Ke-He Ruan
The Vascular Biology Research Center and Division of Hematology
Department of Internal Medicine
The University of Texas Health Science Center
Houston
USA
Name/email consistency: high
- Implications of the molecular basis of prostacyclin biosynthesis and signaling in pharmaceutical designs. Ruan, K.H., Dogné, J.M. Curr. Pharm. Des. (2006)
- The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase. Ruan, K.H., Deng, H., Wu, J., So, S.P. Arch. Biochem. Biophys. (2005)
- Solution structure of a common substrate mimetic of cyclooxygenase-downstream synthases bound to an engineered thromboxane A2 synthase using a high-resolution NMR technique. Ruan, K.H., Wu, J., Wang, L.H. Arch. Biochem. Biophys. (2005)
- NMR structure of the thromboxane A2 receptor ligand recognition pocket. Ruan, K.H., Wu, J., So, S.P., Jenkins, L.A., Ruan, C.H. Eur. J. Biochem. (2004)
- Advance in understanding the biosynthesis of prostacyclin and thromboxane A2 in the endoplasmic reticulum membrane via the cyclooxygenase pathway. Ruan, K.H. Mini. Rev. Med. Chem (2004)
- Evidence of the residues involved in ligand recognition in the second extracellular loop of the prostacyclin receptor characterized by high resolution 2D NMR techniques. Ruan, K.H., Wu, J., So, S.P., Jenkins, L.A. Arch. Biochem. Biophys. (2003)
- Solution structure and topology of the N-terminal membrane anchor domain of a microsomal cytochrome P450: prostaglandin I2 synthase. Ruan, K.H., So, S.P., Zheng, W., Wu, J., Li, D., Kung, J. Biochem. J. (2002)
