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John T. Hunt

Oncology Drug Discovery

Bristol-Myers Squibb Research and Development

Princeton

NJ 08543-4000

USA

[email]@bms.com

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Affiliations

Oncology Drug Discovery, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000, USA. 2009
Departments of Oncology Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, P. O. Box 4000, Princeton, USA. 2004
Department of Oncology Chemistry, Chemistry Core Resources, Metabolism and Pharmacokinetics, and Oncology Drug Discovery, USA. 2000

References

Discovery of ixabepilone. Hunt, J.T. Mol. Cancer Ther. (2009) [Pubmed]
Discovery of the pyrrolo[2,1-f][1,2,4]triazine nucleus as a new kinase inhibitor template. Hunt, J.T., Mitt, T., Borzilleri, R., Gullo-Brown, J., Fargnoli, J., Fink, B., Han, W.C., Mortillo, S., Vite, G., Wautlet, B., Wong, T., Yu, C., Zheng, X., Bhide, R. J. Med. Chem. (2004) [Pubmed]
Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity. Hunt, J.T., Ding, C.Z., Batorsky, R., Bednarz, M., Bhide, R., Cho, Y., Chong, S., Chao, S., Gullo-Brown, J., Guo, P., Kim, S.H., Lee, F.Y., Leftheris, K., Miller, A., Mitt, T., Patel, M., Penhallow, B.A., Ricca, C., Rose, W.C., Schmidt, R., Slusarchyk, W.A., Vite, G., Manne, V. J. Med. Chem. (2000) [Pubmed]