Loren Laine
Division of Gastrointestinal and Liver Diseases
Keck School of Medicine
University of Southern California
Los Angeles
USA
Name/email consistency: high
- Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers. Laine, L., Kivitz, A.J., Bello, A.E., Grahn, A.Y., Schiff, M.H., Taha, A.S. Am. J. Gastroenterol. (2012)
- Randomised clinical trial: a novel rabeprazole extended release 50 mg formulation vs. esomeprazole 40 mg in healing of moderate-to-severe erosive oesophagitis - the results of two double-blind studies. Laine, L., Katz, P.O., Johnson, D.A., Ibegbu, I., Goldstein, M.J., Chou, C., Rossiter, G., Lu, Y. Aliment. Pharmacol. Ther. (2011)
- Risk factors for NSAID-associated upper GI clinical events in a long-term prospective study of 34 701 arthritis patients. Laine, L., Curtis, S.P., Cryer, B., Kaur, A., Cannon, C.P. Aliment. Pharmacol. Ther. (2010)
- Proton pump inhibitor and clopidogrel interaction: fact or fiction? Laine, L., Hennekens, C. Am. J. Gastroenterol. (2010)
- Methodology for randomized trials of patients with nonvariceal upper gastrointestinal bleeding: recommendations from an international consensus conference. Laine, L., Spiegel, B., Rostom, A., Moayyedi, P., Kuipers, E.J., Bardou, M., Sung, J., Barkun, A.N. Am. J. Gastroenterol. (2010)
- How common is diclofenac-associated liver injury? Analysis of 17,289 arthritis patients in a long-term prospective clinical trial. Laine, L., Goldkind, L., Curtis, S.P., Connors, L.G., Yanqiong, Z., Cannon, C.P. Am. J. Gastroenterol. (2009)
- Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Laine, L., McQuaid, K.R. Clin. Gastroenterol. Hepatol. (2009)
- Prescription rates of protective co-therapy for NSAID users at high GI risk and results of attempts to improve adherence to guidelines. Laine, L., Connors, L., Griffin, M.R., Curtis, S.P., Kaur, A., Cannon, C.P. Aliment. Pharmacol. Ther. (2009)
- Proton pump inhibitors and bone fractures?. Laine, L. Am. J. Gastroenterol. (2009)
- Gastric mucosal defense and cytoprotection: bench to bedside. Laine, L., Takeuchi, K., Tarnawski, A. Gastroenterology (2008)
- Intragastric pH with oral vs intravenous bolus plus infusion proton-pump inhibitor therapy in patients with bleeding ulcers. Laine, L., Shah, A., Bemanian, S. Gastroenterology (2008)
- Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac. Laine, L., Curtis, S.P., Langman, M., Jensen, D.M., Cryer, B., Kaur, A., Cannon, C.P. Gastroenterology (2008)
- COX-2 selective inhibitors in the treatment of osteoarthritis. Laine, L., White, W.B., Rostom, A., Hochberg, M. Semin. Arthritis Rheum. (2008)
- Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Laine, L., Curtis, S.P., Cryer, B., Kaur, A., Cannon, C.P. Lancet (2007)
- Systematic review: the lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs. Laine, L., Smith, R., Min, K., Chen, C., Dubois, R.W. Aliment. Pharmacol. Ther. (2006)
- GI risk and risk factors of NSAIDs. Laine, L. J. Cardiovasc. Pharmacol. (2006)
- Review article: gastrointestinal bleeding with low-dose aspirin - what's the risk?. Laine, L. Aliment. Pharmacol. Ther. (2006)
- Ulcer formation with low-dose enteric-coated aspirin and the effect of COX-2 selective inhibition: a double-blind trial. Laine, L., Maller, E.S., Yu, C., Quan, H., Simon, T. Gastroenterology (2004)
- Serious lower gastrointestinal clinical events with nonselective NSAID or coxib use. Laine, L., Connors, L.G., Reicin, A., Hawkey, C.J., Burgos-Vargas, R., Schnitzer, T.J., Yu, Q., Bombardier, C. Gastroenterology (2003)
- Gastrointestinal health care resource utilization with chronic use of COX-2-specific inhibitors versus traditional NSAIDs. Laine, L., Wogen, J., Yu, H. Gastroenterology (2003)
- Is it time for quadruple therapy to be first line?. Laine, L. Can. J. Gastroenterol. (2003)
- Review article: the effect of Helicobacter pylori infection on nonsteroidal anti-inflammatory drug-induced upper gastrointestinal tract injury. Laine, L. Aliment. Pharmacol. Ther. (2002)
- Helicobacter pylori eradication does not worsen quality of life related to reflux symptoms: a prospective trial. Laine, L., Dhir, V. Aliment. Pharmacol. Ther. (2002)
- Review article: esomeprazole in the treatment of Helicobacter pylori. Laine, L. Aliment. Pharmacol. Ther. (2002)
- Stratifying the risk of NSAID-related upper gastrointestinal clinical events: results of a double-blind outcomes study in patients with rheumatoid arthritis. Laine, L., Bombardier, C., Hawkey, C.J., Davis, B., Shapiro, D., Brett, C., Reicin, A. Gastroenterology (2002)
- Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient. Laine, L. Gastroenterology (2001)
- Review article: potential gastrointestinal effects of long-term acid suppression with proton pump inhibitors. Laine, L., Ahnen, D., McClain, C., Solcia, E., Walsh, J.H. Aliment. Pharmacol. Ther. (2000)
- A randomized trial comparing the effect of rofecoxib, a cyclooxygenase 2-specific inhibitor, with that of ibuprofen on the gastroduodenal mucosa of patients with osteoarthritis. Rofecoxib Osteoarthritis Endoscopy Study Group. Laine, L., Harper, S., Simon, T., Bath, R., Johanson, J., Schwartz, H., Stern, S., Quan, H., Bolognese, J. Gastroenterology (1999)
- Low rate of emergence of clarithromycin-resistant Helicobacter pylori with amoxycillin co-therapy. Laine, L., Suchower, L., Frantz, J., Connors, A., Neil, G. Aliment. Pharmacol. Ther. (1998)
