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Mark A. Babizhayev

Innovative Vision Products

Inc., Moscow Division

Ivanovskaya 20

[email]@mail.ru

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Innovative Vision Products, Inc., Moscow Division, Ivanovskaya 20. 2001 - 2012
  • Innovative Vision Products Inc, County of New Castle, Delaware, Moscow Helmholtz Research Institute for Eye Diseases, Russian Federation. 2011

References

  1. Structural and Functional Properties, Chaperone Activity and Posttranslational Modifications of Alpha-Crystallin and its Related Subunits in the Crystalline Lens: N-acetylcarnosine, Carnosine and Carcinine act as Alpha- Crystallin/Small Heat Shock Protein Enhancers in Prevention and Dissolution of Cataract in Ocular Drug Delivery Formulations of Novel Therapeutic Agents. Babizhayev, M.A. Recent. Pat. Drug. Deliv. Formul (2012) [Pubmed]
  2. Bioactivation antioxidant and transglycating properties of N-acetylcarnosine autoinduction prodrug of a dipeptide L-carnosine in mucoadhesive drug delivery eye-drop formulation: powerful eye health application technique and therapeutic platform. Babizhayev, M.A. Drug. Test. Anal (2011) [Pubmed]
  3. Designation of imidazole-containing dipeptides as pharmacological chaperones. Babizhayev, M.A. Hum. Exp. Toxicol (2011) [Pubmed]
  4. Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for cataract disease. Babizhayev, M.A. Cell Biochem. Funct. (2011) [Pubmed]
  5. A survey and analysis of the role of molecular chaperone proteins and imidazole-containing dipeptide-based compounds as molecular escorts into the skin during stress, injury, water structuring and other types of cutaneous pathophysiology. Babizhayev, M.A., Nikolayev, G.M., Nikolayeva, J.G., Yegorov, Y.E. Int. J. Cosmet. Sci (2011) [Pubmed]
  6. Telomere-dependent senescent phenotype of lens epithelial cells as a biological marker of aging and cataractogenesis: the role of oxidative stress intensity and specific mechanism of phospholipid hydroperoxide toxicity in lens and aqueous. Babizhayev, M.A., Vishnyakova, K.S., Yegorov, Y.E. Fundam. Clin. Pharmacol (2011) [Pubmed]
  7. Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine therapy. Babizhayev, M.A., Yegorov, Y.E. Front. Biosci. (2010) [Pubmed]
  8. Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-L-histidine), carcinine (beta-alanylhistamine) and L-carnosine (beta-alanyl-L-histidine) in targeting peptide compounds as pharmacological chaperones for use in tissue engineering, human disease management and therapy: from in vitro to the clinic. Babizhayev, M.A., Yegorov, Y.E. Recent. Pat. Drug. Deliv. Formul (2010) [Pubmed]
  9. State of the art clinical efficacy and safety evaluation of N-acetylcarnosine dipeptide ophthalmic prodrug. Principles for the delivery, self-bioactivation, molecular targets and interaction with a highly evolved histidyl-hydrazide structure in the treatment and therapeutic management of a group of sight-threatening eye diseases. Babizhayev, M.A., Kasus-Jacobi, A. Curr. Clin. Pharmacol (2009) [Pubmed]
  10. N-Acetylcarnosine sustained drug delivery eye drops to control the signs of ageless vision: glare sensitivity, cataract amelioration and quality of vision currently available treatment for the challenging 50,000-patient population. Babizhayev, M.A., Burke, L., Micans, P., Richer, S.P. Clin. Interv. Aging (2009) [Pubmed]
  11. Potentiation of intraocular absorption and drug metabolism of N-acetylcarnosine lubricant eye drops: drug interaction with sight threatening lipid peroxides in the treatment for age-related eye diseases. Babizhayev, M.A. Drug. Metabol. Drug. Interact (2009) [Pubmed]
  12. N-acetylcarnosine lubricant eyedrops possess all-in-one universal antioxidant protective effects of L-carnosine in aqueous and lipid membrane environments, aldehyde scavenging, and transglycation activities inherent to cataracts: a clinical study of the new vision-saving drug N-acetylcarnosine eyedrop therapy in a database population of over 50,500 patients. Babizhayev, M.A., Micans, P., Guiotto, A., Kasus-Jacobi, A. Am. J. Ther (2009) [Pubmed]
  13. N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications. Babizhayev, M.A., Guiotto, A., Kasus-Jacobi, A. J. Drug. Target (2009) [Pubmed]
  14. Cataract halos: a driving hazard in aging populations. Implication of the Halometer DG test for assessment of intraocular light scatter. Babizhayev, M.A., Minasyan, H., Richer, S.P. Appl. Ergon (2009) [Pubmed]
  15. Analysis of lipid peroxidation and electron microscopic survey of maturation stages during human cataractogenesis: pharmacokinetic assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for cataract prevention. Babizhayev, M.A. Drugs. R. D (2005) [Pubmed]
  16. Rejuvenation of visual functions in older adult drivers and drivers with cataract during a short-term administration of N-acetylcarnosine lubricant eye drops. Babizhayev, M.A. Rejuvenation. Res (2004) [Pubmed]
  17. N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts. Babizhayev, M.A., Deyev, A.I., Yermakova, V.N., Semiletov, Y.A., Davydova, N.G., Kurysheva, N.I., Zhukotskii, A.V., Goldman, I.M. Peptides (2001) [Pubmed]
 
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