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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

John F. Bowyer

Division of Neurotoxicology


National Center for Toxicological Research/FDA




Name/email consistency: high



  • Division of Neurotoxicology, HFT-132, National Center for Toxicological Research/FDA, Jefferson, USA. 1998 - 2006


  1. Fluoro-Ruby labeling prior to an amphetamine neurotoxic insult shows a definitive massive loss of dopaminergic terminals and axons in the caudate-putamen. Bowyer, J.F., Schmued, L.C. Brain Res. (2006) [Pubmed]
  2. High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus. Bowyer, J.F., Ali, S. Synapse (2006) [Pubmed]
  3. Glutamate N-methyl-D-aspartate and dopamine receptors have contrasting effects on the limbic versus the somatosensory cortex with respect to amphetamine-induced neurodegeneration. Bowyer, J.F., Delongchamp, R.R., Jakab, R.L. Brain Res. (2004) [Pubmed]
  4. Plasma levels of parent compound and metabolites after doses of either d-fenfluramine or d-3,4-methylenedioxymethamphetamine (MDMA) that produce long-term serotonergic alterations. Bowyer, J.F., Young, J.F., Slikker, W., Itzak, Y., Mayorga, A.J., Newport, G.D., Ali, S.F., Frederick, D.L., Paule, M.G. Neurotoxicology (2003) [Pubmed]
  5. Phenobarbital and dizocilpine can block methamphetamine-induced neurotoxicity in mice by mechanisms that are independent of thermoregulation. Bowyer, J.F., Holson, R.R., Miller, D.B., O'Callaghan, J.P. Brain Res. (2001) [Pubmed]
  6. L-ephedrine-induced neurodegeneration in the parietal cortex and thalamus of the rat is dependent on hyperthermia and can be altered by the process of in vivo brain microdialysis. Bowyer, J.F., Hopkins, K.J., Jakab, R., Ferguson, S.A. Toxicol. Lett. (2001) [Pubmed]
  7. An evaluation of l-ephedrine neurotoxicity with respect to hyperthermia and caudate/putamen microdialysate levels of ephedrine, dopamine, serotonin, and glutamate. Bowyer, J.F., Newport, G.D., Slikker, W., Gough, B., Ferguson, S.A., Tor-Agbidye, J. Toxicol. Sci. (2000) [Pubmed]
  8. Changes in mRNA levels for heat-shock/stress proteins (Hsp) and a secretory vesicle associated cysteine-string protein (Csp1) after amphetamine (AMPH) exposure. Bowyer, J.F., Davies, D.L. Ann. N. Y. Acad. Sci. (1999) [Pubmed]
  9. Neuronal degeneration in rat forebrain resulting from D-amphetamine-induced convulsions is dependent on seizure severity and age. Bowyer, J.F., Peterson, S.L., Rountree, R.L., Tor-Agbidye, J., Wang, G.J. Brain Res. (1998) [Pubmed]
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