immunohistochemistry accurately predicts FGFR3 aberrant expression and t(4;14) in multiple myeloma. Chang, H., Stewart, A.K., Qi, X.Y., Li, Z.H., Yi, Q.L., Trudel, S. Blood (2005)
- Identification of cell lineages involved by t(15;17) in acute promyelocytic leukemia by combined fluorescence activated cell sorting and FISH. Chang, H., Qi, X.Y., Sutherland, D.R. Cancer Genet. Cytogenet. (2005)
- The absence of CD56 on malignant plasma cells in the cerebrospinal fluid is the hallmark of multiple myeloma involving central nervous system. Chang, H., Bartlett, E.S., Patterson, B., Chen, C.I., Yi, Q.L. Br. J. Haematol. (2005)
- Genetic risk identifies multiple myeloma patients who do not benefit from autologous stem cell transplantation. Chang, H., Qi, X.Y., Samiee, S., Yi, Q.L., Chen, C., Trudel, S., Mikhael, J., Reece, D., Stewart, A.K. Bone Marrow Transplant. (2005)
- Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia. Chang, H., Salma, F., Yi, Q.L., Patterson, B., Brien, B., Minden, M.D. Leuk. Res. (2004)
- Molecular cytogenetic abnormalities in patients with concurrent chronic lymphocytic leukemia and multiple myeloma shown by interphase fluorescence in situ hybridization: evidence of distinct clonal origin. Chang, H., Wechalekar, A., Li, L., Reece, D. Cancer Genet. Cytogenet. (2004)
- Interphase cytogenetic analysis of clonality in peripheral blood cells from a patient with Down syndrome and acute megakaryoblastic leukemia. Chang, H., Li, D., Nayar, R., Ye, C., Lau, W., Sutherland, D.R. Cancer Genet. Cytogenet. (2004)
- The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant. Chang, H., Sloan, S., Li, D., Zhuang, L., Yi, Q.L., Chen, C.I., Reece, D., Chun, K., Keith Stewart, A. Br. J. Haematol. (2004)
- Chronic lymphocytic leukemia in the course of chronic myelocytic leukemia: evidence of independent clonal origin as shown by interphase fluorescence in situ hybridization and fluorescence-activated cell sorting. Chang, H., Sutherland, R., Nayar, R., Li, D., Kamel-Reid, S., Mile, M.A., Messner, H., Lipton, J. Cancer Genet. Cytogenet. (2004)
- Extramedullary infiltrates of AML are associated with CD56 expression, 11q23 abnormalities and inferior clinical outcome. Chang, H., Brandwein, J., Yi, Q.L., Chun, K., Patterson, B., Brien, B. Leuk. Res. (2004)
- Detection of chromosome 13q deletions and IgH translocations in patients with multiple myeloma by FISH: comparison with karyotype analysis. Chang, H., Li, D., Zhuang, L., Nie, E., Bouman, D., Stewart, A.K., Chun, K. Leuk. Lymphoma (2004)
- Multiple myeloma involving central nervous system: high frequency of chromosome 17p13.1 (p53) deletions. Chang, H., Sloan, S., Li, D., Keith Stewart, A. Br. J. Haematol. (2004)
