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Kazuaki Niikura

Pharmacology Research Laboratories

Astellas Pharma Inc.

Japan

[email]@jp.astellas.com

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Affiliations

Pharmacology Research Laboratories, Astellas Pharma Inc., Japan. 2005 - 2007
Data Management & Regulatory Support Department, Astellas Research Service Co., Ltd., Ibaraki, Japan. 2006 - 2007

References

FR177995, a novel vacuolar ATPase inhibitor, exerts not only an inhibitory effect on bone destruction but also anti-immunoinflammatory effects in adjuvant-induced arthritic rats. Niikura, K., Nakajima, S., Takano, M., Yamazaki, H. Bone (2007) [Pubmed]
Effect of a V-ATPase inhibitor, FR202126, in syngeneic mouse model of experimental bone metastasis. Niikura, K. Cancer Chemother. Pharmacol. (2007) [Pubmed]
Vacuolar ATPase as a drug discovery target. Niikura, K. Drug News Perspect. (2006) [Pubmed]
Comparative analysis of the effects of a novel vacuolar adenosine 5'-triphosphatase inhibitor, FR202126, and doxycycline on bone loss caused by experimental periodontitis in rats. Niikura, K. J. Periodontol. (2006) [Pubmed]
A vacuolar ATPase inhibitor, FR167356, prevents bone resorption in ovariectomized rats with high potency and specificity: potential for clinical application. Niikura, K., Takeshita, N., Takano, M. J. Bone Miner. Res. (2005) [Pubmed]
A novel inhibitor of vacuolar ATPase, FR202126, prevents alveolar bone destruction in experimental periodontitis in rats. Niikura, K., Takeshita, N., Chida, N. J. Toxicol. Sci (2005) [Pubmed]