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Kar Neng Lai

Nephrology Center

10th floor

Li Shu Pui Block

Hong Kong Sanatorium and Hospital

Hong Kong


Name/email consistency: high



  • Nephrology Center, 10th floor, Li Shu Pui Block, Hong Kong Sanatorium and Hospital, Hong Kong. 2012
  • Division of Nephrology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong. 1998 - 2011


  1. Pathogenesis of IgA nephropathy. Lai, K.N. Nat. Rev. Nephrol (2012) [Pubmed]
  2. Additive effect of PPAR-γ agonist and ARB in treatment of experimental IgA nephropathy. Lai, K.N., Chan, L.Y., Guo, H., Tang, S.C., Leung, J.C. Pediatr. Nephrol. (2011) [Pubmed]
  3. Inflammation in peritoneal dialysis. Lai, K.N., Leung, J.C. Nephron. Clin. Pract (2010) [Pubmed]
  4. Podocyte injury induced by mesangial-derived cytokines in IgA nephropathy. Lai, K.N., Leung, J.C., Chan, L.Y., Saleem, M.A., Mathieson, P.W., Tam, K.Y., Xiao, J., Lai, F.M., Tang, S.C. Nephrol. Dial. Transplant. (2009) [Pubmed]
  5. Recurrent oral ulcers and diarrhea in a renal transplant patient. Behcet's disease (associated with IgA nephropathy) and acute tacrolimus nephrotoxicity. Lai, K.N., Lai, A.S., Yap, D.Y., Ng, M.M. Kidney Int. (2009) [Pubmed]
  6. Activation of podocytes by mesangial-derived TNF-alpha: glomerulo-podocytic communication in IgA nephropathy. Lai, K.N., Leung, J.C., Chan, L.Y., Saleem, M.A., Mathieson, P.W., Lai, F.M., Tang, S.C. Am. J. Physiol. Renal Physiol. (2008) [Pubmed]
  7. Mediators of inflammation and fibrosis. Lai, K.N., Tang, S.C., Leung, J.C. Perit. Dial. Int (2007) [Pubmed]
  8. Membranous nephropathy: when and how to treat. Lai, K.N. Kidney Int. (2007) [Pubmed]
  9. Ganoderma extract prevents albumin-induced oxidative damage and chemokines synthesis in cultured human proximal tubular epithelial cells. Lai, K.N., Chan, L.Y., Tang, S.C., Leung, J.C. Nephrol. Dial. Transplant. (2006) [Pubmed]
  10. Pathogenic IgA in IgA nephropathy: still the blind men and the elephant?. Lai, K.N. Kidney Int. (2006) [Pubmed]
  11. Mechanisms of tubulointerstitial injury in IgA nephropathy. Lai, K.N., Chan, L.Y., Leung, J.C. Kidney Int. Suppl. (2005) [Pubmed]
  12. Treatment for lupus nephritis: a revisit. Lai, K.N., Tang, S.C., Mok, C.C. Nephrology. (Carlton) (2005) [Pubmed]
  13. Clinical, Laboratory, and Radiologic Manifestation of SARS. Lai, K.N., Tsang, K.W., Seto, W.H., Ooi, C.G. Curr. Infect. Dis. Rep (2004) [Pubmed]
  14. Mesangial expression of angiotensin II receptor in IgA nephropathy and its regulation by polymeric IgA1. Lai, K.N., Chan, L.Y., Tang, S.C., Tsang, A.W., Li, F.F., Lam, M.F., Lui, S.L., Leung, J.C. Kidney Int. (2004) [Pubmed]
  15. Differential expression of receptors for advanced glycation end-products in peritoneal mesothelial cells exposed to glucose degradation products. Lai, K.N., Leung, J.C., Chan, L.Y., Li, F.F., Tang, S.C., Lam, M.F., Tse, K.C., Yip, T.P., Chan, T.M., Wieslander, A., Vlassara, H. Clin. Exp. Immunol. (2004) [Pubmed]
