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Tomoyuki Kawase

Division of Oral Bioengineering

Department of Tissue Regeneration and Reconstitution

Institute of Medicine and Dentistry

Niigata University



Name/email consistency: high



  • Division of Oral Bioengineering, Department of Tissue Regeneration and Reconstitution, Institute of Medicine and Dentistry, Niigata University, Japan. 2006 - 2010
  • Department of Signal Transduction Research, Division of Cellular Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, Japan. 2003 - 2005
  • Division of Cellular Pharmacology, Department of Signal Transduction Research, Course for Molecular and Cellular Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan. 2003
  • Department of Pharmacology, Niigata University School of Dentistry, Japan. 1998 - 1999


  1. Human periosteum-derived cells combined with superporous hydroxyapatite blocks used as an osteogenic bone substitute for periodontal regenerative therapy: an animal implantation study using nude mice. Kawase, T., Okuda, K., Kogami, H., Nakayama, H., Nagata, M., Sato, T., Wolff, L.F., Yoshie, H. J. Periodontol. (2010) [Pubmed]
  2. Osteogenic activity of human periosteal sheets cultured on salmon collagen-coated ePTFE meshes. Kawase, T., Okuda, K., Kogami, H., Nakayama, H., Nagata, M., Yoshie, H. J. Mater. Sci. Mater. Med (2010) [Pubmed]
  3. Characterization of human cultured periosteal sheets expressing bone-forming potential: in vitro and in vivo animal studies. Kawase, T., Okuda, K., Kogami, H., Nakayama, H., Nagata, M., Nakata, K., Yoshie, H. J. Tissue. Eng. Regen. Med (2009) [Pubmed]
  4. Extracellular ATP and ATPgammaS suppress the proliferation of human periodontal ligament cells by different mechanisms. Kawase, T., Okuda, K., Yoshie, H. J. Periodontol. (2007) [Pubmed]
  5. A Hepatocyte Growth Factor (HGF)/receptor autocrine loop regulates constitutive self-renewal of human periodontal ligament cells but reduces sensitivity to exogenous HGF. Kawase, T., Okuda, K., Yoshie, H. J. Periodontol. (2006) [Pubmed]
  6. In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or platelet-derived growth factor. Kawase, T., Okuda, K., Saito, Y., Yoshie, H. J. Periodontol. (2005) [Pubmed]
  7. Immature osteoblastic MG63 cells possess two calcitonin gene-related peptide receptor subtypes that respond differently to [Cys(Acm)(2,7)] calcitonin gene-related peptide and CGRP(8-37). Kawase, T., Okuda, K., Burns, D.M. Am. J. Physiol., Cell Physiol. (2005) [Pubmed]
  8. Platelet-rich plasma provides nucleus for mineralization in cultures of partially differentiated periodontal ligament cells. Kawase, T., Okuda, K., Saito, Y., Amizuka, N., Suzuki, H., Yoshie, H. In Vitro Cell. Dev. Biol. Anim. (2005) [Pubmed]
  9. Granulocyte colony-stimulating factor synergistically augments 1,25-dihydroxyvitamin D3-induced monocytic differentiation in murine bone marrow cell cultures. Kawase, T., Oguro, A. Horm. Metab. Res. (2004) [Pubmed]
  10. Immature human osteoblastic MG63 cells predominantly express a subtype 1-like CGRP receptor that inactivates extracellular signal response kinase by a cAMP-dependent mechanism. Kawase, T., Okuda, K., Burns, D.M. Eur. J. Pharmacol. (2003) [Pubmed]
  11. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. Kawase, T., Okuda, K., Wolff, L.F., Yoshie, H. J. Periodontol. (2003) [Pubmed]
  12. Possible regulation of epidermal growth factor-receptor tyrosine autophosphorylation by calcium and G proteins in chemically permeabilized rat UMR106 cells. Kawase, T., Orikasa, M., Oguro, A., Burns, D.M. Arch. Oral Biol. (1999) [Pubmed]
  13. Calcitonin gene-related peptide stimulates potassium efflux through adenosine triphosphate-sensitive potassium channels and produces membrane hyperpolarization in osteoblastic UMR106 cells. Kawase, T., Burns, D.M. Endocrinology (1998) [Pubmed]
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