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Maria A. Bednarek

Department of Medicinal Chemistry

Merck Research Laboratories

Rahway

USA

[email]@merck.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, USA. 1999 - 2008
  • Merck Research Laboratories, Department of Medicinal Chemistry, Rahway, NJ 07065, USA. 2007
  • Merck Research Laboratories, Rahway, New Jersey 07065, USA. 1998 - 2002

References

  1. Analogs of alpha-melanocyte stimulating hormone with high agonist potency and selectivity at human melanocortin receptor 1b: the role of Trp(9) in molecular recognition. Bednarek, M.A., Macneil, T., Tang, R., Fong, T.M., Angeles Cabello, M., Maroto, M., Teran, A. Biopolymers (2008) [Pubmed]
  2. Cyclic analogs of alpha-melanocyte-stimulating hormone (alphaMSH) with high agonist potency and selectivity at human melanocortin receptor 1b. Bednarek, M.A., MacNeil, T., Tang, R., Fong, T.M., Cabello, M.A., Maroto, M., Teran, A. Peptides (2008) [Pubmed]
  3. Peptide ligands for the melanin-concentrating hormone (MCH) receptor 1. Bednarek, M.A. Curr. Top. Med. Chem (2007) [Pubmed]
  4. Potent and selective agonists of alpha-melanotropin (alphaMSH) action at human melanocortin receptor 5; linear analogs of alpha-melanotropin. Bednarek, M.A., MacNeil, T., Tang, R., Fong, T.M., Cabello, M.A., Maroto, M., Teran, A. Peptides (2007) [Pubmed]
  5. Potent and selective peptide agonists of alpha-melanocyte stimulating hormone (alphaMSH) action at human melanocortin receptor 5; their synthesis and biological evaluation in vitro. Bednarek, M.A., MacNeil, T., Tang, R., Fong, T.M., Angeles Cabello, M., Maroto, M., Teran, A. Chem. Biol. Drug. Des (2007) [Pubmed]
  6. Potent and selective agonists of human melanocortin receptor 5: cyclic analogues of alpha-melanocyte-stimulating hormone. Bednarek, M.A., MacNeil, T., Tang, R., Fong, T.M., Cabello, M.A., Maroto, M., Teran, A. J. Med. Chem. (2007) [Pubmed]
  7. Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. Bednarek, M.A., Tan, C., Hreniuk, D.L., Palyha, O.C., MacNeil, D.J., Van Der Ploeg, L.H., Howard, A.D., Feighner, S.D. J. Biol. Chem. (2002) [Pubmed]
  8. Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. Bednarek, M.A., Hreniuk, D.L., Tan, C., Palyha, O.C., MacNeil, D.J., Van der Ploeg, L.H., Howard, A.D., Feighner, S.D. Biochemistry (2002) [Pubmed]
  9. Short segment of human melanin-concentrating hormone that is sufficient for full activation of human melanin-concentrating hormone receptors 1 and 2. Bednarek, M.A., Feighner, S.D., Hreniuk, D.L., Palyha, O.C., Morin, N.R., Sadowski, S.J., MacNeil, D.J., Howard, A.D., Van der Ploeg, L.H. Biochemistry (2001) [Pubmed]
  10. Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. Bednarek, M.A., MacNeil, T., Tang, R., Kalyani, R.N., Van der Ploeg, L.H., Weinberg, D.H. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  11. Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. Bednarek, M.A., MacNeil, T., Kalyani, R.N., Tang, R., Van der Ploeg, L.H., Weinberg, D.H. J. Med. Chem. (2001) [Pubmed]
  12. Analogs of lactam derivatives of alpha-melanotropin with basic and acidic residues. Bednarek, M.A., MacNeil, T., Kalyani, R.N., Tang, R., Van der Ploeg, L.H., Weinberg, D.H. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
  13. Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a. Bednarek, M.A., Feighner, S.D., Pong, S.S., McKee, K.K., Hreniuk, D.L., Silva, M.V., Warren, V.A., Howard, A.D., Van Der Ploeg, L.H., Heck, J.V. J. Med. Chem. (2000) [Pubmed]
  14. Analogs of MTII, lactam derivatives of alpha-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5. Bednarek, M.A., Macneil, T., Kalyani, R.N., Tang, R., Van der Ploeg, L.H., Weinberg, D.H. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  15. Amino acids with aryl-keto function in their side chains. Bednarek, M.A. J. Pept. Res. (1998) [Pubmed]
 
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