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Masayuki Shimada

Laboratory of Reproductive Endocrinology

Graduate School of Biosphere Science

Hiroshima University



Name/email consistency: high



  • Laboratory of Reproductive Endocrinology, Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima. 2002 - 2012


  1. EGF-Like Factors Induce Expansion of the Cumulus Cell-Oocyte Complexes by Activating Calpain-Mediated Cell Movement. Kawashima, I., Liu, Z., Mullany, L.K., Mihara, T., Richards, J.S., Shimada, M. Endocrinology (2012) [Pubmed]
  2. Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization. Shimada, M., Yanai, Y., Okazaki, T., Noma, N., Kawashima, I., Mori, T., Richards, J.S. Development (2008) [Pubmed]
  3. Synaptosomal-associated protein 25 gene expression is hormonally regulated during ovulation and is involved in cytokine/chemokine exocytosis from granulosa cells. Shimada, M., Yanai, Y., Okazaki, T., Yamashita, Y., Sriraman, V., Wilson, M.C., Richards, J.S. Mol. Endocrinol. (2007) [Pubmed]
  4. Down-regulated expression of A disintegrin and metalloproteinase with thrombospondin-like repeats-1 by progesterone receptor antagonist is associated with impaired expansion of porcine cumulus-oocyte complexes. Shimada, M., Nishibori, M., Yamashita, Y., Ito, J., Mori, T., Richards, J.S. Endocrinology (2004) [Pubmed]
  5. Expression of two progesterone receptor isoforms in cumulus cells and their roles during meiotic resumption of porcine oocytes. Shimada, M., Yamashita, Y., Ito, J., Okazaki, T., Kawahata, K., Nishibori, M. J. Mol. Endocrinol. (2004) [Pubmed]
  6. Luteinizing hormone receptor formation in cumulus cells surrounding porcine oocytes and its role during meiotic maturation of porcine oocytes. Shimada, M., Nishibori, M., Isobe, N., Kawano, N., Terada, T. Biol. Reprod. (2003) [Pubmed]
  7. Phosphatidylinositol 3-kinase in cumulus cells is responsible for both suppression of spontaneous maturation and induction of gonadotropin-stimulated maturation of porcine oocytes. Shimada, M., Ito, J., Yamashita, Y., Okazaki, T., Isobe, N. J. Endocrinol. (2003) [Pubmed]
  8. Delay of nuclear maturation and reduction in developmental competence of pig oocytes after mineral oil overlay of in vitro maturation media. Shimada, M., Kawano, N., Terada, T. Reproduction (2002) [Pubmed]
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