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Masataka Kuwana

Division of Rheumatology

Department of Internal Medicine

Keio University School of Medicine

35 Shinanomachi



Name/email consistency: high



  • Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Japan. 2001 - 2009
  • Keio University School of Medicine, Tokyo, Japan. 2002 - 2006


  1. Long-term beneficial effects of statins on vascular manifestations in patients with systemic sclerosis. Kuwana, M., Okazaki, Y., Kaburaki, J. Mod. Rheumatol (2009) [Pubmed]
  2. Splenic macrophages maintain the anti-platelet autoimmune response via uptake of opsonized platelets in patients with immune thrombocytopenic purpura. Kuwana, M., Okazaki, Y., Ikeda, Y. J. Thromb. Haemost. (2009) [Pubmed]
  3. The role of autoantibody-producing plasma cells in immune thrombocytopenic purpura refractory to rituximab. Kuwana, M., Iki, S., Urabe, A. Am. J. Hematol. (2007) [Pubmed]
  4. Preliminary laboratory based diagnostic criteria for immune thrombocytopenic purpura: evaluation by multi-center prospective study. Kuwana, M., Kurata, Y., Fujimura, K., Fujisawa, K., Wada, H., Nagasawa, T., Nomura, S., Kojima, T., Yagi, H., Ikeda, Y. J. Thromb. Haemost. (2006) [Pubmed]
  5. Two types of autoantibody-mediated thrombocytopenia in patients with systemic lupus erythematosus. Kuwana, M., Kaburaki, J., Okazaki, Y., Miyazaki, H., Ikeda, Y. Rheumatology. (Oxford) (2006) [Pubmed]
  6. Increase in circulating endothelial precursors by atorvastatin in patients with systemic sclerosis. Kuwana, M., Kaburaki, J., Okazaki, Y., Yasuoka, H., Kawakami, Y., Ikeda, Y. Arthritis Rheum. (2006) [Pubmed]
  7. Endothelial differentiation potential of human monocyte-derived multipotential cells. Kuwana, M., Okazaki, Y., Kodama, H., Satoh, T., Kawakami, Y., Ikeda, Y. Stem. Cells (2006) [Pubmed]
  8. Potential benefit of statins for vascular disease in systemic sclerosis. Kuwana, M. Curr. Opin. Rheumatol (2006) [Pubmed]
  9. Binding of beta 2-glycoprotein I to anionic phospholipids facilitates processing and presentation of a cryptic epitope that activates pathogenic autoreactive T cells. Kuwana, M., Matsuura, E., Kobayashi, K., Okazaki, Y., Kaburaki, J., Ikeda, Y., Kawakami, Y. Blood (2005) [Pubmed]
  10. The role of autoreactive T-cells in the pathogenesis of idiopathic thrombocytopenic purpura. Kuwana, M., Ikeda, Y. Int. J. Hematol. (2005) [Pubmed]
  11. Enzyme-linked immunosorbent assay for detection of anti-RNA polymerase III antibody: analytical accuracy and clinical associations in systemic sclerosis. Kuwana, M., Okano, Y., Pandey, J.P., Silver, R.M., Fertig, N., Medsger, T.A. Arthritis Rheum. (2005) [Pubmed]
  12. Initial laboratory findings useful for predicting the diagnosis of idiopathic thrombocytopenic purpura. Kuwana, M., Okazaki, Y., Satoh, T., Asahi, A., Kajihara, M., Ikeda, Y. Am. J. Med. (2005) [Pubmed]
  13. Effect of a single injection of humanized anti-CD154 monoclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura. Kuwana, M., Nomura, S., Fujimura, K., Nagasawa, T., Muto, Y., Kurata, Y., Tanaka, S., Ikeda, Y. Blood (2004) [Pubmed]
  14. Defective vasculogenesis in systemic sclerosis. Kuwana, M., Okazaki, Y., Yasuoka, H., Kawakami, Y., Ikeda, Y. Lancet (2004) [Pubmed]
  15. Beta2-glycoprotein I: antiphospholipid syndrome and T-cell reactivity. Kuwana, M. Thromb. Res. (2004) [Pubmed]
  16. Suppression of autoreactive T-cell response to glycoprotein IIb/IIIa by blockade of CD40/CD154 interaction: implications for treatment of immune thrombocytopenic purpura. Kuwana, M., Kawakami, Y., Ikeda, Y. Blood (2003) [Pubmed]
  17. Detection of circulating B cells secreting platelet-specific autoantibody is useful in the diagnosis of autoimmune thrombocytopenia. Kuwana, M., Okazaki, Y., Kaburaki, J., Ikeda, Y. Am. J. Med. (2003) [Pubmed]
  18. Evaluation of functional disability using the health assessment questionnaire in Japanese patients with systemic sclerosis. Kuwana, M., Sato, S., Kikuchi, K., Kawaguchi, Y., Fujisaku, A., Misaki, Y., Hatamochi, A., Kondo, H., Takehara, K. J. Rheumatol. (2003) [Pubmed]
  19. Autoreactive CD4(+) T cells to beta(2)-glycoprotein I in patients with antiphospholipid syndrome. Kuwana, M. Autoimmun. Rev (2003) [Pubmed]
  20. Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. Kuwana, M., Okazaki, Y., Kodama, H., Izumi, K., Yasuoka, H., Ogawa, Y., Kawakami, Y., Ikeda, Y. J. Leukoc. Biol. (2003) [Pubmed]
  21. HLA class II alleles in systemic sclerosis patients with anti-RNA polymerase I/III antibody: associations with subunit reactivities. Kuwana, M., Pandey, J.P., Silver, R.M., Kawakami, Y., Kaburaki, J. J. Rheumatol. (2003) [Pubmed]
  22. Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura. Kuwana, M., Okazaki, Y., Kaburaki, J., Kawakami, Y., Ikeda, Y. J. Immunol. (2002) [Pubmed]
  23. Differences in autoantibody response to Th/To between systemic sclerosis and other autoimmune diseases. Kuwana, M., Kimura, K., Hirakata, M., Kawakami, Y., Ikeda, Y. Ann. Rheum. Dis. (2002) [Pubmed]
  24. Autoantibody to c-Mpl (thrombopoietin receptor) in systemic lupus erythematosus: relationship to thrombocytopenia with megakaryocytic hypoplasia. Kuwana, M., Okazaki, Y., Kajihara, M., Kaburaki, J., Miyazaki, H., Kawakami, Y., Ikeda, Y. Arthritis Rheum. (2002) [Pubmed]
  25. Identification of an immunodominant epitope on RNA polymerase III recognized by systemic sclerosis sera: application to enzyme-linked immunosorbent assay. Kuwana, M., Kimura, K., Kawakami, Y. Arthritis Rheum. (2002) [Pubmed]
  26. Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets. Kuwana, M. Hum. Immunol. (2002) [Pubmed]
  27. Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T cells in patients with immune thrombocytopenic purpura. Kuwana, M., Kaburaki, J., Kitasato, H., Kato, M., Kawai, S., Kawakami, Y., Ikeda, Y. Blood (2001) [Pubmed]
  28. Induction of antigen-specific human CD4(+) T cell anergy by peripheral blood DC2 precursors. Kuwana, M., Kaburaki, J., Wright, T.M., Kawakami, Y., Ikeda, Y. Eur. J. Immunol. (2001) [Pubmed]
  29. Autoantibodies to the amino-terminal fragment of beta-fodrin expressed in glandular epithelial cells in patients with Sjögren's syndrome. Kuwana, M., Okano, T., Ogawa, Y., Kaburaki, J., Kawakami, Y. J. Immunol. (2001) [Pubmed]
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