  16. Role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Lai, K.N., Leung, J.C., Metz, C.N., Lai, F.M., Bucala, R., Lan, H.Y. J. Pathol. (2003) [Pubmed]
  17. Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system. Lai, K.N., Tang, S.C., Guh, J.Y., Chuang, T.D., Lam, M.F., Chan, L.Y., Tsang, A.W., Leung, J.C. J. Am. Soc. Nephrol. (2003) [Pubmed]
  18. Peritoneal function: the role of aquaporins. Lai, K.N., Lam, M.F., Leung, J.C. Perit. Dial. Int (2003) [Pubmed]
  19. Characteristics of polymeric lambda-IgA binding to leukocytes in IgA nephropathy. Lai, K.N., Chan, L.Y., Tang, S.C., Tsang, A.W., Guo, H., Tse, K.C., Yip, T., Leung, J.C. J. Am. Soc. Nephrol. (2002) [Pubmed]
  20. Future directions in the treatment of IgA nephropathy. Lai, K.N. Nephron (2002) [Pubmed]
  21. Expression of aquaporin-3 in human peritoneal mesothelial cells and its up-regulation by glucose in vitro. Lai, K.N., Leung, J.C., Chan, L.Y., Tang, S., Li, F.K., Lui, S.L., Chan, T.M. Kidney Int. (2002) [Pubmed]
  22. Expression of aquaporin-1 in human peritoneal mesothelial cells and its upregulation by glucose in vitro. Lai, K.N., Li, F.K., Lan, H.Y., Tang, S., Tsang, A.W., Chan, D.T., Leung, J.C. J. Am. Soc. Nephrol. (2001) [Pubmed]
  23. Increased survival of mesothelial cells from the peritoneum in peritoneal dialysis fluid. Lai, K.N., Ho, S.K., Leung, J., Tang, S.C., Chan, T.M., Li, F.K. Cell Biol. Int. (2001) [Pubmed]
  24. Effect of low molecular weight heparin on bone metabolism and hyperlipidemia in patients on maintenance hemodialysis. Lai, K.N., Ho, K., Cheung, R.C., Lit, L.C., Lee, S.K., Fung, K.S., Tong, M.K., Lam, C.W. Int. J. Artif. Organs (2001) [Pubmed]
  25. Absence of CD89, polymeric immunoglobulin receptor, and asialoglycoprotein receptor on human mesangial cells. Leung, J.C., Tsang, A.W., Chan, D.T., Lai, K.N. J. Am. Soc. Nephrol. (2000) [Pubmed]
  26. Changes of cytokine profiles during peritonitis in patients on continuous ambulatory peritoneal dialysis. Lai, K.N., Lai, K.B., Lam, C.W., Chan, T.M., Li, F.K., Leung, J.C. Am. J. Kidney Dis. (2000) [Pubmed]
  27. Increased production of hyaluronan by peritoneal cells and its significance in patients on CAPD. Lai, K.N., Szeto, C.C., Lai, K.B., Lam, C.W., Chan, D.T., Leung, J.C. Am. J. Kidney Dis. (1999) [Pubmed]
  28. Growth factors in continuous ambulatory peritoneal dialysis effluent. Their relation with peritoneal transport of small solutes. Lai, K.N., Lai, K.B., Szeto, C.C., Lam, C.W., Leung, J.C. Am. J. Nephrol. (1999) [Pubmed]
  29. Gene expression and synthesis of natriuretic peptides by cultured human glomerular cells. Lai, K.N., Leung, J.C., Yandle, T.G., Fisher, S., Nicholls, M.G. J. Hypertens. (1999) [Pubmed]
  30. Gene expression of the renin-angiotensin system in human kidney. Lai, K.N., Leung, J.C., Lai, K.B., To, W.Y., Yeung, V.T., Lai, F.M. J. Hypertens. (1998) [Pubmed]
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