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John Ashby

Syngenta Central Toxicology Laboratory

Alderley Park

Cheshire SK10 4TJ

Macclesfield

UK

[email]@syngenta.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Syngenta Central Toxicology Laboratory, Alderley Park, Cheshire SK10 4TJ, Macclesfield, UK. 2001 - 2004
  • Zeneca CTL, Alderley Park, Nr Macclesfield, Cheshire, UK. 2000

References

  1. Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay. Ashby, J., Lefevre, P.A., Tinwell, H., Odum, J., Owens, W. Regul. Toxicol. Pharmacol. (2004) [Pubmed]
  2. Natural variability and the influence of concurrent control values on the detection and interpretation of low-dose or weak endocrine toxicities. Ashby, J., Tinwell, H., Odum, J., Lefevre, P. Environ. Health Perspect. (2004) [Pubmed]
  3. The leading role and responsibility of the international scientific community in test development. Ashby, J. Toxicol. Lett. (2003) [Pubmed]
  4. The intact immature rodent uterotrophic bioassay: possible effects on assay sensitivity of vomeronasal signals from male rodents and strain differences. Ashby, J., Owens, W., Odum, J., Tinwell, H. Environ. Health Perspect. (2003) [Pubmed]
  5. Concept evaluation: androgen-stimulated immature intact male rats as an assay for antiandrogens. Ashby, J., Owens, W., Lefevre, P.A. Regul. Toxicol. Pharmacol. (2002) [Pubmed]
  6. Scientific issues associated with the validation of in vitro and in vivo methods for assessing endocrine disrupting chemicals. Ashby, J. Toxicology (2002) [Pubmed]
  7. Testing for endocrine disruption post-EDSTAC: extrapolation of low dose rodent effects to humans. Ashby, J. Toxicol. Lett. (2001) [Pubmed]
  8. Continuing ability of the rodent bone marrow micronucleus assay to act as a predictor of the possible germ cell mutagenicity of chemicals. Ashby, J., Tinwell, H. Mutat. Res. (2001) [Pubmed]
  9. DNA adducts, estrogenicity and rodent diets. Ashby, J., Tinwell, H., Odum, J. Mutat. Res. (2001) [Pubmed]
  10. Mouse uterine carcinogenicity of genistein: the currently most secure example of non-genotoxic rodent carcinogenicity?. Ashby, J. Mutat. Res. (2001) [Pubmed]
  11. Expectations for transgenic rodent cancer bioassay models. Ashby, J. Toxicol. Pathol (2001) [Pubmed]
  12. Increasing the sensitivity of the rodent uterotrophic assay to estrogens, with particular reference to bisphenol A. Ashby, J. Environ. Health Perspect. (2001) [Pubmed]
  13. Replacement of surgical castration by GnRH inhibition for rat prostate androgen receptor preparations. Ashby, J., Lefevre, P.A. J. Appl. Toxicol (2001) [Pubmed]
  14. Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S. Ashby, J., Tinwell, H., Plautz, J., Twomey, K., Lefevre, P.A. Regul. Toxicol. Pharmacol. (2001) [Pubmed]
  15. Getting the problem of endocrine disruption into focus: the need for a pause for thought. Ashby, J. APMIS (2000) [Pubmed]
 
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