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James Spencer

Department of Cellular and Molecular Medicine

University of Bristol School of Medical Sciences

University Walk

Bristol BS8 1TD

[email]@bristol.ac.uk

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Affiliation

Department of Cellular and Molecular Medicine, University of Bristol School of Medical Sciences, University Walk, Bristol BS8 1TD, UK. 2001 - 2010

References

Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. Spencer, J., Murphy, L.M., Conners, R., Sessions, R.B., Gamblin, S.J. J. Mol. Biol. (2010) [Pubmed]
A new approach to the inhibition of metallo-beta-lactamases. Spencer, J., Walsh, T.R. Angew. Chem. Int. Ed. Engl. (2006) [Pubmed]
Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase. Spencer, J., Clarke, A.R., Walsh, T.R. J. Biol. Chem. (2001) [Pubmed]