Ian A. York
Department of Pathology
University of Massachusetts Medical School
55 Lake Avenue North
Worcester
USA
Name/email consistency: high
- Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. York, I.A., Brehm, M.A., Zendzian, S., Towne, C.F., Rock, K.L. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation. York, I.A., Bhutani, N., Zendzian, S., Goldberg, A.L., Rock, K.L. J. Immunol. (2006)
- A mutant cell with a novel defect in MHC class I quality control. York, I.A., Grant, E.P., Dahl, A.M., Rock, K.L. J. Immunol. (2005)
- The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. York, I.A., Chang, S.C., Saric, T., Keys, J.A., Favreau, J.M., Goldberg, A.L., Rock, K.L. Nat. Immunol. (2002)
