James C. Barrow
Department of Medicinal Chemistry
Merck Research Laboratories
West Point
Pennsylvania 19486
USA
Name/email consistency: high
- Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase. Barrow, J.C., Stauffer, S.R., Rittle, K.E., Ngo, P.L., Yang, Z., Selnick, H.G., Graham, S.L., Munshi, S., McGaughey, G.B., Holloway, M.K., Simon, A.J., Price, E.A., Sankaranarayanan, S., Colussi, D., Tugusheva, K., Lai, M.T., Espeseth, A.S., Xu, M., Huang, Q., Wolfe, A., Pietrak, B., Zuck, P., Levorse, D.A., Hazuda, D., Vacca, J.P. J. Med. Chem. (2008)
- Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1. Barrow, J.C., Rittle, K.E., Ngo, P.L., Selnick, H.G., Graham, S.L., Pitzenberger, S.M., McGaughey, G.B., Colussi, D., Lai, M.T., Huang, Q., Tugusheva, K., Espeseth, A.S., Simon, A.J., Munshi, S.K., Vacca, J.P. ChemMedChem (2007)
- Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. Barrow, J.C., Nantermet, P.G., Stauffer, S.R., Ngo, P.L., Steinbeiser, M.A., Mao, S.S., Carroll, S.S., Bailey, C., Colussi, D., Bosserman, M., Burlein, C., Cook, J.J., Sitko, G., Tiller, P.R., Miller-Stein, C.M., Rose, M., McMasters, D.R., Vacca, J.P., Selnick, H.G. J. Med. Chem. (2003)
- Discovery and initial structure-activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists. Barrow, J.C., Nantermet, P.G., Selnick, H.G., Glass, K.L., Ngo, P.L., Young, M.B., Pellicore, J.M., Breslin, M.J., Hutchinson, J.H., Freidinger, R.M., Condra, C., Karczewski, J., Bednar, R.A., Gaul, S.L., Stern, A., Gould, R., Connolly, T.M. Bioorg. Med. Chem. Lett. (2001)
