Lawrence H. Lash
Department of Pharmacology
Wayne State University School of Medicine
Detroit
MI 48201
USA
Name/email consistency: high
- Renal membrane transport of glutathione in toxicology and disease. Lash, L.H. Vet. Pathol. (2011)
- Renal glutathione transport: Identification of carriers, physiological functions, and controversies. Lash, L.H. Biofactors (2009)
- Drug metabolism enzyme expression and activity in primary cultures of human proximal tubular cells. Lash, L.H., Putt, D.A., Cai, H. Toxicology (2008)
- Mitochondrial GSH transport and intestinal cell injury: a commentary on "Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis". Lash, L.H. Free Radic. Biol. Med. (2008)
- Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione. Lash, L.H., Putt, D.A., Huang, P., Hueni, S.E., Parker, J.C. Toxicology (2007)
- Role of rat organic anion transporter 3 (Oat3) in the renal basolateral transport of glutathione. Lash, L.H., Putt, D.A., Xu, F., Matherly, L.H. Chem. Biol. Interact. (2007)
- Interactive toxicity of inorganic mercury and trichloroethylene in rat and human proximal tubules: effects on apoptosis, necrosis, and glutathione status. Lash, L.H., Putt, D.A., Hueni, S.E., Payton, S.G., Zwickl, J. Toxicol. Appl. Pharmacol. (2007)
- Influence of compensatory renal growth on susceptibility of primary cultures of renal cells to chemically induced injury. Lash, L.H., Putt, D.A., Zalups, R.K. Toxicol. Sci. (2006)
- Mitochondrial glutathione transport: physiological, pathological and toxicological implications. Lash, L.H. Chem. Biol. Interact. (2006)
- Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine. Lash, L.H., Putt, D.A., Parker, J.C. J. Toxicol. Environ. Health Part A (2006)
- Membrane transport function in primary cultures of human proximal tubular cells. Lash, L.H., Putt, D.A., Cai, H. Toxicology (2006)
- Role of glutathione transport processes in kidney function. Lash, L.H. Toxicol. Appl. Pharmacol. (2005)
- Molecular markers of trichloroethylene-induced toxicity in human kidney cells. Lash, L.H., Putt, D.A., Hueni, S.E., Horwitz, B.P. Toxicol. Appl. Pharmacol. (2005)
- Role of organic anion and amino acid carriers in transport of inorganic mercury in rat renal basolateral membrane vesicles: influence of compensatory renal growth. Lash, L.H., Hueni, S.E., Putt, D.A., Zalups, R.K. Toxicol. Sci. (2005)
- Genetics and susceptibility to toxic chemicals: do you (or should you) know your genetic profile?. Lash, L.H., Hines, R.N., Gonzalez, F.J., Zacharewski, T.R., Rothstein, M.A. J. Pharmacol. Exp. Ther. (2003)
- Roles of necrosis, Apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells. Lash, L.H., Putt, D.A., Hueni, S.E., Krause, R.J., Elfarra, A.A. J. Pharmacol. Exp. Ther. (2003)
- The mitochondrial benzodiazepine receptor as a potential target protein for drug development: demonstration of functional significance with cell lines exhibiting differential expression of Bcl-2. Lash, L.H. Toxicol. Sci. (2003)
- Renal toxicity of perchloroethylene and S-(1,2,2-trichlorovinyl)glutathione in rats and mice: sex- and species-dependent differences. Lash, L.H., Qian, W., Putt, D.A., Hueni, S.E., Elfarra, A.A., Sicuri, A.R., Parker, J.C. Toxicol. Appl. Pharmacol. (2002)
- Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter. Lash, L.H., Putt, D.A., Matherly, L.H. J. Pharmacol. Exp. Ther. (2002)
- Cellular energetics and glutathione status in NRK-52E cells: toxicological implications. Lash, L.H., Putt, D.A., Hueni, S.E., Cao, W., Xu, F., Kulidjian, S.J., Horwitz, J.P. Biochem. Pharmacol. (2002)
- Biochemical and functional characteristics of cultured renal epithelial cells from uninephrectomized rats: factors influencing nephrotoxicity. Lash, L.H., Putt, D.A., Zalups, R.K. J. Pharmacol. Exp. Ther. (2001)
- Renal and hepatic toxicity of trichloroethylene and its glutathione-derived metabolites in rats and mice: sex-, species-, and tissue-dependent differences. Lash, L.H., Qian, W., Putt, D.A., Hueni, S.E., Elfarra, A.A., Krause, R.J., Parker, J.C. J. Pharmacol. Exp. Ther. (2001)
- Hepatic and renal toxicities associated with perchloroethylene. Lash, L.H., Parker, J.C. Pharmacol. Rev. (2001)
- Metabolism of trichloroethylene. Lash, L.H., Fisher, J.W., Lipscomb, J.C., Parker, J.C. Environ. Health Perspect. (2000)
- Modes of action of trichloroethylene for kidney tumorigenesis. Lash, L.H., Parker, J.C., Scott, C.S. Environ. Health Perspect. (2000)
- Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation. Lash, L.H., Lipscomb, J.C., Putt, D.A., Parker, J.C. Drug Metab. Dispos. (1999)
- Renal cellular transport of exogenous glutathione: heterogeneity at physiological and pharmacological concentrations. Lash, L.H., Putt, D.A. Biochem. Pharmacol. (1999)
- Influence of exogenous thiols on inorganic mercury-induced injury in renal proximal and distal tubular cells from normal and uninephrectomized rats. Lash, L.H., Putt, D.A., Zalups, R.K. J. Pharmacol. Exp. Ther. (1999)
- Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene. Lash, L.H., Putt, D.A., Brashear, W.T., Abbas, R., Parker, J.C., Fisher, J.W. J. Toxicol. Environ. Health Part A (1999)
- Cellular and subcellular heterogeneity of glutathione metabolism and transport in rat kidney cells. Lash, L.H., Visarius, T.M., Sall, J.M., Qian, W., Tokarz, J.J. Toxicology (1998)
