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Werner K. Lutz

Department of Toxicology

University of Würzburg

Versbacher St. 9

97078 Würzburg

Germany

[email]@*.uni-wuerzburg.de

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Toxicology, University of Würzburg, Versbacher St. 9, 97078 Würzburg, Germany. 1998 - 2009
  • Seminar for Statistics, Swiss Federal Institute of Technology, CH-8092 Zürich, Switzerland. 2002

References

  1. The Viracept (nelfinavir)--ethyl methanesulfonate case: a threshold risk assessment for human exposure to a genotoxic drug contamination? Lutz, W.K. Toxicol. Lett. (2009) [Pubmed]
  2. Dose-incidence relationships derived from superposition of distributions of individual susceptibility on mechanism-based dose responses for biological effects. Lutz, W.K., Lutz, R.W., Andersen, M.E. Toxicol. Sci. (2006) [Pubmed]
  3. Metabolic profiling of glucuronides in human urine by LC-MS/MS and partial least-squares discriminant analysis for classification and prediction of gender. Lutz, U., Lutz, R.W., Lutz, W.K. Anal. Chem. (2006) [Pubmed]
  4. Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Trösken, E.R., Adamska, M., Arand, M., Zarn, J.A., Patten, C., Völkel, W., Lutz, W.K. Toxicology (2006) [Pubmed]
  5. Different types of combination effects for the induction of micronuclei in mouse lymphoma cells by binary mixtures of the genotoxic agents MMS, MNU, and genistein. Lutz, W.K., Tiedge, O., Lutz, R.W., Stopper, H. Toxicol. Sci. (2005) [Pubmed]
  6. Nonlinearity and thresholds in dose-response relationships for carcinogenicity due to sampling variation, logarithmic dose scaling, or small differences in individual susceptibility. Lutz, W.K., Gaylor, D.W., Conolly, R.B., Lutz, R.W. Toxicol. Appl. Pharmacol. (2005) [Pubmed]
  7. Differences in individual susceptibility to toxic effects of chemicals determine the dose-response relationship and consequences of setting exposure standards. Lutz, W.K. Toxicol. Lett. (2002) [Pubmed]
  8. Statistical calculation of detection limits for DNA adducts using the 32P-postlabeling assay with a standard addition procedure. Lutz, W.K., Lutz, U., Gaylor, D.W. Mutat. Res. (2002) [Pubmed]
  9. Statistical procedures to test for linearity and estimate threshold doses for tumor induction with nonlinear dose-response relationships in bioassays for carcinogenicity. Lutz, R.W., Stahel, W.A., Lutz, W.K. Regul. Toxicol. Pharmacol. (2002) [Pubmed]
  10. Deviation from additivity in mixture toxicity: relevance of nonlinear dose-response relationships and cell line differences in genotoxicity assays with combinations of chemical mutagens and gamma-radiation. Lutz, W.K., Vamvakas, S., Kopp-Schneider, A., Schlatter, J., Stopper, H. Environ. Health Perspect. (2002) [Pubmed]
  11. Susceptibility differences in chemical carcinogenesis linearize the dose-response relationship: threshold doses can be defined only for individuals. Lutz, W.K. Mutat. Res. (2001) [Pubmed]
  12. Threshold dose response for tumor induction by genotoxic carcinogens modeled via cell-cycle delay. Lutz, W.K., Kopp-Schneider, A. Toxicol. Sci. (1999) [Pubmed]
  13. Carcinogens in the diet vs. overnutrition. Individual dietary habits, malnutrition, and genetic susceptibility modify carcinogenic potency and cancer risk. Lutz, W.K. Mutat. Res. (1999) [Pubmed]
  14. Dose-response relationships in chemical carcinogenesis: superposition of different mechanisms of action, resulting in linear-nonlinear curves, practical thresholds, J-shapes. Lutz, W.K. Mutat. Res. (1998) [Pubmed]
 
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