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Martine Clozel

Innovation Center

Actelion Pharmaceuticals Ltd

Gewerberstrasse 16




Name/email consistency: high



  • Innovation Center, Actelion Pharmaceuticals Ltd, Gewerberstrasse 16, Allschwil, Switzerland. 2000 - 2006
  • Actelion Pharmaceuticals Ltd., Allschwil, Switzerland. 2002


  1. The urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats. Clozel, M., Hess, P., Qiu, C., Ding, S.S., Rey, M. J. Pharmacol. Exp. Ther. (2006) [Pubmed]
  2. Bosentan, sildenafil, and their combination in the monocrotaline model of pulmonary hypertension in rats. Clozel, M., Hess, P., Rey, M., Iglarz, M., Binkert, C., Qiu, C. Exp. Biol. Med. (Maywood) (2006) [Pubmed]
  3. Role of endothelin in fibrosis and anti-fibrotic potential of bosentan. Clozel, M., Salloukh, H. Ann. Med. (2005) [Pubmed]
  4. Pharmacology of the urotensin-II receptor antagonist palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulfate salt): first demonstration of a pathophysiological role of the urotensin System. Clozel, M., Binkert, C., Birker-Robaczewska, M., Boukhadra, C., Ding, S.S., Fischli, W., Hess, P., Mathys, B., Morrison, K., Müller, C., Müller, C., Nayler, O., Qiu, C., Rey, M., Scherz, M.W., Velker, J., Weller, T., Xi, J.F., Ziltener, P. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  5. Effects of bosentan on cellular processes involved in pulmonary arterial hypertension: do they explain the long-term benefit?. Clozel, M. Ann. Med. (2003) [Pubmed]
  6. Short-term endothelin receptor blockade with tezosentan has both immediate and long-term beneficial effects in rats with myocardial infarction. Clozel, M., Qiu, C., Qiu, C.S., Hess, P., Clozel, J.P. J. Am. Coll. Cardiol. (2002) [Pubmed]
  7. Heart failure--an epidemic of the 21st century? 25th Institut Pasteur Euroconference. 26-27 June 2000, Paris, France. Clozel, M. IDrugs (2000) [Pubmed]
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